BMP signaling downstream of the Highwire E3 ligase sensitizes nociceptors

Serotonergic Modulation Enables Pathway-Specific Plasticity in a Developing Sensory Circuit in Drosophila

(2017) Takuya Kaneko et al.   NEURON

The PHR proteins: intracellular signaling hubs in neuronal development and axon degeneration

(2016) Brock Grill et al.   Neural Development

Nociceptor-Enriched Genes Required for Normal Thermal Nociception

(2016) Ken Honjo et al.   Cell Reports

A Novel, Noncanonical BMP Pathway Modulates Synapse Maturation at the Drosophila Neuromuscular Junction

(2016) Mikolaj J. Sulkowski et al.   PLoS Genetics

Angelman Syndrome Protein Ube3a Regulates Synaptic Growth and Endocytosis by Inhibiting BMP Signaling in Drosophila

(2016) Wenhua Li et al.   PLoS Genetics

Drosophila S6 Kinase Like Inhibits Neuromuscular Junction Growth by Downregulating the BMP Receptor Thickveins

(2015) Guoli Zhao et al.   PLoS Genetics

BMP signaling in axon regeneration

(2014) Jian Zhong et al.   CURRENT OPINION IN NEUROBIOLOGY

Postsynaptic glutamate receptors regulate local BMP signaling at the Drosophila neuromuscular junction

(2013) M. Sulkowski et al.   DEVELOPMENT

Brain Tumor Regulates Neuromuscular Synapse Growth and Endocytosis in Drosophila by Suppressing Mad Expression

(2013) W. Shi et al.   JOURNAL OF NEUROSCIENCE

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Spartin Regulates Synaptic Growth and Neuronal Survival by Inhibiting BMP-Mediated Microtubule Stabilization

(2013) Minyeop Nahm et al.   NEURON

Fruit flies as a powerful model to drive or validate pain genomics efforts

(2013) Calvin Leung et al.   PHARMACOGENOMICS

Epsin 1 Promotes Synaptic Growth by Enhancing BMP Signal Levels in Motoneuron Nuclei

(2013) Phillip A. Vanlandingham et al.   PLoS One

PI3K–GSK3 signalling regulates mammalian axon regeneration by inducing the expression of Smad1

(2013) Saijilafu et al.   Nature Communications

The Phr1 Ubiquitin Ligase Promotes Injury-Induced Axon Self-Destruction

(2013) Elisabetta Babetto et al.   Cell Reports

Bimodal Control of Dendritic and Axonal Growth by the Dual Leucine Zipper Kinase Pathway

(2013) Xin Wang et al.   PLOS BIOLOGY

Drosophila cyfip Regulates Synaptic Development and Endocytosis by Suppressing Filamentous Actin Assembly

(2013) Lu Zhao et al.   PLoS Genetics

Optogenetic Analysis of a Nociceptor Neuron and Network Reveals Ion Channels Acting Downstream of Primary Sensors

(2012) Steven J. Husson et al.   CURRENT BIOLOGY

The role of Drosophila Piezo in mechanical nociception

(2012) Sung Eun Kim et al.   NATURE

Optogenetic manipulation of neural circuits and behavior in Drosophila larvae

(2012) Ken Honjo et al.   Nature Protocols

The Ankyrin Repeat Domain of the TRPA Protein Painless Is Important for Thermal Nociception but Not Mechanical Nociception

(2012) Richard Y. Hwang et al.   PLoS One

Thermosensory and Nonthermosensory Isoforms of Drosophila melanogaster TRPA1 Reveal Heat-Sensor Domains of a ThermoTRP Channel

(2012) Lixian Zhong et al.   Cell Reports

The Highwire Ubiquitin Ligase Promotes Axonal Degeneration by Tuning Levels of Nmnat Protein

(2012) Xin Xiong et al.   PLOS BIOLOGY

Construction of a Global Pain Systems Network Highlights Phospholipid Signaling as a Regulator of Heat Nociception

(2012) G. Gregory Neely et al.   PLoS Genetics

Hedgehog Signaling Regulates Nociceptive Sensitization

(2011) Daniel T. Babcock et al.   CURRENT BIOLOGY

The BMP Coreceptor RGMb Promotes While the Endogenous BMP Antagonist Noggin Reduces Neurite Outgrowth and Peripheral Nerve Regeneration by Modulating BMP Signaling

(2011) C. H. E. Ma et al.   JOURNAL OF NEUROSCIENCE

Drosophila Rae1 controls the abundance of the ubiquitin ligase Highwire in post-mitotic neurons

(2011) Xiaolin Tian et al.   NATURE NEUROSCIENCE

TrpA1 Regulates Thermal Nociception in Drosophila

(2011) G. Gregory Neely et al.   PLoS One

Enhancer-driven membrane markers for analysis of nonautonomous mechanisms reveal neuron-glia interactions in Drosophila

(2011) C. Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regeneration of axons in injured spinal cord by activation of bone morphogenetic protein/Smad1 signaling pathway in adult neurons

(2011) P. Parikh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Genome-wide Drosophila Screen for Heat Nociception Identifies α2δ3 as an Evolutionarily Conserved Pain Gene

(2010) G. Gregory Neely et al.   CELL

Bone Morphogenetic Proteins: A critical review

(2010) Beth Bragdon et al.   CELLULAR SIGNALLING

Pickpocket Is a DEG/ENaC Protein Required for Mechanical Nociception in Drosophila Larvae

(2010) Lixian Zhong et al.   CURRENT BIOLOGY

The BMP signaling pathway at the Drosophila neuromuscular junction and its links to neurodegenerative diseases

(2010) Vafa Bayat et al.   CURRENT OPINION IN NEUROBIOLOGY

The Ubiquitin Ligase MYCBP2 Regulates Transient Receptor Potential Vanilloid Receptor 1 (TRPV1) Internalization through Inhibition of p38 MAPK Signaling

(2010) Sabrina Holland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury

(2010) Xin Xiong et al.   JOURNAL OF CELL BIOLOGY

Analysis of Drosophila TRPA1 reveals an ancient origin for human chemical nociception

(2010) Kyeongjin Kang et al.   NATURE

Nociceptor sensitization in pain pathogenesis

(2010) Michael S Gold et al.   NATURE MEDICINE

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

Cytokine Signaling Mediates UV-Induced Nociceptive Sensitization in Drosophila Larvae

(2009) Daniel T. Babcock et al.   CURRENT BIOLOGY

Axotomy-Induced Smad1 Activation Promotes Axonal Growth in Adult Sensory Neurons

(2009) H. Zou et al.   JOURNAL OF NEUROSCIENCE