Bridging the gap with functional collagen scaffolds: tuning endogenous neural stem cells for severe spinal cord injury repair

Interaction of reactive astrocytes with type I collagen induces astrocytic scar formation through the integrin–N-cadherin pathway after spinal cord injury

(2017) Masamitsu Hara et al.   NATURE MEDICINE

Human placenta-derived mesenchymal stem cells loaded on linear ordered collagen scaffold improves functional recovery after completely transected spinal cord injury in canine

(2017) Sufang Han et al.   Science China-Life Sciences

Transplantation of hUC-MSCs seeded collagen scaffolds reduces scar formation and promotes functional recovery in canines with chronic spinal cord injury

(2017) Xing Li et al.   Scientific Reports

Functionalized collagen scaffold implantation and cAMP administration collectively facilitate spinal cord regeneration

(2016) Xing Li et al.   Acta Biomaterialia

One-year clinical study of NeuroRegen scaffold implantation following scar resection in complete chronic spinal cord injury patients

(2016) Zhifeng Xiao et al.   Science China-Life Sciences

Radially Aligned Electrospun Fibers with Continuous Gradient of SDF1α for the Guidance of Neural Stem Cells

(2016) Xiaoran Li et al.   Small

Functionalized Collagen Scaffold Neutralizing the Myelin-Inhibitory Molecules Promoted Neurites Outgrowth in Vitro and Facilitated Spinal Cord Regeneration in Vivo

(2015) Xing Li et al.   ACS Applied Materials & Interfaces

The linear-ordered collagen scaffold-BDNF complex significantly promotes functional recovery after completely transected spinal cord injury in canine

(2015) Sufang Han et al.   BIOMATERIALS

Endogenous neural stem cell responses to stroke and spinal cord injury

(2015) Catherine-Alexandra Grégoire et al.   GLIA

Myelin-associated inhibitors in axonal growth after CNS injury

(2014) Cédric G Geoffroy et al.   CURRENT OPINION IN NEUROBIOLOGY

Modulation of the proteoglycan receptor PTPσ promotes recovery after spinal cord injury

(2014) Bradley T. Lang et al.   NATURE

Central Canal Ependymal Cells Proliferate Extensively in Response to Traumatic Spinal Cord Injury but Not Demyelinating Lesions

(2014) Steve Lacroix et al.   PLoS One

Promotion of neuronal differentiation of neural progenitor cells by using EGFR antibody functionalized collagen scaffolds for spinal cord injury repair

(2013) Xiaoran Li et al.   BIOMATERIALS

Neural stem cells in the adult spinal cord

(2013) Hanna Sabelström et al.   EXPERIMENTAL NEUROLOGY

The Burden of Acute Traumatic Spinal Cord Injury among Adults in the United States: An Update

(2013) Shalini Selvarajah et al.   JOURNAL OF NEUROTRAUMA

Resident Neural Stem Cells Restrict Tissue Damage and Neuronal Loss After Spinal Cord Injury in Mice

(2013) H. Sabelstrom et al.   SCIENCE

Combination treatment with chondroitinase ABC in spinal cord injury—breaking the barrier

(2013) Rong-Rong Zhao et al.   Neuroscience Bulletin

Emerging therapies for acute traumatic spinal cord injury

(2012) J. R. Wilson et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Motor Axonal Regeneration after Partial and Complete Spinal Cord Transection

(2012) P. Lu et al.   JOURNAL OF NEUROSCIENCE

Reactive Astrogliosis after Spinal Cord Injury—Beneficial and Detrimental Effects

(2012) Soheila Karimi-Abdolrezaee et al.   MOLECULAR NEUROBIOLOGY

NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans

(2012) Travis L Dickendesher et al.   NATURE NEUROSCIENCE

Combination therapies in the CNS: Engineering the environment

(2012) Dylan A. McCreedy et al.   NEUROSCIENCE LETTERS

Animal Models of Neurologic Disorders: A Nonhuman Primate Model of Spinal Cord Injury

(2012) Yvette S. Nout et al.   Neurotherapeutics

Endogenous Proliferation after Spinal Cord Injury in Animal Models

(2012) Ashley McDonough et al.   Stem Cells International

Neuronal Intrinsic Mechanisms of Axon Regeneration

(2011) Kai Liu et al.   Annual Review of Neuroscience

Axon Regeneration Can Facilitate or Suppress Hindlimb Function after Olfactory Ensheathing Glia Transplantation

(2011) A. Takeoka et al.   JOURNAL OF NEUROSCIENCE

Manipulating the glial scar: Chondroitinase ABC as a therapy for spinal cord injury

(2010) Elizabeth J. Bradbury et al.   BRAIN RESEARCH BULLETIN

Origin of New Glial Cells in Intact and Injured Adult Spinal Cord

(2010) Fanie Barnabé-Heider et al.   Cell Stem Cell

Neuronal intrinsic barriers for axon regeneration in the adult CNS

(2010) Fang Sun et al.   CURRENT OPINION IN NEUROBIOLOGY

Extensive spontaneous plasticity of corticospinal projections after primate spinal cord injury

(2010) Ephron S Rosenzweig et al.   NATURE NEUROSCIENCE

Guidance Molecules in Axon Regeneration

(2010) R. J. Giger et al.   Cold Spring Harbor Perspectives in Biology

The bright side of the glial scar in CNS repair

(2009) Asya Rolls et al.   NATURE REVIEWS NEUROSCIENCE

Combined Intrinsic and Extrinsic Neuronal Mechanisms Facilitate Bridging Axonal Regeneration One Year after Spinal Cord Injury

(2009) Ken Kadoya et al.   NEURON

Cellular organization of the central canal ependymal zone, a niche of latent neural stem cells in the adult mammalian spinal cord

(2009) L.K. Hamilton et al.   NEUROSCIENCE

PTP  Is a Receptor for Chondroitin Sulfate Proteoglycan, an Inhibitor of Neural Regeneration

(2009) Y. Shen et al.   SCIENCE

Nogo-66 Promotes the Differentiation of Neural Progenitors into Astroglial Lineage Cells through mTOR-STAT3 Pathway

(2008) Bin Wang et al.   PLoS One

Spinal Cord Injury Reveals Multilineage Differentiation of Ependymal Cells

(2008) Konstantinos Meletis et al.   PLOS BIOLOGY

CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure

(2007) Michael T. Fitch et al.   EXPERIMENTAL NEUROLOGY

Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury

(2007) Gregoire Courtine et al.   NATURE MEDICINE