Dectin-1/2–induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses

The neuroimmune guidance cue netrin-1 controls resolution programs and promotes liver regeneration

(2016) Martin Schlegel et al.   HEPATOLOGY

PGE2 induced in and released by dying cells functions as an inhibitory DAMP

(2016) Sho Hangai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells

(2016) Yinghua Zhao et al.   Nature Communications

Protease activity of Per a 10 potentiates Th2 polarization by increasing IL-23 and OX40L

(2015) Komal Agrawal et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Fasciola hepatica excretory-secretory products induce CD4+T cell anergy via selective up-regulation of PD-L2 expression on macrophages in a Dectin-1 dependent way

(2015) Lorena Guasconi et al.   IMMUNOBIOLOGY

The Schistosoma mansoni T2 ribonuclease omega-1 modulates inflammasome-dependent IL-1β secretion in macrophages

(2015) Brian J. Ferguson et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Opposing Roles of Dectin-1 Expressed on Human Plasmacytoid Dendritic Cells and Myeloid Dendritic Cells in Th2 Polarization

(2015) HyeMee Joo et al.   JOURNAL OF IMMUNOLOGY

Glycomic Analysis of Life Stages of the Human ParasiteSchistosoma mansoniReveals Developmental Expression Profiles of Functional and Antigenic Glycan Motifs

(2015) Cornelis H. Smit et al.   MOLECULAR & CELLULAR PROTEOMICS

Schistosoma mansoni Soluble Egg Antigens Induce Expression of the Negative Regulators SOCS1 and SHP1 in Human Dendritic Cells via Interaction with the Mannose Receptor

(2015) Elsenoor J. Klaver et al.   PLoS One

Dectin-2 Recognition of House Dust Mite Triggers Cysteinyl Leukotriene Generation by Dendritic Cells

(2014) N. A. Barrett et al.   JOURNAL OF IMMUNOLOGY

Helminth-Conditioned Dendritic Cells Prime CD4+T Cells to IL-4 Production In Vivo

(2014) Lisa M. Connor et al.   JOURNAL OF IMMUNOLOGY

Prolonged niacin treatment leads to increased adipose tissue PUFA synthesis and anti-inflammatory lipid and oxylipin plasma profile

(2014) Mattijs M. Heemskerk et al.   JOURNAL OF LIPID RESEARCH

Omega-1 knockdown in Schistosoma mansoni eggs by lentivirus transduction reduces granuloma size in vivo

(2014) Jana Hagen et al.   Nature Communications

C-Type Lectin Receptors Dectin-3 and Dectin-2 Form a Heterodimeric Pattern-Recognition Receptor for Host Defense against Fungal Infection

(2013) Le-Le Zhu et al.   IMMUNITY

Rapamycin and omega-1: mTOR-dependent and -independent Th2 skewing by human dendritic cells

(2013) Leonie Hussaarts et al.   IMMUNOLOGY AND CELL BIOLOGY

Dectin-2 sensing of house dust mite is critical for the initiation of airway inflammation

(2013) D L Clarke et al.   Mucosal Immunology

The Immunobiology of Prostanoid Receptor Signaling in Connecting Innate and Adaptive Immunity

(2013) Hedi Harizi   Biomed Research International

Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators

(2012) J. Dalli et al.   BLOOD

Dectin-1 isoforms contribute to distinct Th1/Th17 cell activation in mucosal candidiasis

(2012) Agostinho Carvalho et al.   Cellular & Molecular Immunology

Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor

(2012) Bart Everts et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Alternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivo

(2012) P. C. Cook et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isoprostane Generation and Function

(2011) Ginger L. Milne et al.   CHEMICAL REVIEWS

Prostaglandin E2 and T cells: friends or foes?

(2011) Vinatha Sreeramkumar et al.   IMMUNOLOGY AND CELL BIOLOGY

Dectin-1 and Dectin-2 in innate immunity against fungi

(2011) S. Saijo et al.   INTERNATIONAL IMMUNOLOGY

Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes

(2011) Nora A. Barrett et al.   JOURNAL OF EXPERIMENTAL MEDICINE

LC/MS/MS method for analysis of E2series prostaglandins and isoprostanes

(2011) Stephen A. Brose et al.   JOURNAL OF LIPID RESEARCH

The Candida Th17 response is dependent on mannan- and  -glucan-induced prostaglandin E2

(2010) S. P. Smeekens et al.   INTERNATIONAL IMMUNOLOGY

Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses

(2010) M. Ritter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Impairment of Human Myeloid Dendritic Cells during Schistosoma haematobium Infection

(2010) Bart Everts et al.   PLoS Neglected Tropical Diseases

Combined TLR2 and TLR4 ligation in the context of bacterial or helminth extracts in human monocyte derived dendritic cells: molecular correlates for Th1/Th2 polarization

(2009) Elly van Riet et al.   BMC IMMUNOLOGY

A comparative proteomic study of the undeveloped and developed Schistosoma mansoni egg and its contents: The miracidium, hatch fluid and secretions

(2009) William Mathieson et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Omega-1, a glycoprotein secreted bySchistosoma mansonieggs, drives Th2 responses

(2009) Bart Everts et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1)

(2009) Svenja Steinfelder et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Prostaglandin E2 enhances T-cell proliferation by inducing the costimulatory molecules OX40L, CD70, and 4-1BBL on dendritic cells

(2008) P. Krause et al.   BLOOD