Article
Polymer Science
Shiyu Wang, Li Ma, Shuang Wang, Yazhou Wang, Gongyan Liu, Haibo Wang
Summary: A polyurethane composite film with dual antibacterial effects has been prepared, which can generate reactive oxygen species (ROS) and exhibit broad-spectrum antibacterial activity. It shows potential as a multi-mode combined antibacterial agent.
Article
Chemistry, Multidisciplinary
Wenjing Li, Min Wu, Hang Jiang, Longhui Yang, Chao Liu, Xiao Gong
Summary: This study presents a facile synthetic approach to prepare environmentally friendly white fluorescent carbon dots/ZnO quantum dots composites through electrostatic force, which can be used for fabrication of high-performance white light-emitting diodes. The fluorescence emission spectra of the WLED devices cover a range from 425 nm to 750 nm, with a CIE chromaticity coordinate of (0.30, 0.34) and a color temperature of 7093 K.
CHEMICAL COMMUNICATIONS
(2022)
Article
Materials Science, Biomaterials
Bianca Gottardo, Andreza R. M. Zoccal, Taiza Maschio-Lima, Thiago H. Lemes, Mario H. Paziani, Marcia R. Von Zeska Kress, Tarcisio M. Perfecto, Margarete T. G. Almeida, Diogo P. Volanti
Summary: This study evaluates the fungicidal activity of nanocomposites based on reduced graphene oxide loaded with silver nanoparticles against dermatophytes and Candida species. The results show that the composite has a good inhibitory effect on various fungi and has no toxic effects on the experimental model.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2023)
Article
Agriculture, Multidisciplinary
Marie-Francoise Cochet, Florence Baron, Sylvie Bonnassie, Sophie Jan, Nadine Leconte, Julien Jardin, Valerie Briard-Bion, Michel Gautier, Simon C. Andrews, Catherine Guerin-Dubiard, Francoise Nau
Summary: Recent research has shown that egg white at 45 degrees C has powerful bactericidal activity against S. enterica serovar Enteritidis, partly due to two specific peptides. However, these peptides only contribute to part of the bactericidal activity, suggesting the presence of other yet to be determined antimicrobial factors.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Review
Food Science & Technology
Julie Legros, Sophie Jan, Sylvie Bonnassie, Michel Gautier, Thomas Croguennec, Stephane Pezennec, Marie-Francoise Cochet, Francoise Nau, Simon C. Andrews, Florence Baron
Summary: Eggs are a whole and affordable food source that strongly resist bacterial infection, primarily due to the defensive systems in the egg white. Iron deficiency mediated by ovotransferrin is believed to play a key role in inhibiting Salmonella infection in eggs, with additional antibacterial properties beyond iron-chelation. However, the full antimicrobial activity of ovotransferrin in egg white is influenced by various environmental factors, limiting the current understanding of its role in egg safety.
Article
Biochemistry & Molecular Biology
Roger Wallacy Guimaraes Oliveira, Jefferson Magalhaes de Oliveira, Francyellen Batista da Paz, Edvani Curti Muniz, Edmilson Miranda de Moura, Jean Claudio Santos Costa, Matheus Oliveira do Nascimento, Andre Luis Menezes Carvalho, Iluska Martins Pinheiro, Anderson Nogueira Mendes, Livia Alves Filgueiras, Paulo Ricardo de Souza, Carla Veronica Rodarte de Moura
Summary: Anadenanthera colubrina, also known as white angico, is a common tree in Brazil with potential for producing medical films. This study prepared films composed of white angico gum and chitosan mixed with an antimicrobial agent using the solvent casting method, and evaluated their physicochemical properties and release behavior. The results showed that the films exhibited good properties and antimicrobial effects.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Alberto Curcio, Aurore Van de Walle, Emilia Benassai, Aida Serrano, Nathalie Luciani, Nicolas Menguy, Bella B. Manshian, Ara Sargsian, Stefaan Soenen, Ana Espinosa, Ali Abou-Hassan, Claire Wilhelm
Summary: Despite potential adverse biological outcomes, the intracellular bioprocessing of CuS nanoparticles reshapes them into bioengineered nanostructures without compromising their photothermal function and therapeutic potential, as supported by synchrotron X-ray absorption spectroscopy measurements.
Article
Chemistry, Applied
Magda A. El-Bendary, Maysa E. Moharam, Shimaa R. Hamed, Samiha M. Abo El-Ola, Safaa K. H. Khalil, Marwa M. Mounier, Amira M. Roshdy, Mousa A. Allam
Summary: Aspergillus caespitosus-derived AgNPs synthesized using exo- and endo-filtrates exhibit antimicrobial activity and potential for biosynthesis in a simple, green, and cost-effective manner. The nanoparticles show non-cytotoxic effects on most cells, except for endo-AgNPs on MCF-7 breast carcinoma cells.
APPLIED ORGANOMETALLIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Shanmugavel Chinnathambi, Naoto Shirahata, Mahima Kumar, Subramani Karthikeyan, Katsuhiko Abe, Vaijayanthi Thangavel, Ganesh N. Pandian
Summary: In recent years, the field of nanomaterials has rapidly developed for various biological applications. However, the lack of knowledge about the interaction between nanomaterials and the biological microenvironment poses a challenge for their clinical application. This study investigated the conformation changes of human immunoglobulin G (IgG) upon interaction with silicon quantum dots functionalized with 1-decene, Pluronic-F127 (SiQD-De/F127 micelles) using various techniques. The results demonstrated strong binding between SiQD-De/F127 micelles and IgG, and showed enhanced uptake and minimal cytotoxicity in cell lines and medaka fish. This study suggests that engineered quantum dots can maintain protein conformation and exhibit good bioefficacy.
Article
Chemistry, Multidisciplinary
Lukasz Richter, Corey Alfred Stevens, Paulo Jacob Silva, Laura Roset Julia, Carla Malinverni, Lixia Wei, Marcin Los, Francesco Stellacci
Summary: This study presents a novel compound that can irreversibly deactivate bacteriophages, safe for bacteria and mammalian cells, and can be applied directly in the environment of bioreactors, providing an effective method to prevent and control bacteriophage infections.
Article
Food Science & Technology
Eleana Sarantidi, Alexandra Ainatzoglou, Christine Papadimitriou, Eleni Stamoula, Katerina Maghiorou, Argyro Miflidi, Antonia Trichopoulou, Konstantinos C. Mountzouris, Athanasios K. Anagnostopoulos
Summary: The study exhaustively analyzed the proteome of egg white and yolk, revealing 371 and 428 new proteins in each, respectively. From a bioactivity standpoint, egg white and yolk proteins showed high enrichment for antioxidant and anti-inflammatory processes, as well as significance in apoptosis and focal adhesion pathways.
Article
Biochemistry & Molecular Biology
Maria Mondejar-Lopez, Alberto Jose Lopez-Jimenez, Joaquin C. Garcia Martinez, Oussama Ahrazem, Lourdes Gomez-Gomez, Enrique Niza
Summary: In this study, the natural terpene thymoquinone was encapsulated in chitosan nanoparticles, showing high antimicrobial and moisturizing properties in cosmetic products, indicating its promising use as an alternative preservative.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Nanoscience & Nanotechnology
Lutfur Rahman, Yasra Sarwar, Shazia Khaliq, Wasim Inayatullah, Wasim Abbas, Ameena Mobeen, Ata Ullah, Syed Zajif Hussain, Waheed S. Khan, Maria-Eleni Kyriazi, Irshad Hussain, Antonios G. Kanaras, Asma Rehman
Summary: In this study, surfactin-coated silver nanoparticles were synthesized and applied for the first time as an efficient antibacterial and antibiofilm agent against drug-resistant bacteria. The nanoparticles showed excellent bactericidal and antibiofilm activity against Pseudomonas aeruginosa, without causing significant dermal irritation or inflammation in vivo. Microscopic analysis also revealed no pathological alterations at the applied concentrations, supporting the potential use of these nanoparticles in combating drug-resistant bacterial biofilms and for skin wound dressings.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Review
Biochemistry & Molecular Biology
Mohamed E. Abd El-Hack, Maria Cristina de Oliveira, Youssef A. Attia, Mahmoud Kamal, Najlaa H. Almohmadi, Islam M. Youssef, Norhan E. Khalifa, Mahmoud Moustafa, Mohammed Al-Shehri, Ayman E. Taha
Summary: Global production of poultry products has increased rapidly, reflecting the low cost and consumer demand. Natural feed additives like polyphenols are popular, but high quantities may have negative effects on poultry health and egg quality.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Andrea Bernardos, Matej Bozik, Ana Montero, Edgar Perez-Esteve, Esther Garcia-Casado, Miloslav Lhotka, Adela Frankova, Maria Dolores Marcos, Jose Manuel Barat, Ramon Martinez-Manez, Pavel Kloucek
Summary: This study prepared biomimetic systems for the controlled release of eugenol inspired by natural plant defense mechanisms, and described their antifungal activity. Compared to systems capped with saccharides, maltodextrin- and maltose-capped systems release less eugenol in the absence of Aspergillus niger fungus but deliver more in its presence.
Article
Nanoscience & Nanotechnology
Yixin Wang, Fei Lu, Enling Hu, Kun Yu, Jiwei Li, Rong Bao, Fangyin Dai, Guangqian Lan, Ruiqi Xie
Summary: The study developed a transparent, porous, and elastic PADM by using a CaCl2-ethanol-H2O solution combined with an additional enzyme treatment. Changes in fiber organization and secondary structural changes in collagen were observed after treatment. The biocompatible PADM significantly expedited wound repair in vivo.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Nanoscience & Nanotechnology
Bitao Lu, Enling Hu, Ruiqi Xie, Kun Yu, Fei Lu, Rong Bao, Chenhui Wang, Guangqian Lan, Fangyin Dai
Summary: The study presents an all-in-one hollow nanoworm with exceptional magnetic-targeting ability and photothermal therapeutic effect, which can be precisely delivered to infection sites for highly effective bacterial elimination. It offers a novel approach for eradicating abscesses in the body by combining magnetic guidance therapy and near-infrared-triggered in situ generation of NO gas.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Materials Science, Paper & Wood
Zhen Yuan, Junwen Cheng, Guangqian Lan, Fei Lu
Summary: Antibacterial and moisturizing dressings were fabricated using cellulose/konjac glucomannan/Ag nanoparticle composites, with properties easily manipulated by adjusting composition ratios. The CK7-Ag3 aerogel showed excellent antibacterial activity and biocompatibility, enabling complete wound recovery within just 14 days.
Article
Engineering, Environmental
Zhenghui Shi, Guangqian Lan, Enling Hu, Fei Lu, Ping Qian, Jiawei Liu, Fangyin Dai, Ruiqi Xie
Summary: A magnetic field-guided hemostat has been developed for precise and instant hemorrhage control of complex bleeding wounds, demonstrating excellent biosafety through systematic assessments.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Engineering, Environmental
Ying Li, Yi Zhang, Yixin Wang, Kun Yu, Enling Hu, Fei Lu, Songmin Shang, Ruiqi Xie, Guangqian Lan
Summary: Inspired by the hierarchical structure of sugarcane, a self-draining sugarcane stem-based dressing was fabricated for removing exudates from overhydrated wounds, facilitating accelerated wound healing through plant transpiration mimicry and photothermal responsiveness. The dressing showed high evaporation efficiency and antibacterial properties, providing effective thermal insulation for wound protection. This study may offer a new strategy for versatile and efficient self-draining dressings for exudate management and wound healing using sustainable green resources.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Engineering, Biomedical
Bitao Lu, Enling Hu, Ruiqi Xie, Kun Yu, Fei Lu, Rong Bao, Chenhui Wang, Guangqian Lan, Fangyin Dai
Summary: Inspired by torpedoes, researchers developed a novel strategy to deliver hemostats into deep wounds using microcluster colloidosomes equipped with magnetic-mediated navigation and blast systems. The study demonstrated rapid and effective hemostasis in a vase-type hemorrhage model, and also showed excellent biodegradability in vivo.
BIOACTIVE MATERIALS
(2022)
Article
Multidisciplinary Sciences
Haoyu Qiu, Guangqian Lan, Weiwei Ding, Xinyu Wang, Wenyi Wang, Dahua Shou, Fei Lu, Enling Hu, Kun Yu, Songmin Shang, Ruiqi Xie
Summary: This study developed a Janus particle, SEC-Fe@CaT, that achieved rapid hemostasis in complex and deep wounds. The particle utilized bubble-driving and magnetic field-mediated forces to diffuse in the blood and access deep bleeding sites. Animal tests showed that SEC-Fe@CaT significantly reduced bleeding time compared to a commercial product.
Article
Materials Science, Multidisciplinary
Qing Li, Enling Hu, Kun Yu, Ruiqi Xie, Fei Lu, Bitao Lu, Rong Bao, Fangyin Dai, Guangqian Lan
Summary: Here, a filter pump-like hierarchical porous-structure (HPS) dressing is developed using konjac glucomannan (KGM) aerogel, bi-functional microporous starch (BMS), and a non-woven substrate for efficient hemostasis and wound management. The KGM aerogel intercalates into the non-woven network structure, forming a hydrophilic frame, while the BMS surface fills the spaces of the KGM frame, isolating and aggregating blood cells to establish rapid hemostasis. The HPS dressing demonstrates reliable hemostatic capacity, antibacterial properties, and enables wound healing within 2 weeks.
ADVANCED FIBER MATERIALS
(2023)
Article
Chemistry, Applied
Qian Xu, Enling Hu, Haoyu Qiu, Lu Liu, Qing Li, Bitao Lu, Kun Yu, Fei Lu, Ruiqi Xie, Guangqian Lan, Yuansong Zhang
Summary: Uncontrolled bleeding is a major cause of death, and the risk of bleeding from coagulopathy is even higher. A Janus hemostatic patch (PCMC/CCS) with a two-layer structure has been developed to treat bleeding in coagulopathy patients by infusing coagulation factors.
CARBOHYDRATE POLYMERS
(2023)
Article
Biochemistry & Molecular Biology
Lu Liu, Enling Hu, Haoyu Qiu, Qian Xu, Kun Yu, Ruiqi Xie, Fei Lu, Qi Wang, Bitao Lu, Qing Li, Guangqian Lan
Summary: Proposed a multifunctional silk gel that forms strong adhesions to tissue, has excellent mechanical properties, and delivers growth factors to the wound.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Multidisciplinary Sciences
Bitao Lu, Enling Hu, Weiwei Ding, Wenyi Wang, Ruiqi Xie, Kun Yu, Fei Lu, Guangqian Lan, Fangyin Dai
Summary: Inspired by bombardier beetles, a shape-memory aerogel with an aligned microchannel structure was developed for efficient hemostasis during emergency trauma. The aerogel exhibited remarkable hemostatic performance in severely bleeding wounds in a swine model and showed good degradability and biocompatibility, suggesting its potential for clinical application in humans.
Article
Materials Science, Biomaterials
Guofang Zhou, Fei Lu, Songmin Shang, Dahua Shou, Wenyi Wang, Kun Yu, Ruiqi Xie, Guangqian Lan, Enling Hu
Summary: A gas-jet propelled powder hemostat ((COL/PS)(4)@CaCO3-T-TXA(+)) has been developed to achieve rapid and targeted hemostasis in complex bleeding wounds. Animal studies showed that (COL/PS)(4)@CaCO3-T-TXA(+) had better hemostatic effects than the commercial product Celox(TM) in rabbit hepatic hemorrhage models, with bleeding stopping within 30 seconds.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Biochemistry & Molecular Biology
Yixin Wang, Haoyu Wang, Bitao Lu, Kun Yu, Ruiqi Xie, Guangqian Lan, Jing Xie, Enling Hu, Fei Lu
Summary: This paper presents a sandwich-like fibers/sponge dressing with continuous exudate drainage for optimal wound healing. Animal experiments showed that the dressing had superior wound-healing characteristics and has the potential to become the next generation of clinical dressings.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Suya Deng, Yinggui Huang, Enling Hu, Liang-Ju Ning, Ruiqi Xie, Kun Yu, Fei Lu, Guangqian Lan, Bitao Lu
Summary: A hierarchical 3D sponge based on chitosan/silk fibroin nanofibers was developed, which integrates cascade reactors to facilitate exudate transfer and wound microenvironment modulation. The sponge demonstrates exceptional exudate absorption capacity and antibacterial activity, making it an effective tool for accelerating diabetic wound healing.
CARBOHYDRATE POLYMERS
(2023)
Review
Materials Science, Biomaterials
Lu Liu, Enling Hu, Kun Yu, Ruiqi Xie, Fei Lu, Bitao Lu, Rong Bao, Qing Li, Fangyin Dai, Guangqian Lan
Summary: Traumatic hemorrhage can be fatal, especially with large blood loss in a short period. Hemostasis is crucial in emergency treatment, with a variety of natural and synthetic materials available for severe external trauma. Advances in hemostatic materials continue to improve, addressing current issues related to trauma bleeding and proposing future prospects.
BIOMATERIALS SCIENCE
(2021)