Exome-wide somatic mutation characterization of small bowel adenocarcinoma

Development of an ErbB4 monoclonal antibody that blocks neuregulin-1-induced ErbB4 activation in cancer cells

(2016) Shogo Okazaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Whole-exome sequencing of duodenal adenocarcinoma identifies recurrent Wnt/β-catenin signaling pathway mutations

(2016) Wei Yuan et al.   CANCER

Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma

(2016) Willy Hugo et al.   CELL

Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS

(2016) Wanglong Qiu et al.   GASTROENTEROLOGY

Chromatin Regulators as a Guide for Cancer Treatment Choice

(2016) Zachary A. Gurard-Levin et al.   MOLECULAR CANCER THERAPEUTICS

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

Classification and characterization of microsatellite instability across 18 cancer types

(2016) Ronald J Hause et al.   NATURE MEDICINE

COSMIC: somatic cancer genetics at high-resolution

(2016) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

BRG1/SMARCA4 is essential for neuroblastoma cell viability through modulation of cell death and survival pathways

(2016) L Jubierre et al.   ONCOGENE

Preclinical efficacy of a RAF inhibitor that evades paradoxical MAPK pathway activation in protein kinaseBRAF-mutant lung cancer

(2016) Ross A. Okimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation

(2016) Marie-Claude Gingras et al.   Cell Reports

BRAFcodons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis

(2015) C. Cremolini et al.   ANNALS OF ONCOLOGY

Clinical detection and categorization of uncommon and concomitant mutations involving BRAF

(2015) Gang Zheng et al.   BMC CANCER

Lifestyle factors and small intestine adenocarcinoma risk: A systematic review and meta-analysis

(2015) Caoimhe M. Bennett et al.   Cancer Epidemiology

Discriminating somatic and germline mutations in tumor DNA samples without matching normals

(2015) Saskia Hiltemann et al.   GENOME RESEARCH

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity

(2015) Matthew T Chang et al.   NATURE BIOTECHNOLOGY

CTCF/cohesin-binding sites are frequently mutated in cancer

(2015) Riku Katainen et al.   NATURE GENETICS

Variation in cancer risk among tissues can be explained by the number of stem cell divisions

(2015) C. Tomasetti et al.   SCIENCE

ERBB Receptors: From Oncogene Discovery to Basic Science to Mechanism-Based Cancer Therapeutics

(2014) Carlos L. Arteaga et al.   CANCER CELL

ERBB2 gene as a potential therapeutic target in small bowel adenocarcinoma

(2014) Anais Laforest et al.   EUROPEAN JOURNAL OF CANCER

Comprehensive molecular characterization of gastric adenocarcinoma

(2014) Adam J. Bass et al.   NATURE

Discovery and saturation analysis of cancer genes across 21 tumour types

(2014) Michael S. Lawrence et al.   NATURE

A general framework for estimating the relative pathogenicity of human genetic variants

(2014) Martin Kircher et al.   NATURE GENETICS

Brg1 Loss Attenuates Aberrant Wnt-Signalling and Prevents Wnt-Dependent Tumourigenesis in the Murine Small Intestine

(2014) Aliaksei Z. Holik et al.   PLoS Genetics

Oncogenic ERBB3 Mutations in Human Cancers

(2013) Bijay S. Jaiswal et al.   CANCER CELL

Small bowel adenocarcinoma: Epidemiology, risk factors, diagnosis and treatment

(2013) Thomas Aparicio et al.   DIGESTIVE AND LIVER DISEASE

Mutational heterogeneity in cancer and the search for new cancer-associated genes

(2013) Michael S. Lawrence et al.   NATURE

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Small bowel adenocarcinomas—existing evidence and evolving paradigms

(2013) Kanwal Raghav et al.   Nature Reviews Clinical Oncology

ATM signalling and cancer

(2013) C A Cremona et al.   ONCOGENE

Deciphering Signatures of Mutational Processes Operative in Human Cancer

(2013) Ludmil B. Alexandrov et al.   Cell Reports

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Activating HER2 Mutations in HER2 Gene Amplification Negative Breast Cancer

(2012) Ron Bose et al.   Cancer Discovery

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

The prevalence of celiac disease in Europe: Results of a centralized, international mass screening project

(2010) Kirsi Mustalahti et al.   ANNALS OF MEDICINE

Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF

(2010) Sonja J. Heidorn et al.   CELL

High-Resolution Array Comparative Genomic Hybridization in Sporadic and Celiac Disease-Related Small Bowel Adenocarcinomas

(2010) B. Diosdado et al.   CLINICAL CANCER RESEARCH

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Small Bowel Cancer in the United States

(2008) Karl Y. Bilimoria et al.   ANNALS OF SURGERY

K-rasMutations and Benefit from Cetuximab in Advanced Colorectal Cancer

(2008) Christos S. Karapetis et al.   NEW ENGLAND JOURNAL OF MEDICINE

Segmentation-based detection of allelic imbalance and loss-of-heterozygosity in cancer cells using whole genome SNP arrays

(2008) Johan Staaf et al.   GENOME BIOLOGY