Article
Environmental Sciences
Md. Aminur Rahman, Md. Abul Hashem, Md. Sohel Rana, Md. Rashidul Islam
Summary: The study revealed that the levels of manganese in tube well water from 9 districts in Bangladesh exceeded the recommended limits by the World Health Organization and Bangladesh Drinking Standard. This widespread contamination poses potential non-carcinogenic health risks to both children and adults, emphasizing the need for authorities to provide manganese-free drinking water.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Environmental Sciences
Mona Dai, Susan Y. Euling, Linda Phillips, Glenn E. Rice
Summary: ExpoKids is a data visualization tool developed to illustrate potential differences in aggregate oral exposure at different childhood lifestages and the adult lifestage. It helps highlight the relative contributions of media and lifestages to chemical exposure.
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
(2021)
Article
Environmental Sciences
Lindsey Garnick, Andrey Massarsky, Adam Mushnick, Claire Hamaji, Paul Scott, Andrew Monnot
Summary: The study evaluated the basis and derivation of state and federal guidelines for PFOA in drinking water, finding significant variations in standards across different regions. The US EPA's Health Advisory for PFOA in drinking water is found to be protective for lactating women.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Engineering, Environmental
Jin-Lei Yang, Albert L. Juhasz, Meng-Ya Li, Jing Ding, Xi-Mei Xue, Dongmei Zhou, Lena Q. Ma, Hong-Bo Li
Summary: This study found that long-term exposure to arsenic, lead, and cadmium in drinking water, at concentrations equivalent to the China provisional guideline values, can lead to a decrease in weight gain in male mice. Additionally, this exposure can cause a reduction in protective bacteria (Akkermansia) and an increase in chronic intestinal inflammation in male mice.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Computer Science, Interdisciplinary Applications
Fuxin Zhang, Hong Zhang, Edoardo Bertone, Rodney Stewart, Xia Shen, Kathy Cinque
Summary: A developed three-dimensional manganese cycle model combined with a hydrodynamic model successfully simulated and predicted the spatial-temporal variation of manganese in a monomictic water reservoir. The study revealed that the thermal structure changes of the reservoir affect the seasonal variation of manganese levels, and the high level of dissolved oxygen in the epilimnion promotes oxidation and settling of manganese. Advection processes driven by wind currents play a vital role in the distribution of soluble manganese near the dam wall.
ENVIRONMENTAL MODELLING & SOFTWARE
(2021)
Review
Environmental Sciences
Yi He, Jingyu Liu, Yanhua Duan, Xiaofei Yuan, Lulu Ma, Ratan Dhar, Yan Zheng
Summary: Approximately 94 to 220 million people worldwide are at risk of drinking well water containing arsenic > 10 pg/L, the WHO guideline value. To identify non-compliant domestic wells, assess health risks and reduce exposure, accurate and rapid on-site inorganic arsenic screening methods are desirable because all domestic wells worldwide need to be tested.
JOURNAL OF ENVIRONMENTAL SCIENCES
(2023)
Article
Environmental Sciences
Paul M. Bradley, Ingrid Y. Padilla, Kristin M. Romanok, Kelly L. Smalling, Michael J. Focazio, Sara E. Breitmeyer, Mary C. Cardon, Justin M. Conley, Nicola Evans, Carrie E. Givens, James L. Gray, L. Earl Gray, Phillip C. Hartig, Christopher P. Higgins, Michelle L. Hladik, Luke R. Iwanowicz, Rachael F. Lane, Keith A. Loftin, R. Blaine McCleskey, Carrie A. McDonough, Elizabeth Medlock-Kakaley, Shannon Meppelink, Christopher P. Weis, Vickie S. Wilson
Summary: A pilot-scale expanded target assessment of mixtures of inorganic and organic contaminants in point-of-consumption drinking water was conducted in Puerto Rico. The study found elevated concentrations of inorganic contaminants, disinfection byproducts, and to a lesser extent per/polyfluoroalkyl substances and phthalates in tap water, supporting further investigation of potential cumulative risks to vulnerable populations in Puerto Rico. The importance of continued broad characterization of drinking-water exposures at the tap with analytical capabilities that better represent the complexity of both inorganic and organic contaminant mixtures known to occur in ambient source waters was emphasized.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Review
Green & Sustainable Science & Technology
Christina Semasinghe, Benny Zuse Rousso
Summary: An elevated concentration of manganese (Mn) in lakes is a common water quality problem. In-lake control mechanisms can be a proactive and efficient strategy to reduce water treatment complexities and costs. However, the feasibility and effectiveness of these mechanisms in different environmental conditions remain unclear. A systematic literature review was conducted to identify and consolidate existing research on in-lake Mn control mechanisms. The review highlighted the benefits and limitations of these mechanisms and provided valuable insights for informed decision-making by water authorities.
Article
Environmental Sciences
Justyna Kubicz, Pawel Lochynski, Adam Pawelczyk, Maciej Karczewski
Summary: This study compared the content of pollutants in groundwater samples taken at 117 measurement points in four regions of Poland during a drought period and in the reference period without drought. It was found that not all locations experience an increase in pollutant concentration during drought, and in some cases drought does not lead to an increase in non-cancerogenic threat. However, changes in groundwater pollution during drought can result in an overall trend of increasing environmental health risk.
Article
Engineering, Environmental
Sean T. McBeath, Adel Hajimalayeri, Saad Y. Jasim, Madjid Mohseni
Summary: This study investigated the use of electrocoagulation technology for the removal of arsenic and manganese from groundwater, achieving successful arsenic removal but limited efficacy for manganese removal. Coupling with oxidative media filtration can further enhance arsenic removal efficiency.
JOURNAL OF WATER PROCESS ENGINEERING
(2021)
Article
Engineering, Environmental
Gopinathan R. Abhijith, Avi Ostfeld
Summary: Recent studies have shown that fluoroalkyl amides can transform into perfluorooctanoic acid during disinfection, serving as an indirect source of contamination to drinking water. Simulation outputs predict a high risk of PFOA exposure, especially among the 1 to 3 years and 4 to 8 years age groups.
Article
Environmental Sciences
Katerina Fialova, Monika Motlochova, Lenka Cermakova, Katerina Novotna, Jana Bacova, Tomas Rousar, Jan Subrt, Martin Pivokonsky
Summary: This study investigated an alternative method of demanganization using a newly synthesized TiO2-based adsorbent. The adsorbent showed high effectiveness in removing Mn2+ due to its unique characteristics. The adsorption process involves electrostatic interactions and ion-exchange. The optimal pH for Mn2+ removal was found to be 7. Different isotherm models were selected based on the presence of different ions.
ENVIRONMENTAL TECHNOLOGY
(2023)
Article
Engineering, Environmental
Guiwei Li, Yuliang Su, Bin Wu, Qi Chen, Jianwei Yu, Min Yang, Baoyou Shi
Summary: The type and dose of disinfectants affect the formation of MnOx deposits in pipes. Chlorination leads to MnOx accumulation, while chloramination has almost no accumulation. Low dose of free chlorine also reduces Mn deposit formation. Biotic Mn(II) oxidation occurs when disinfection is discontinued, and it is inhibited again when disinfection is resumed.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Engineering, Environmental
Ying Yu, Guiwei Li, Ruya Chen, Baoyou Shi
Summary: The transformation and deposition of manganese in drinking water distribution systems can increase the formation risks of disinfection byproducts, primarily due to the accumulation of organic substances in manganese deposits and the inhibitory effect of manganese oxides on the conversion of chlorine and iodine.
Article
Engineering, Environmental
Xin Zhao, Yang Yang, Kun Feng, Xiuheng Wang, Bingfeng Liu, Guojun Xie, Defeng Xing
Summary: The study found that microbial ecological networks in SBFs exhibit resilience to environmental disturbances such as increased influent Mn(II) concentrations, primarily through regulating microbial interactions to maintain stability. However, high manganese loads negatively affect the functional modules for Mn(II) removal.
Article
Medicine, Legal
Honesty Tohon, Mathieu Valcke, Rocio Aranda-Rodriguez, Andy Nong, Sami Haddad
Summary: This study used a reverse dosimetry PBPK modeling approach to estimate toluene atmospheric exposure from urinary measurements of S-benzylmercapturic acid. Results showed that estimating toluene exposure based on spot measurements generated more variability and uncertainty compared to 24-h urine samples. Toluene levels estimated were well below Health Canada's maximum chronic air guidelines, suggesting low health risks.
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2021)
Article
Chemistry, Medicinal
Patrick Poulin, Sami Haddad
Summary: The study aims to guide the prediction of drug hepatic clearance by comparing the accuracy of the free drug hypothesis and ALB-mediated hepatic uptake scaling methods. Results show that the average values from these two scaling methods can predict hepatic clearance with incredible accuracy, validating these boundaries can increase accuracy.
JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Pharmacology & Pharmacy
Pierre Brochu, Jessie Menard, Axelle Marchand, Sami Haddad
Summary: This study evaluated the impact of heat stress on various physiological parameters in male volunteers, finding that most subjects were affected under the higher WBGT condition. Increased respiratory rates, skin blood flow, and decreased renal and liver blood flow were observed.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
(2021)
Article
Toxicology
N. Plattard, N. Venisse, P. Carato, A. Dupuis, Sami Haddad
Summary: During chlorination treatments of drinking water, bisphenol A (BPA) can react with chlorine to form chlorinated derivatives (Cl(x)BPA), which are endocrine disruptors associated with obesity, type II diabetes, and myocardial infarction. This study measured and compared the metabolic kinetics of Cl(x)BPA in the liver of rats and humans. The results showed significant differences in the metabolic constants of Cl(x)BPA between substances and species.
ARCHIVES OF TOXICOLOGY
(2022)
Article
Toxicology
Sandra Nirina Andriamasinoro, Denis Dieme, Caroline Marie-Desvergne, Alessandra Maria Serventi, Maximilien Debia, Sami Haddad, Michele Bouchard
Summary: The study revealed that only a small percentage of the inhaled silver nanoparticles reached the lungs, with most likely remaining in the upper respiratory tract. The nanoparticles that entered the liver and gastrointestinal tract from the lungs suggested a certain ingestion of silver nanoparticles. Additionally, the presence of silver nanoparticles in the blood and extrapulmonary organs indicated a small fraction entering the systemic circulation via direct translocation from the respiratory tract.
ARCHIVES OF TOXICOLOGY
(2022)
Article
Environmental Sciences
Elham Ahmadpour, Stephan Halle, Isabelle Valois, Patrick Eddy Ryan, Sami Haddad, Manuel Rodriguez, Badr El Aroussi, Sabrina Simard, Ianis Delpla, Francois Proulx, Robert Tardif, Maximilien Debia
Summary: This study evaluates the spatial and temporal variations in trichloramine and trichloromethane concentrations within indoor swimming pools. The results show significant variations in concentration over time, suggesting that the common practice of collecting a single 2-hour air sample does not accurately represent the true exposure and health risks for workers. A new 8-hour sampling strategy or a full-shift strategy is recommended for accurate assessment.
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE
(2022)
Article
Environmental Sciences
Pierre Brochu, Jessie Menard, Sami Haddad
Summary: This study determined the parameters of minute ventilation rates, alveolar ventilation rates, cardiac outputs, liver blood flow, and kidneys blood flow in active workers and found that these parameters are interrelated. It also found that the liver blood flow and kidneys blood flow decrease during exertion, which may enhance muscle blood flow. These findings can improve the accuracy of physiologically based toxicokinetic modeling and occupational health assessment.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES
(2022)
Article
Environmental Sciences
Elyse Caron-Beaudoin, Kyle Powys Whyte, Maryse F. Bouchard, Jonathan Chevrier, Sami Haddad, Ray Copes, Katherine L. Frohlich, Dean Dokkie, Sonje Juul, Michele Bouchard, Marc-Andre Verner
Summary: The study found that pregnant women living in Northeastern British Columbia, Canada, where unconventional natural gas exploitation takes place, have higher exposure to VOCs compared to the general Canadian population, and this exposure is associated with well density/proximity.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Sarah Tabbal, Badr El Aroussi, Michele Bouchard, Genevieve Marchand, Sami Haddad
Summary: A method has been developed to quantify 21 mVOCs in urine and human blood using headspace solid phase micro-extraction coupled with gas chromatography-triple quadrupole mass spectrometry. The developed method showed good linearity, low limits of detection, high recoveries, and satisfactory accuracy and precision.
Article
Environmental Sciences
Sarah Tabbal, Badr El Aroussi, Michele Bouchard, Genevieve Marchand, Sami Haddad
Summary: This study developed and validated an analytical method to detect and quantify 21 mVOCs in ambient and exhaled air. The method showed accurate and reliable results with low limits of detection and quantification. The study also revealed variations in mVOCs concentrations between different environments and higher concentrations in exhaled air after exposure in a mold contaminated bedroom. Overall, this method is important for assessing fungal exposure and intervening for the protection of human health.
Article
Toxicology
Sandra Nirina Andriamasinoro, Denis Dieme, Sami Haddad, Michele Bouchard
Summary: This study compared the toxicokinetics of soluble AgNO3 and insoluble Ag NPs and found that exposure to AgNO3 resulted in higher levels of Ag in blood, GI tract, and extrapulmonary tissues but lower levels in lungs.
ARCHIVES OF TOXICOLOGY
(2022)
Article
Medical Laboratory Technology
Noemie Plattard, Riciga Gnanasegaran, Aida Krekesheva, Pascal Carato, Antoine Dupuis, Virginie Migeot, Marion Albouy, Sami Haddad, Nicolas Venisse
Summary: This study developed and validated an analytical method for the quantification of 3,3'-dichlorobisphenol A glucuronide and sulfo-conjugates in plasma samples, and reported for the first time the in vivo occurrence of these metabolites.
THERAPEUTIC DRUG MONITORING
(2023)
Article
Engineering, Chemical
Sandra Nirina Andriamasinoro, Alessandra Maria Serventi, Rene Veillette, Denis Dieme, Sami Haddad, Michele Bouchard
Summary: The toxicity and kinetics of nanoparticles depend on their physical and chemical properties. This study investigated the toxicokinetics of inhaled silver nanoparticles (Ag NPs) and the oxidative stress marker malondialdehyde (MDA). The results showed that the particle number influenced the distribution of Ag NPs in the body and the changes in MDA levels. Rats exposed to Ag NPs with a lower particle number had higher concentrations of Ag in their lungs, blood, and GI tract, but there was no difference in MDA levels between different particle number conditions. Further research is needed to understand the relationship between particle number and biodistribution of Ag NPs.
JOURNAL OF AEROSOL SCIENCE
(2023)
Article
Environmental Sciences
Elham Ahmadpour, Ianis Delpla, Maximilien Debia, Sabrina Simard, Francois Proulx, Jean-Baptiste Serodes, Isabelle Valois, Robert Tardif, Sami Haddad, Manuel Rodriguez
Summary: This study evaluated the levels and variations of Disinfection by-products (DBPs) in indoor swimming pools, focusing on parameters that are easy to measure in order to develop models for predicting levels of DBPs in the air. The results showed that the number of bathers had a significant impact on the levels of DBPs, and CO2 and relative humidity can serve as proxies for monitoring variations in airborne DBPs, highlighting the potential for day-to-day monitoring and optimizing DBPs formation in indoor swimming pools.
ENVIRONMENTAL MONITORING AND ASSESSMENT
(2023)
Article
Engineering, Environmental
Ianis Delpla, Sabrina Simard, Francois Proulx, Jean-Baptiste Serodes, Isabelle Valois, Elham Ahmadpour, Maximilien Debia, Robert Tardif, Sami Haddad, Manuel Rodriguez
Summary: The study monitored the water quality of two indoor swimming pools and found that swimmers' attendance had a significant impact on the levels of DBPs in the pools, particularly when there were more swimmers present. The levels of THMs and HAAs reached their peak during periods of high swimmer attendance.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)