TMEM43-S358L mutation enhances NF-κB-TGFβ signal cascade in arrhythmogenic right ventricular dysplasia/cardiomyopathy

TGF-β/SMAD Pathway and Its Regulation in Hepatic Fibrosis

(2016) Fengyun Xu et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Catalpol reduces the production of inflammatory mediators via PPAR-γ activation in human intestinal Caco-2 cells

(2016) Kyoung Sik Park   Journal of Natural Medicines

TGF-β: the master regulator of fibrosis

(2016) Xiao-ming Meng et al.   Nature Reviews Nephrology

TMEM43/LUMA is a key signaling component mediating EGFR-induced NF-κB activation and tumor progression

(2016) C Jiang et al.   ONCOGENE

Chop deficiency prevents UUO-induced renal fibrosis by attenuating fibrotic signals originated from Hmgb1/TLR4/NFκB/IL-1β signaling

(2015) M Zhang et al.   Cell Death & Disease

The TMEM43 Newfoundland mutation p.S358L causing ARVC-5 was imported from Europe and increases the stiffness of the cell nucleus

(2014) H. Milting et al.   EUROPEAN HEART JOURNAL

Protein extracts of Crassostrea gigas alleviate CCl4-induced hepatic fibrosis in rats by reducing the expression of CTGF, TGF-β1 and NF-κB in liver tissues

(2014) JUE ZHOU et al.   Molecular Medicine Reports

Epithelial Growth Factor Receptor–Activated Nuclear Factor κB Signaling and Its Role in Epithelial Growth Factor Receptor–Associated Tumors

(2013) Deng Pan et al.   CANCER JOURNAL

TMEM43 mutations associated with arrhythmogenic right ventricular cardiomyopathy in non-Newfoundland populations

(2013) Berivan Baskin et al.   HUMAN GENETICS

The natural history of a genetic subtype of arrhythmogenic right ventricular cardiomyopathy caused by a p.S358L mutation in TMEM43

(2012) KA Hodgkinson et al.   CLINICAL GENETICS

Recurrent missense mutations in TMEM43 (ARVD5) due to founder effects cause arrhythmogenic cardiomyopathies in the UK and Canada

(2012) Annika F.M. Haywood et al.   EUROPEAN HEART JOURNAL

Sulfasalazine prevents the increase in TGF-β, COX-2, nuclear NFκB translocation and fibrosis in CCl4-induced liver cirrhosis in the rat

(2012) E Chávez et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Regulation of NF-κB by the CARD proteins

(2012) Changying Jiang et al.   IMMUNOLOGICAL REVIEWS

Arrhythmogenic right ventricular cardiomyopathy: severe structural alterations are associated with inflammation

(2012) Oscar Campuzano et al.   JOURNAL OF CLINICAL PATHOLOGY

Myofibroblast-mediated mechanisms of pathological remodelling of the heart

(2012) Karl T. Weber et al.   Nature Reviews Cardiology

Nuclear Plakoglobin Is Essential for Differentiation of Cardiac Progenitor Cells to Adipocytes in Arrhythmogenic Right Ventricular Cardiomyopathy

(2011) Raffaella Lombardi et al.   CIRCULATION RESEARCH

Altered Desmosomal Proteins in Granulomatous Myocarditis and Potential Pathogenic Links to Arrhythmogenic Right Ventricular Cardiomyopathy

(2011) Angeliki Asimaki et al.   Circulation-Arrhythmia and Electrophysiology

Arrhythmogenic Cardiomyopathy

(2011) Kalliopi Pilichou et al.   Circulation-Cardiovascular Genetics

Mutation analysis and evaluation of the cardiac localization of TMEM43 in arrhythmogenic right ventricular cardiomyopathy

(2011) AH Christensen et al.   CLINICAL GENETICS

Cardiac Tissue-Restricted Deletion of Plakoglobin Results in Progressive Cardiomyopathy and Activation of  -Catenin Signaling

(2011) J. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

Arritmias y enfermedades del corazón derecho: de las bases genéticas a la clínica

(2011) Lucio Capulzini et al.   REVISTA ESPANOLA DE CARDIOLOGIA

Assessment of inflammation in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia

(2010) Maria E. Campian et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

PPAR-γ Activation As an Anti-inflammatory Therapy for Respiratory Virus Infections

(2010) Josep Bassaganya-Riera et al.   VIRAL IMMUNOLOGY

Arrhythmogenic Right Ventricular Cardiomyopathy Type 5 Is a Fully Penetrant, Lethal Arrhythmic Disorder Caused by a Missense Mutation in the TMEM43 Gene

(2008) Nancy D. Merner et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

LUMA interacts with emerin and influences its distribution at the inner nuclear membrane

(2008) Luiza Bengtsson et al.   JOURNAL OF CELL SCIENCE

Arrhythmogenic Right Ventricular Dysplasia

(2008) Palaniappan Muthappan et al.   PROGRESS IN CARDIOVASCULAR DISEASES