Release of IL-6 After Stroke Contributes to Impaired Cerebral Autoregulation and Hippocampal Neuronal Necrosis Through NMDA Receptor Activation and Upregulation of ET-1 and JNK
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Title
Release of IL-6 After Stroke Contributes to Impaired Cerebral Autoregulation and Hippocampal Neuronal Necrosis Through NMDA Receptor Activation and Upregulation of ET-1 and JNK
Authors
Keywords
Cerebral circulation, Inflammatory mediators, Plasminogen activators, Signal transduction, Ischemia
Journal
Translational Stroke Research
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2018-02-23
DOI
10.1007/s12975-018-0617-z
References
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Note: Only part of the references are listed.- tPA variant tPA-A296-299 Prevents impairment of cerebral autoregulation and necrosis of hippocampal neurons after stroke by inhibiting upregulation of ET-1
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- Norepinephrine Protects Cerebral Autoregulation and Reduces Hippocampal Necrosis after Traumatic Brain Injury via Blockade of ERK MAPK and IL-6 in Juvenile Pigs
- (2016) William M. Armstead et al. JOURNAL OF NEUROTRAUMA
- Tissue-Type Plasminogen Activator-A 296–299 Prevents Impairment of Cerebral Autoregulation After Stroke Through Lipoprotein-Related Receptor–Dependent Increase in cAMP and p38
- (2016) William M. Armstead et al. STROKE
- IL-1β, TNF-α, and IL-6 levels in gingival fluid and serum of patients with ischemic stroke
- (2016) Anna Wytrykowska et al. Journal of Oral Science
- A Novel Small-Molecule Inhibitor Targeting the IL-6 Receptor β Subunit, Glycoprotein 130
- (2015) Soon-Sun Hong et al. JOURNAL OF IMMUNOLOGY
- Inhibition of reactive oxygen species downregulates the MAPK pathway in rat spinal cord after limb ischemia reperfusion injury
- (2015) Eun Kyung Choi et al. International Journal of Surgery
- Targeting interleukin-6 in inflammatory autoimmune diseases and cancers
- (2013) Xin Yao et al. PHARMACOLOGY & THERAPEUTICS
- tPA contributes to impaired NMDA cerebrovasodilation after traumatic brain injury through activation of JNK MAPK
- (2011) William M Armstead et al. NEUROLOGICAL RESEARCH
- Regulation of Airway Contractility by Plasminogen Activators through N-Methyl-D-Aspartate Receptor–1
- (2010) Taher Nassar et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Signaling, delivery and age as emerging issues in the benefit/risk ratio outcome of tPA For treatment of CNS ischemic disorders
- (2010) William M. Armstead et al. JOURNAL OF NEUROCHEMISTRY
- Red blood cell-coupled tissue plasminogen activator prevents impairment of cerebral vasodilatory responses through inhibition of c-Jun-N-terminal kinase and potentiation of p38 mitogen-activated protein kinase after cerebral photothrombosis in the newborn pig
- (2010) William M. Armstead et al. Pediatric Critical Care Medicine
- Young Age as a Risk Factor for Impaired Cerebral Autoregulation after Moderate to Severe Pediatric Traumatic Brain Injury
- (2009) Serena S. Freeman et al. ANESTHESIOLOGY
- Key role of tissue plasminogen activator in neurovascular coupling
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