Plasma bile acid changes in type 2 diabetes correlated with insulin secretion in two-step hyperglycemic clamp

Role of Bile Acids in Metabolic Control

(2018) Antonio Molinaro et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Diabetes development increased concentrations of the conjugated bile acid, taurocholic acid in serum, while treatment with microencapsulated-taurocholic acid exerted no hypoglycaemic effects

(2017) Sangeetha Mathavan et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Environmental Enteric Dysfunction Is Associated With Altered Bile Acid Metabolism

(2017) Richard D. Semba et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Ghrelin, CCK, GLP-1, and PYY(3–36): Secretory Controls and Physiological Roles in Eating and Glycemia in Health, Obesity, and After RYGB

(2017) Robert E. Steinert et al.   PHYSIOLOGICAL REVIEWS

Analyses of gut microbiota and plasma bile acids enable stratification of patients for antidiabetic treatment

(2017) Yanyun Gu et al.   Nature Communications

Ursodeoxycholic Acid Ameliorated Diabetic Nephropathy by Attenuating Hyperglycemia-Mediated Oxidative Stress

(2016) Aili Cao et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism

(2016) Annika Wahlström et al.   Cell Metabolism

Increased Bile Acid Synthesis and Impaired Bile Acid Transport in Human Obesity

(2016) Rebecca A. Haeusler et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation

(2015) Valentina Tremaroli et al.   Cell Metabolism

Altered Bile Acid Metabolome in Patients with Nonalcoholic Steatohepatitis

(2015) Brian C. Ferslew et al.   DIGESTIVE DISEASES AND SCIENCES

Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity

(2015) Michaela Mueller et al.   JOURNAL OF HEPATOLOGY

Bile diversion to the distal small intestine has comparable metabolic benefits to bariatric surgery

(2015) Charles Robb Flynn et al.   Nature Communications

Postprandial glucose, insulin and incretin responses to different carbohydrate tolerance tests

(2015) Yuying Deng et al.   Journal of Diabetes

The human gut sterolbiome: bile acid-microbiome endocrine aspects and therapeutics

(2015) Jason M. Ridlon et al.   Acta Pharmaceutica Sinica B

Fasting Serum Taurine-Conjugated Bile Acids Are Elevated in Type 2 Diabetes and Do Not Change With Intensification of Insulin

(2014) Marlene Wewalka et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Different effects of two dipeptidyl peptidase-4 inhibitors and glimepiride onβ-cell function in a newly designed two-step hyperglycemic clamp 应用双重高糖钳夹新技术比较两种DPP-IV抑制剂与格列美脲对胰岛β细胞功能的不同影响

(2014) Yifei Zhang et al.   Journal of Diabetes

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

(2013) Sama I. Sayin et al.   Cell Metabolism

Human Insulin Resistance Is Associated With Increased Plasma Levels of 12 -Hydroxylated Bile Acids

(2013) R. A. Haeusler et al.   DIABETES

Activation of transmembrane bile acid receptor TGR5 stimulates insulin secretion in pancreatic β cells

(2012) Divya P. Kumar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Role of Endogenous Incretin Secretion as Amplifier of Glucose-Stimulated Insulin Secretion in Healthy Subjects and Patients With Type 2 Diabetes

(2012) H. J. Woerle et al.   DIABETES

The Effect of a Bile Acid Sequestrant on Glucose Metabolism in Subjects With Type 2 Diabetes

(2012) G. Smushkin et al.   DIABETES

Bile Acids Acutely Stimulate Insulin Secretion of Mouse  -Cells via Farnesoid X Receptor Activation and KATP Channel Inhibition

(2012) M. Dufer et al.   DIABETES

Sex and Age Are Determinants of the Clinical Phenotype of Primary Biliary Cirrhosis and Response to Ursodeoxycholic Acid

(2012) Marco Carbone et al.   GASTROENTEROLOGY

Impaired Generation of 12-Hydroxylated Bile Acids Links Hepatic Insulin Signaling with Dyslipidemia

(2011) Rebecca A. Haeusler et al.   Cell Metabolism

Bile acid signaling after an oral glucose tolerance test

(2011) Silke Matysik et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Insulin-dependent suppression of cholesterol 7α-hydroxlase is a possible link between glucose and cholesterol metabolisms

(2011) Wook-Ha Park et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Ursodeoxycholic acid improves insulin sensitivity and hepatic steatosis by inducing the excretion of hepatic lipids in high-fat diet–fed KK-Ay mice

(2011) Takuma Tsuchida et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The Stunned β Cell: A Brief History

(2010) Ele Ferrannini   Cell Metabolism

Declining  -Cell Function Relative to Insulin Sensitivity With Increasing Fasting Glucose Levels in the Nondiabetic Range in Children

(2010) H. Tfayli et al.   DIABETES CARE

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

(2009) Charles Thomas et al.   Cell Metabolism

Colesevelam lowers glucose and lipid levels in type 2 diabetes: the clinical evidence

(2009) Vivian A. Fonseca et al.   DIABETES OBESITY & METABOLISM

Targeting bile-acid signalling for metabolic diseases

(2008) Charles Thomas et al.   NATURE REVIEWS DRUG DISCOVERY