Interleukin-4 activated macrophages mediate immunity to filarial helminth infection by sustaining CCR3-dependent eosinophilia

Myeloid cell recruitment versus local proliferation differentiates susceptibility from resistance to filarial infection

(2018) Sharon M Campbell et al.   eLife

Local amplifiers of IL-4Rα–mediated macrophage activation promote repair in lung and liver

(2017) Carlos M. Minutti et al.   SCIENCE

IL-33 delivery induces serous cavity macrophage proliferation independent of interleukin-4 receptor alpha

(2016) Lucy H. Jackson-Jones et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cystatin F Ensures Eosinophil Survival by Regulating Granule Biogenesis

(2016) Stephen P. Matthews et al.   IMMUNITY

Long-lived self-renewing bone marrow-derived macrophages displace embryo-derived cells to inhabit adult serous cavities

(2016) Calum C. Bain et al.   Nature Communications

Eosinophils and IL-4 Support Nematode Growth Coincident with an Innate Response to Tissue Injury

(2015) Lu Huang et al.   PLoS Pathogens

Immune Antibodies and Helminth Products Drive CXCR2-Dependent Macrophage-Myofibroblast Crosstalk to Promote Intestinal Repair

(2015) Julia Esser-von Bieren et al.   PLoS Pathogens

Alternatively activated macrophages derived from monocytes and tissue macrophages are phenotypically and functionally distinct

(2014) U. M. Gundra et al.   BLOOD

Macrophage proliferation, provenance, and plasticity in macroparasite infection

(2014) Dominik Rückerl et al.   IMMUNOLOGICAL REVIEWS

Dynamic Changes in Macrophage Activation and Proliferation during the Development and Resolution of Intestinal Inflammation

(2014) Matthew C. Little et al.   JOURNAL OF IMMUNOLOGY

Eosinophils Mediate Protective Immunity against Secondary Nematode Infection

(2014) Lu Huang et al.   JOURNAL OF IMMUNOLOGY

Neutrophils prime a long-lived effector macrophage phenotype that mediates accelerated helminth expulsion

(2014) Fei Chen et al.   NATURE IMMUNOLOGY

A murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasis

(2014) Alice Halliday et al.   Parasites & Vectors

Eosinophils Are Important for Protection, Immunoregulation and Pathology during Infection with Nematode Microfilariae

(2014) Emma T. Cadman et al.   PLoS Pathogens

Ly6Chigh Monocytes Become Alternatively Activated Macrophages in Schistosome Granulomas with Help from CD4+ Cells

(2014) Natasha M. Girgis et al.   PLoS Pathogens

Human and Mouse Macrophages Collaborate with Neutrophils To Kill Larval Strongyloides stercoralis

(2013) Sandra Bonne-Année et al.   INFECTION AND IMMUNITY

Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages

(2013) Ari B. Molofsky et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The skin is an important bulwark of acquired immunity against intestinal helminths

(2013) Kazushige Obata-Ninomiya et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1

(2013) Stephen J. Jenkins et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: IL-25 Elicits Innate Lymphoid Type 2 and Type II NKT Cells That Regulate Obesity in Mice

(2013) E. Hams et al.   JOURNAL OF IMMUNOLOGY

GATA-1 regulates the generation and function of basophils

(2013) Y. Nei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibodies Trap Tissue Migrating Helminth Larvae and Prevent Tissue Damage by Driving IL-4Rα-Independent Alternative Differentiation of Macrophages

(2013) Julia Esser-von Bieren et al.   PLoS Pathogens

The biology of nematode- and IL4R -dependent murine macrophage polarization in vivo as defined by RNA-Seq and targeted lipidomics

(2012) G. D. Thomas et al.   BLOOD

Adoptive transfer of IL-4Rα+ macrophages is sufficient to enhance eosinophilic inflammation in a mouse model of allergic lung inflammation

(2012) Andrew Q Ford et al.   BMC IMMUNOLOGY

Granulocytes in Helminth Infection - Who is Calling the Shots?

(2012) B. L. Makepeace et al.   CURRENT MEDICINAL CHEMISTRY

An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection

(2012) Fei Chen et al.   NATURE MEDICINE

Alternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivo

(2012) P. C. Cook et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterising the Mucosal and Systemic Immune Responses to Experimental Human Hookworm Infection

(2012) Soraya Gaze et al.   PLoS Pathogens

Major Basic Protein from Eosinophils and Myeloperoxidase from Neutrophils Are Required for Protective Immunity to Strongyloides stercoralis in Mice

(2011) Amy E. O'Connell et al.   INFECTION AND IMMUNITY

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation

(2011) S. J. Jenkins et al.   SCIENCE

Multiple Helminth Infection of the Skin Causes Lymphocyte Hypo-Responsiveness Mediated by Th2 Conditioning of Dermal Myeloid Cells

(2011) Peter C. Cook et al.   PLoS Pathogens

Filarial Parasites Develop Faster and Reproduce Earlier in Response to Host Immune Effectors That Determine Filarial Life Expectancy

(2010) Simon A. Babayan et al.   PLOS BIOLOGY

Alternatively activated macrophage-derived RELM-α is a negative regulator of type 2 inflammation in the lung

(2009) Meera G. Nair et al.   JOURNAL OF EXPERIMENTAL MEDICINE