Alphavirus-induced hyperactivation of PI3K/AKT directs pro-viral metabolic changes

Inflammation, metaflammation and immunometabolic disorders

(2017) Gökhan S. Hotamisligil   NATURE

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Effects of an In-Frame Deletion of the6kGene Locus from the Genome of Ross River Virus

(2016) Adam Taylor et al.   JOURNAL OF VIROLOGY

Akt inhibitors in cancer treatment: The long journey from drug discovery to clinical use (Review)

(2015) GEORGE MIHAI NITULESCU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Semliki Forest virus and Sindbis virus, but not vaccinia virus, require glycolysis for optimal replication

(2015) James S. Findlay et al.   JOURNAL OF GENERAL VIROLOGY

Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization

(2015) Bastian Thaa et al.   JOURNAL OF VIROLOGY

Viral activation of cellular metabolism

(2015) Erica L. Sanchez et al.   VIROLOGY

MYC-induced reprogramming of glutamine catabolism supports optimal virus replication

(2015) Minh Thai et al.   Nature Communications

Adenovirus E4ORF1-Induced MYC Activation Promotes Host Cell Anabolic Glucose Metabolism and Virus Replication

(2014) Minh Thai et al.   Cell Metabolism

A role for vaccinia virus protein C16 in reprogramming cellular energy metabolism

(2014) M. Mazzon et al.   JOURNAL OF GENERAL VIROLOGY

Vaccinia Virus Requires Glutamine but Not Glucose for Efficient Replication

(2014) K. A. Fontaine et al.   JOURNAL OF VIROLOGY

Dengue Virus Induces and Requires Glycolysis for Optimal Replication

(2014) Krystal A. Fontaine et al.   JOURNAL OF VIROLOGY

Kaposi's Sarcoma Herpesvirus MicroRNAs Induce Metabolic Transformation of Infected Cells

(2014) Ohad Yogev et al.   PLoS Pathogens

A systematic review of dual targeting in HER2-positive breast cancer

(2013) Iben Kümler et al.   CANCER TREATMENT REVIEWS

Role of Herpes Simplex Virus VP11/12 Tyrosine-Based Motifs in Binding and Activation of the Src Family Kinase Lck and Recruitment of p85, Grb2, and Shc

(2013) U. Strunk et al.   JOURNAL OF VIROLOGY

A study of Caenorhabditis elegans DAF-2 mutants by metabolomics and differential correlation networks

(2013) Cecilia Castro et al.   Molecular BioSystems

Role for the Phosphatidylinositol 3-Kinase-Akt-TOR Pathway during Sindbis Virus Replication in Arthropods

(2012) R. K. Patel et al.   JOURNAL OF VIROLOGY

Accumulation of Autophagosomes in Semliki Forest Virus-Infected Cells Is Dependent on Expression of the Viral Glycoproteins

(2012) K. E. Eng et al.   JOURNAL OF VIROLOGY

Sindbis virus replication, is insensitive to rapamycin and torin1, and suppresses Akt/mTOR pathway late during infection in HEK cells

(2011) Vidyarani Mohankumar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SH3 Domain-Mediated Recruitment of Host Cell Amphiphysins by Alphavirus nsP3 Promotes Viral RNA Replication

(2011) Maarit Neuvonen et al.   PLoS Pathogens

Divergent Effects of Human Cytomegalovirus and Herpes Simplex Virus-1 on Cellular Metabolism

(2011) Livia Vastag et al.   PLoS Pathogens

Phosphatidylinositol 3-Kinase-, Actin-, and Microtubule-Dependent Transport of Semliki Forest Virus Replication Complexes from the Plasma Membrane to Modified Lysosomes

(2010) P. Spuul et al.   JOURNAL OF VIROLOGY

MK-2206, an Allosteric Akt Inhibitor, Enhances Antitumor Efficacy by Standard Chemotherapeutic Agents or Molecular Targeted Drugs In vitro and In vivo

(2010) H. Hirai et al.   MOLECULAR CANCER THERAPEUTICS

Hepatitis C Virus-Linked Mitochondrial Dysfunction Promotes Hypoxia-Inducible Factor 1 -Mediated Glycolytic Adaptation

(2009) M. Ripoli et al.   JOURNAL OF VIROLOGY

Construction, properties, and potential application of infectious plasmids containing Semliki Forest virus full-length cDNA with an inserted intron

(2007) Liane Ülper et al.   JOURNAL OF VIROLOGICAL METHODS