Loss of CXCR6 coreceptor usage characterizes pathogenic lentiviruses

Phyloepidemiological Analysis Reveals that Viral Divergence Led to the Paucity of Simian Immunodeficiency Virus SIVmus/gsn/mon Infections in Wild Populations

(2017) Fabian Schmidt et al.   JOURNAL OF VIROLOGY

Effective treatment of SIVcpz-induced immunodeficiency in a captive western chimpanzee

(2017) Hannah J. Barbian et al.   Retrovirology

Modern-day SIV viral diversity generated by extensive recombination and cross-species transmission

(2017) Sidney M. Bell et al.   PLoS Pathogens

CXCR6-Mediated Simian Immunodeficiency Virus SIVagmSab Entry into Sabaeus African Green Monkey Lymphocytes Implicates Widespread Use of Non-CCR5 Pathways in Natural Host Infections

(2016) Katherine S. Wetzel et al.   JOURNAL OF VIROLOGY

Immune activation in HIV infection

(2016) Mickaël J. Ploquin et al.   Current Opinion in HIV and AIDS

Dualtropic CXCR6/CCR5 Simian Immunodeficiency Virus (SIV) Infection of Sooty Mangabey Primary Lymphocytes: Distinct Coreceptor Use in Natural versus Pathogenic Hosts of SIV

(2015) Sarah T. C. Elliott et al.   JOURNAL OF VIROLOGY

Neutralization Properties of Simian Immunodeficiency Viruses Infecting Chimpanzees and Gorillas

(2015) Hannah J. Barbian et al.   mBio

Divergent CD4+ T Memory Stem Cell Dynamics in Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infections

(2014) E. K. Cartwright et al.   JOURNAL OF IMMUNOLOGY

Great ape genetic diversity and population history

(2013) Javier Prado-Martinez et al.   NATURE

Origins of HIV and the AIDS Pandemic

(2013) P. M. Sharp et al.   Cold Spring Harbor Perspectives in Medicine

HIV Pathogenesis: The Host

(2013) A. A. Lackner et al.   Cold Spring Harbor Perspectives in Medicine

Differential infection patterns of CD4+ T cells and lymphoid tissue viral burden distinguish progressive and nonprogressive lentiviral infections

(2012) J. M. Brenchley et al.   BLOOD

Efficient SIVcpz replication in human lymphoid tissue requires viral matrix protein adaptation

(2012) Frederic Bibollet-Ruche et al.   JOURNAL OF CLINICAL INVESTIGATION

Lineage-Specific Differences between Human and Simian Immunodeficiency Virus Regulation of gp120 Trimer Association and CD4 Binding

(2012) A. Finzi et al.   JOURNAL OF VIROLOGY

Eastern Chimpanzees, but Not Bonobos, Represent a Simian Immunodeficiency Virus Reservoir

(2012) Y. Li et al.   JOURNAL OF VIROLOGY

A Species-Specific Amino Acid Difference in the Macaque CD4 Receptor Restricts Replication by Global Circulating HIV-1 Variants Representing Viruses from Recent Infection

(2012) D. Humes et al.   JOURNAL OF VIROLOGY

Cloning and Analysis of Sooty Mangabey Alternative Coreceptors That Support Simian Immunodeficiency Virus SIVsmm Entry Independently of CCR5

(2011) S. T. C. Elliott et al.   JOURNAL OF VIROLOGY

Low levels of SIV infection in sooty mangabey central memory CD4+ T cells are associated with limited CCR5 expression

(2011) Mirko Paiardini et al.   NATURE MEDICINE

A Novel CCR5 Mutation Common in Sooty Mangabeys Reveals SIVsmm Infection of CCR5-Null Natural Hosts and Efficient Alternative Coreceptor Use In Vivo

(2010) Nadeene E. Riddick et al.   PLoS Pathogens

Extensive survey on the prevalence and genetic diversity of SIVs in primate bushmeat provides insights into risks for potential new cross-species transmissions

(2009) Avelin F. Aghokeng et al.   INFECTION GENETICS AND EVOLUTION

Patterns of Diversity in HIV-Related Loci among Subspecies of Chimpanzee: Concordance at CCR5 and Differences at CXCR4 and CX3CR1

(2009) T.S. MacFie et al.   MOLECULAR BIOLOGY AND EVOLUTION

Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz

(2009) Brandon F. Keele et al.   NATURE

CD4 downregulation by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection

(2009) Coreen M Beaumier et al.   NATURE MEDICINE

Critical Loss of the Balance between Th17 and T Regulatory Cell Populations in Pathogenic SIV Infection

(2009) David Favre et al.   PLoS Pathogens

Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

(2008) J. M. Brenchley et al.   BLOOD

Simian Immunodeficiency Virus SIVagm Dynamics in African Green Monkeys

(2008) I. Pandrea et al.   JOURNAL OF VIROLOGY

Short-Lived Infected Cells Support Virus Replication in Sooty Mangabeys Naturally Infected with Simian Immunodeficiency Virus: Implications for AIDS Pathogenesis

(2008) S. N. Gordon et al.   JOURNAL OF VIROLOGY

Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques

(2008) V Cecchinato et al.   Mucosal Immunology

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols