Intra-articular TSG-6 delivery from heparin-based microparticles reduces cartilage damage in a rat model of osteoarthritis

Dual Affinity Heparin-Based Hydrogels Achieve Pro-Regenerative Immunomodulation and Microvascular Remodeling

(2017) Molly E. Ogle et al.   ACS Biomaterials-Science & Engineering

Dual Affinity Heparin-Based Hydrogels Achieve Pro-Regenerative Immunomodulation and Microvascular Remodeling

(2017) Molly E. Ogle et al.   ACS Biomaterials Science & Engineering

A novel chondroprotective property of TSG-6 has therapeutic potential for OA

(2016) A.J. Day et al.   OSTEOARTHRITIS AND CARTILAGE

TSG-6 Activity reflects severity of inflammation in knee osteoarthritis and acute joint injury

(2016) C.-H. Chou et al.   OSTEOARTHRITIS AND CARTILAGE

Quantitative pre-clinical screening of therapeutics for joint diseases using contrast enhanced micro-computed tomography

(2016) N.J. Willett et al.   OSTEOARTHRITIS AND CARTILAGE

Heparin-based hydrogels with tunable sulfation & degradation for anti-inflammatory small molecule delivery

(2016) Yifeng Peng et al.   Biomaterials Science

Effect of Selective Heparin Desulfation on Preservation of Bone Morphogenetic Protein-2 Bioactivity after Thermal Stress

(2015) Song P. Seto et al.   BIOCONJUGATE CHEMISTRY

Acute and Temporal Expression of Tumor Necrosis Factor (TNF)-α-stimulated Gene 6 Product, TSG6, in Mesenchymal Stem Cells Creates Microenvironments Required for Their Successful Transplantation into Muscle Tissue

(2015) Shigeko Torihashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heparin desulfation modulates VEGF release and angiogenesis in diabetic wounds

(2015) Uwe Freudenberg et al.   JOURNAL OF CONTROLLED RELEASE

Local Delivery of VEGF and SDF Enhances Endothelial Progenitor Cell Recruitment and Resultant Recovery from Ischemia

(2015) Erin M. Anderson et al.   TISSUE ENGINEERING PART A

Hydrolysis and sulfation pattern effects on release of bioactive bone morphogenetic protein-2 from heparin-based microparticles

(2015) Liane E. Tellier et al.   Journal of Materials Chemistry B

Biohybrid Networks of Selectively Desulfated Glycosaminoglycans for Tunable Growth Factor Delivery

(2014) Andrea Zieris et al.   BIOMACROMOLECULES

Intra-articular injection of micronized dehydrated human amnion/chorion membrane attenuates osteoarthritis development

(2014) Nick J Willett et al.   ARTHRITIS RESEARCH & THERAPY

Localized 3D analysis of cartilage composition and morphology in small animal models of joint degeneration

(2013) T. Thote et al.   OSTEOARTHRITIS AND CARTILAGE

TSG-6 activity as a novel biomarker of progression in knee osteoarthritis

(2013) H.-G. Wisniewski et al.   OSTEOARTHRITIS AND CARTILAGE

A novel, biased-like SDF-1 derivative acts synergistically with starPEG-based heparin hydrogels and improves eEPC migration in vitro

(2012) Lars Baumann et al.   JOURNAL OF CONTROLLED RELEASE

Mesenchymal Stem Cells Attenuate Peritoneal Injury through Secretion of TSG-6

(2012) Nan Wang et al.   PLoS One

Chondrogenesis, chondrocyte differentiation, and articular cartilage metabolism in health and osteoarthritis

(2012) Mary B. Goldring   Therapeutic Advances in Musculoskeletal Disease

Heparin-decorated, hyaluronic acid-based hydrogel particles for the controlled release of bone morphogenetic protein 2

(2011) Xian Xu et al.   Acta Biomaterialia

Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF- B signaling in resident macrophages

(2011) H. Choi et al.   BLOOD

Inflammation in osteoarthritis

(2011) Mary B. Goldring et al.   CURRENT OPINION IN RHEUMATOLOGY

Bioactivity screening of partially desulfated low-molecular-weight heparins: A structure/activity relationship study

(2011) Sucharita Roy et al.   GLYCOBIOLOGY

Controlled release of glial-derived neurotrophic factor from fibrin matrices containing an affinity-based delivery system

(2008) Matthew D. Wood et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Quantitative assessment of articular cartilage morphology via EPIC-μCT

(2008) L. Xie et al.   OSTEOARTHRITIS AND CARTILAGE