Activation gating in HCN2 channels

Conformational Flip of Nonactivated HCN2 Channel Subunits Evoked by Cyclic Nucleotides

(2015) Susanne Thon et al.   BIOPHYSICAL JOURNAL

Elementary Functional Properties of Single HCN2 Channels

(2013) S. Thon et al.   BIOPHYSICAL JOURNAL

Unraveling Subunit Cooperativity in Homotetrameric HCN2 Channels

(2012) Klaus Benndorf et al.   BIOPHYSICAL JOURNAL

Free-energy relationships in ion channels activated by voltage and ligand

(2012) Sandipan Chowdhury et al.   JOURNAL OF GENERAL PHYSIOLOGY

Probability Fluxes and Transition Paths in a Markovian Model Describing Complex Subunit Cooperativity in HCN2 Channels

(2012) Klaus Benndorf et al.   PLoS Computational Biology

Tetramerization Dynamics of C-terminal Domain Underlies Isoform-specific cAMP Gating in Hyperpolarization-activated Cyclic Nucleotide-gated Channels

(2011) Marco Lolicato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How subunits cooperate in cAMP-induced activation of homotetrameric HCN2 channels

(2011) Jana Kusch et al.   Nature Chemical Biology

Structural Basis for the cAMP-dependent Gating in the Human HCN4 Channel

(2010) Xinping Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interdependence of Receptor Activation and Ligand Binding in HCN2 Pacemaker Channels

(2010) Jana Kusch et al.   NEURON

Cytoplasmic cAMP-sensing domain of hyperpolarization-activated cation (HCN) channels uses two structurally distinct mechanisms to regulate voltage gating

(2010) N. L. Wicks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hyperpolarization-Activated Cation Channels: From Genes to Function

(2009) Martin Biel et al.   PHYSIOLOGICAL REVIEWS