Membrane Repair Mechanisms against Permeabilization by Pore-Forming Toxins

Phospholipase A activity of adenylate cyclase toxin mediates translocation of its adenylate cyclase domain

(2017) David González-Bullón et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repair of a Bacterial Small β-Barrel Toxin Pore Depends on Channel Width

(2017) Gisela von Hoven et al.   mBio

High-Throughput Microplate-Based Assay to Monitor Plasma Membrane Wounding and Repair

(2017) Sarika Pathak-Sharma et al.   Frontiers in Cellular and Infection Microbiology

Stability, structural and functional properties of a monomeric, calcium–loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis

(2017) Sara E. Cannella et al.   Scientific Reports

Protein–lipid interactions and non-lamellar lipidic structures in membrane pore formation and membrane fusion

(2016) Robert J.C. Gilbert   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Active release of pneumolysin prepores and pores by mammalian cells undergoing a Streptococcus pneumoniae attack

(2016) Heidi Wolfmeier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

An actin-dependent annexin complex mediates plasma membrane repair in muscle

(2016) Alexis R. Demonbreun et al.   JOURNAL OF CELL BIOLOGY

Cryo-EM structure of aerolysin variants reveals a novel protein fold and the pore-formation process

(2016) Ioan Iacovache et al.   Nature Communications

Plasma Membrane Repair Is Regulated Extracellularly by Proteases Released from Lysosomes

(2016) Thiago Castro-Gomes et al.   PLoS One

Negatively charged residues of the segment linking the enzyme and cytolysin moieties restrict the membrane-permeabilizing capacity of adenylate cyclase toxin

(2016) Jiri Masin et al.   Scientific Reports

Ca2+-dependent repair of pneumolysin pores: A new paradigm for host cellular defense against bacterial pore-forming toxins

(2015) Heidi Wolfmeier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Phobalysin, a Small β-Pore-Forming Toxin of Photobacterium damselae subsp. damselae

(2015) Amable J. Rivas et al.   INFECTION AND IMMUNITY

Defying death: Cellular survival strategies following plasmalemmal injury by bacterial toxins

(2015) Eduard B. Babiychuk et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Physico-chemical and biological considerations for membrane wound evolution and repair in animal cells

(2015) Ana Joaquina Jimenez et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Microvesicle Shedding and Lysosomal Repair Fulfill Divergent Cellular Needs during the Repair of Streptolysin O-Induced Plasmalemmal Damage

(2014) Alexander P. Atanassoff et al.   PLoS One

ESCRT Machinery Is Required for Plasma Membrane Repair

(2014) A. J. Jimenez et al.   SCIENCE

Damage control: cellular mechanisms of plasma membrane repair

(2014) Norma W. Andrews et al.   TRENDS IN CELL BIOLOGY

Mechanism of Ca2+-triggered ESCRT assembly and regulation of cell membrane repair

(2014) Luana L. Scheffer et al.   Nature Communications

Characterization of a Membrane-active Peptide from theBordetella pertussisCyaA Toxin

(2013) Orso Subrini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caveolae internalization repairs wounded cells and muscle fibers

(2013) Matthias Corrotte et al.   eLife

Live Imaging Assay for Assessing the Roles of Ca2+ and Sphingomyelinase in the Repair of Pore-forming Toxin Wounds

(2013) Christina Tam et al.   Jove-Journal of Visualized Experiments

Pathogenic Pore-Forming Proteins: Function and Host Response

(2012) Mirko Bischofberger et al.   Cell Host & Microbe

Aggregatibacter actinomycetemcomitans leukotoxin cytotoxicity occurs through bilayer destabilization

(2012) Angela C. Brown et al.   CELLULAR MICROBIOLOGY

Use the force: membrane tension as an organizer of cell shape and motility

(2012) Alba Diz-Muñoz et al.   TRENDS IN CELL BIOLOGY

Membrane assembly of the cholesterol-dependent cytolysin pore complex

(2011) Eileen M. Hotze et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

RAB-5- and RAB-11-Dependent Vesicle-Trafficking Pathways Are Required for Plasma Membrane Repair after Attack by Bacterial Pore-Forming Toxin

(2011) Ferdinand C.O. Los et al.   Cell Host & Microbe

Pore-forming toxins induce multiple cellular responses promoting survival

(2011) Manuel R. Gonzalez et al.   CELLULAR MICROBIOLOGY

Tailored Protection against Plasmalemmal Injury by Annexins with Different Ca2+Sensitivities

(2011) Sarah Potez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Streptolysin O clearance through sequestration into blebs that bud passively from the plasma membrane

(2011) P. A. Keyel et al.   JOURNAL OF CELL SCIENCE

Toxin Pores Endocytosed During Plasma Membrane Repair Traffic into the Lumen of MVBs for Degradation

(2011) Matthias Corrotte et al.   TRAFFIC

Annexin-A5 assembled into two-dimensional arrays promotes cell membrane repair

(2011) Anthony Bouter et al.   Nature Communications

Global Functional Analyses of Cellular Responses to Pore-Forming Toxins

(2011) Cheng-Yuan Kao et al.   PLoS Pathogens

Pertussis toxin and adenylate cyclase toxin: key virulence factors ofBordetella pertussisand cell biology tools

(2010) Nicholas H Carbonetti   Future Microbiology

Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair

(2010) Christina Tam et al.   JOURNAL OF CELL BIOLOGY

Pore-forming toxins activate MAPK p38 by causing loss of cellular potassium

(2009) Nicole Kloft et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis

(2009) J. Thiery et al.   BLOOD

Intracellular Ca2+ operates a switch between repair and lysis of streptolysin O-perforated cells

(2009) E B Babiychuk et al.   CELL DEATH AND DIFFERENTIATION

The annexins: spatial and temporal coordination of signaling events during cellular stress

(2009) Katia Monastyrskaya et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Membrane injury by pore-forming proteins

(2009) Mirko Bischofberger et al.   CURRENT OPINION IN CELL BIOLOGY

Oligomerization is involved in pore formation by Bordetella adenylate cyclase toxin

(2009) Jana Vojtova-Vodolanova et al.   FASEB JOURNAL

Elimination of a bacterial pore-forming toxin by sequential endocytosis and exocytosis

(2008) Matthias Husmann et al.   FEBS LETTERS

Repair of injured plasma membrane by rapid Ca2+-dependent endocytosis

(2008) Vincent Idone et al.   JOURNAL OF CELL BIOLOGY