Chronic restraint stress induces hippocampal memory deficits by impairing insulin signaling

Phosphorylation of p62 by AMP-activated protein kinase mediates autophagic cell death in adult hippocampal neural stem cells

(2017) Shinwon Ha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pro-apoptotic Action of Corticosterone in Hippocampal Organotypic Cultures

(2016) Anna Kurek et al.   NEUROTOXICITY RESEARCH

Control of adult neurogenesis by programmed cell death in the mammalian brain

(2016) Jae Ryun Ryu et al.   Molecular Brain

Valosin-containing protein is a key mediator between autophagic cell death and apoptosis in adult hippocampal neural stem cells following insulin withdrawal

(2016) Bo Kyoung Yeo et al.   Molecular Brain

Flupirtine attenuates chronic restraint stress-induced cognitive deficits and hippocampal apoptosis in male mice

(2015) Pengcheng Huang et al.   BEHAVIOURAL BRAIN RESEARCH

Vascular mineralocorticoid receptor and blood pressure regulation

(2015) Antoine Tarjus et al.   CURRENT OPINION IN PHARMACOLOGY

Hippocampal Insulin Resistance Impairs Spatial Learning and Synaptic Plasticity

(2015) Claudia A. Grillo et al.   DIABETES

A Key Role of Insulin Receptors in Memory: Figure 1

(2015) Fernanda G. De Felice et al.   DIABETES

mTOR: a pharmacologic target for autophagy regulation

(2015) Young Chul Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular mechanisms in the regulation of adult neurogenesis during stress

(2015) Martin Egeland et al.   NATURE REVIEWS NEUROSCIENCE

Hippocampal insulin resistance and cognitive dysfunction

(2015) Geert Jan Biessels et al.   NATURE REVIEWS NEUROSCIENCE

Insulin resistance in brain alters dopamine turnover and causes behavioral disorders

(2015) Andre Kleinridders et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calpain Determines the Propensity of Adult Hippocampal Neural Stem Cells to Autophagic Cell Death Following Insulin Withdrawal

(2015) Kyung Min Chung et al.   STEM CELLS

Regulation of autophagic cell death by glycogen synthase kinase-3β in adult hippocampal neural stem cells following insulin withdrawal

(2015) Shinwon Ha et al.   Molecular Brain

Long-Term Corticosterone Exposure Decreases Insulin Sensitivity and Induces Depressive-Like Behaviour in the C57BL/6NCrl Mouse

(2014) Eva L. van Donkelaar et al.   PLoS One

Interplay between autophagy and programmed cell death in mammalian neural stem cells

(2013) Kyung Min Chung et al.   BMB Reports

Acute psychological stress results in the rapid development of insulin resistance

(2013) Li Li et al.   JOURNAL OF ENDOCRINOLOGY

Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2

(2012) K. D. Copps et al.   DIABETOLOGIA

Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex

(2012) Shuichi Chiba et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Autophagic cell death: Loch Ness monster or endangered species?

(2011) Han-Ming Shen et al.   Autophagy

Cell death by autophagy: facts and apparent artefacts

(2011) D Denton et al.   CELL DEATH AND DIFFERENTIATION

Neuroprotective effects of icariin on corticosterone-induced apoptosis in primary cultured rat hippocampal neurons

(2010) Baojun Liu et al.   BRAIN RESEARCH

HPA axis responsiveness to stress: Implications for healthy aging

(2010) Greti Aguilera   EXPERIMENTAL GERONTOLOGY

Chronic restraint stress impairs neurogenesis and hippocampus-dependent fear memory in mice: possible involvement of a brain-specific transcription factor Npas4

(2010) Jaesuk Yun et al.   JOURNAL OF NEUROCHEMISTRY

Hippocampal memory processes are modulated by insulin and high-fat-induced insulin resistance

(2010) Ewan C. McNay et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Insulin withdrawal-induced cell death in adult hippocampal neural stem cells as a model of autophagic cell death

(2009) Seung-Hoon Baek et al.   Autophagy

Glucocorticoids increase impairments in learning and memory due to elevated amyloid precursor protein expression and neuronal apoptosis in 12-month old mice

(2009) Wei-Zu Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Awake Intranasal Insulin Delivery Modifies Protein Complexes and Alters Memory, Anxiety, and Olfactory Behaviors

(2009) D. R. Marks et al.   JOURNAL OF NEUROSCIENCE

Chronic stress selectively reduces hippocampal volume in rats: a longitudinal magnetic resonance imaging study

(2009) Taekwan Lee et al.   NEUROREPORT

Chronic exogenous corticosterone administration generates an insulin-resistant brain state in rats

(2009) Jelena Osmanovic et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

The Phosphotyrosine Interactome of the Insulin Receptor Family and Its Substrates IRS-1 and IRS-2

(2008) Stefan Hanke et al.   MOLECULAR & CELLULAR PROTEOMICS

Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons

(2008) Alexis M Stranahan et al.   NATURE NEUROSCIENCE

Autophagic Death of Adult Hippocampal Neural Stem Cells Following Insulin Withdrawal

(2008) Seong-Woon Yu et al.   STEM CELLS