Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages

Vaccine-elicited memory CD4+ T cell expansion is impaired in the lungs during tuberculosis

(2017) Stephen M. Carpenter et al.   PLoS Pathogens

PPE38 Protein of Mycobacterium tuberculosis Inhibits Macrophage MHC Class I Expression and Dampens CD8+ T Cell Responses

(2017) Lu Meng et al.   Frontiers in Cellular and Infection Microbiology

Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform

(2017) Jeremy M. Rock et al.   Nature Microbiology

Comprehensive definition of human immunodominant CD8 antigens in tuberculosis

(2017) Deborah A. Lewinsohn et al.   npj Vaccines

Exosomes function in antigen presentation during an in vivo Mycobacterium tuberculosis infection

(2017) Victoria L. Smith et al.   Scientific Reports

Antigen Export Reduces Antigen Presentation and Limits T Cell Control of M. tuberculosis

(2016) Smita Srivastava et al.   Cell Host & Microbe

Role of Metal-Dependent Regulation of ESX-3 Secretion in Intracellular Survival of Mycobacterium tuberculosis

(2016) Emir Tinaztepe et al.   INFECTION AND IMMUNITY

Separable roles forMycobacterium tuberculosisESX-3 effectors in iron acquisition and virulence

(2016) JoAnn M. Tufariello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TB vaccines in clinical development

(2016) Ann M. Ginsberg et al.   TUBERCULOSIS

A Higher Activation Threshold of Memory CD8+ T Cells Has a Fitness Cost That Is Modified by TCR Affinity during Tuberculosis

(2016) Stephen M. Carpenter et al.   PLoS Pathogens

M. tuberculosis T Cell Epitope Analysis Reveals Paucity of Antigenic Variation and Identifies Rare Variable TB Antigens

(2015) Mireia Coscolla et al.   Cell Host & Microbe

Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines

(2015) Nadia Caccamo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection

(2015) Cláudio Nunes-Alves et al.   PLoS Pathogens

Cell-to-Cell Transfer of M. tuberculosis Antigens Optimizes CD4 T Cell Priming

(2014) Smita Srivastava et al.   Cell Host & Microbe

Beyond macrophages: the diversity of mononuclear cells in tuberculosis

(2014) Smita Srivastava et al.   IMMUNOLOGICAL REVIEWS

Tuberculosis Triggers a Tissue-Dependent Program of Differentiation and Acquisition of Effector Functions by Circulating Monocytes

(2014) M. Skold et al.   JOURNAL OF IMMUNOLOGY

CD8+ T Cells Are Activated in an Antigen-Independent Manner in HIV-Infected Individuals

(2014) S. Bastidas et al.   JOURNAL OF IMMUNOLOGY

Orchestration of pulmonary T cell immunity during Mycobacterium tuberculosis infection: Immunity interruptus

(2014) Samuel M. Behar et al.   SEMINARS IN IMMUNOLOGY

Antigens for CD4 and CD8 T Cells in Tuberculosis

(2014) C. S. Lindestam Arlehamn et al.   Cold Spring Harbor Perspectives in Medicine

iNKT Cell Production of GM-CSF Controls Mycobacterium tuberculosis

(2014) Alissa C. Rothchild et al.   PLoS Pathogens

Cutting Edge: Direct Recognition of Infected Cells by CD4 T Cells Is Required for Control of Intracellular Mycobacterium tuberculosis In Vivo

(2013) S. Srivastava et al.   JOURNAL OF IMMUNOLOGY

IL-1  Promotes Antimicrobial Immunity in Macrophages by Regulating TNFR Signaling and Caspase-3 Activation

(2013) P. Jayaraman et al.   JOURNAL OF IMMUNOLOGY

Generation of T cell receptor–retrogenic mice: improved retroviral-mediated stem cell gene transfer

(2013) Matthew L Bettini et al.   Nature Protocols

The ESX-3 Secretion System Is Necessary for Iron and Zinc Homeostasis in Mycobacterium tuberculosis

(2013) Agnese Serafini et al.   PLoS One

IFN-  from CD4 T Cells Is Essential for Host Survival and Enhances CD8 T Cell Function during Mycobacterium tuberculosis Infection

(2012) A. M. Green et al.   JOURNAL OF IMMUNOLOGY

Phagosomal Rupture by Mycobacterium tuberculosis Results in Toxicity and Host Cell Death

(2012) Roxane Simeone et al.   PLoS Pathogens

Tuberculosis and HIV Co-Infection

(2012) Andrzej Pawlowski et al.   PLoS Pathogens

Intravital Imaging Reveals Limited Antigen Presentation and T Cell Effector Function in Mycobacterial Granulomas

(2011) Jackson G. Egen et al.   IMMUNITY

Interleukins, from 1 to 37, and interferon-γ: Receptors, functions, and roles in diseases

(2011) Mübeccel Akdis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Solution Structure of theMycobacterium tuberculosisEsxG·EsxH Complex

(2011) Dariush Ilghari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

T cell receptor signal strength in Tregand iNKT cell development demonstrated by a novel fluorescent reporter mouse

(2011) Amy E. Moran et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Suboptimal Activation of Antigen-Specific CD4+ Effector Cells Enables Persistence of M. tuberculosis In Vivo

(2011) Tyler D. Bold et al.   PLoS Pathogens

High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism

(2011) Jennifer E. Griffin et al.   PLoS Pathogens

Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis

(2010) Shahin Shafiani et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mycobacterium tuberculosis Directs Immunofocusing of CD8+ T Cell Responses Despite Vaccination

(2010) J. S. Woodworth et al.   JOURNAL OF IMMUNOLOGY

Secreted Immunodominant Mycobacterium tuberculosis Antigens Are Processed by the Cytosolic Pathway

(2010) J. E. Grotzke et al.   JOURNAL OF IMMUNOLOGY

Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved

(2010) Iñaki Comas et al.   NATURE GENETICS

Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis

(2010) Maziar Divangahi et al.   NATURE IMMUNOLOGY

Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair

(2009) Maziar Divangahi et al.   NATURE IMMUNOLOGY

CD4 and CD8 T Cell Responses to the M. tuberculosis Ag85B-TB10.4 Promoted by Adjuvanted Subunit, Adenovector or Heterologous Prime Boost Vaccination

(2009) Tara Elvang et al.   PLoS One

Macrophage and T Cell Dynamics during the Development and Disintegration of Mycobacterial Granulomas

(2008) Jackson G. Egen et al.   IMMUNITY

Bacterial Protein Secretion Is Required for Priming of CD8+ T Cells Specific for the Mycobacterium tuberculosis Antigen CFP10

(2008) J. S. Woodworth et al.   INFECTION AND IMMUNITY

Delayed protection by ESAT-6–specific effector CD4+T cells after airborneM. tuberculosisinfection

(2008) Alena M. Gallegos et al.   JOURNAL OF EXPERIMENTAL MEDICINE

DM, but not cathepsin L, is required to control an aerosol infection with Mycobacterium tuberculosis

(2008) Rajeev Mani Nepal et al.   JOURNAL OF LEUKOCYTE BIOLOGY