Article
Virology
Laura Cristina Machado Ribeiro de Souza, Carla Trevisan Martins Ribeiro, Tatiana Hamanaka, Luciana Castaneda Ribeiro, Nathalia Crsitina Oliveira de Souza, Sheila Moura Pone, Karin Nielsen-Saines, Elizabeth B. Brickley, Maria Elisabeth Lopes Moreira, Marcos Vinicius da Silva Pone
Summary: Understanding functioning and disabilities in children with Congenital Zika Syndrome (CZS) is crucial for health planning. In this study, disabilities in children with CZS were characterized based on the biopsychosocial model of the International Classification of Functioning, Disability and Health (ICF). The findings showed high rates of severe impairment and microcephaly in these children, as well as cognitive impairment, muscle tone problems, and speech deficits. Movement limitations were prevalent, particularly in postural transfers and displacements. Environmental factors such as product use and access to health services were identified. These findings highlight the importance of using the ICF model in assessing health domains.
Article
Virology
Rosa Estela Gazeta, Ana Paula Antunes Pascalicchio Bertozzi, Rita de Cassia de Aguirre Bernardes Dezena, Andrea Cristina Botelho Silva, Thamirys Cosmo Gillo Fajardo, Daniel T. Catalan, Maria de Fatima Valente Rizzo, Antonio Fernandes Moron, Antoni Soriano-Arandes, Nuria Sanchez Clemente, Tania Quintella, Dora Fix Ventura, Francisco Max Damico, Valtenice de Cassia Rodrigues de Matos Franca, Juliana Paula Gomes de Almeida, Ana Laura de Sene Amancio Zara, Lucas Castro Pires, Cohort Zika virus Jundiai, Saulo Duarte Passos
Summary: Congenital Zika virus infection can result in a wide range of clinical manifestations, including developmental delays and neurological abnormalities. Longitudinal study of high-risk pregnant women and their newborns showed that some patients may continue to experience developmental delays beyond the age of three, highlighting the importance of long-term follow-up.
Review
Dentistry, Oral Surgery & Medicine
Adriano Referino da Silva Sobrinho, Leticia Francine Silva Ramos, Ytalo Lourenco Maciel, Herika de Arruda Mauricio, Renata de Oliveira Cartaxo, Stefania Jeronimo Ferreira, Pedro Henrique Sette-de-Souza
Summary: The study analyzed the common orofacial disorders in children with microcephaly associated with ZIKV infection based on 11 studies conducted in the Brazilian Northeast region between 2018 and 2020. The main findings included delays in tooth eruption and deformation in oral structures.
Article
Virology
Eder M. S. Fialho, Emanoel M. Veras, Caroline M. de Jesus, Lillian N. Gomes, Ricardo Khouri, Patricia S. Sousa, Marizelia R. C. Ribeiro, Rosangela F. L. Batista, Luciana C. Costa, Flavia R. F. Nascimento, Antonio A. M. Silva, Paulo V. Soeiro-Pereira
Summary: This study investigated the immune profiles of children with Congenital Zika Syndrome (CZS) and their mothers who were infected with the Zika virus during pregnancy. The results showed that both children and mothers had an inflammatory immune profile characterized by increased interleukin-17 levels and a reduction in CD4+ T lymphocyte subpopulation. Additionally, the maternal group also exhibited a reduction in B lymphocyte population.
Article
Multidisciplinary Sciences
Lilian F. Muniz, Rebeka J. F. Maciel, Danielle S. Ramos, Katia M. G. Albuquerque, Angela C. Leao, Vanessa Van der Linden, Enny S. Paixao, Elizabeth B. Brickley, Marli T. Cordeiro, Gabriella G. S. Leitao, Silvio S. Caldas, Mariana C. Leal
Summary: This study assessed the auditory function of children with congenital Zika syndrome during their first three years of life. Screening and diagnostic tests revealed that 9.3% of the children experienced sensorineural hearing loss, but there were no cases of delayed-onset or progressive deficits.
Article
Multidisciplinary Sciences
Jeronimo Faustino Rego Filho, Claudia Sena, Rubens Wajnsztejn
Summary: This study aimed to analyze the burden on caregivers of children with congenital Zika syndrome in Brazil using the Zarit Burden interview scale. The results showed that contracting the Zika virus in the first trimester of pregnancy, lack of paid work, financial scarcity, full-time dedication to the child, and lack of time for themselves increase the burden on caregivers.
Article
Infectious Diseases
Tamires Barradas Cavalcante, Marizelia Rodrigues Costa Ribeiro, Patricia da Silva Sousa, Elaine de Paula Fiod Costa, Maria Teresa Seabra Soares de Brito e Alves, Vanda Maria Ferreira Simoes, Rosangela Fernandes Lucena Batista, Eliana Harumi Morioka Takahasi, Glaucio Andrade Amaral, Ricardo Khouri, Maria dos Remedios Freitas Carvalho Branco, Ana Karolina Torres Mendes, Luciana Cavalcante Costa, Marcos Adriano Garcia Campos, Antonio Augusto Moura da Silva
Summary: The study compared the growth and development outcomes of children with CZS born with and without microcephaly up to their third birthday. Children born without microcephaly showed faster head circumference growth in early stages, and were less likely to have brain damage, ophthalmic abnormalities, and drug-resistant epilepsy. However, differences between the two groups tended to diminish with age.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Virology
Eder M. S. Fialho, Emanoel M. Veras, Caroline M. de Jesus, Ricardo Khouri, Patricia S. Sousa, Marizelia R. C. Ribeiro, Luciana C. Costa, Lillian N. Gomes, Flavia R. F. Nascimento, Antonio A. M. Silva, Paulo V. Soeiro-Pereira
Summary: This study aims to assess the immuno-inflammatory profile of mothers and their children diagnosed with CZS. The results showed a correlation between the leukocyte profile of CZS+ children and their mothers, especially in monocytes. CZS+ children demonstrated normal HLA expression and higher hydrogen peroxide concentration.
Article
Medicine, General & Internal
Eric Osoro, Irene Inwani, Cyrus Mugo, Elizabeth Hunsperger, Jennifer R. Verani, Victor Omballa, Dalton Wamalwa, Chulwoo Rhee, Ruth Nduati, John Kinuthia, Hafsa Jin, Lydia Okutoyi, Dufton Mwaengo, Brian Maugo, Nancy A. Otieno, Harriet Mirieri, Mufida Shabibi, Peninah Munyua, M. Kariuki Njenga, Marc-Alain Widdowson
Summary: The incidence of Zika virus infection was high in a pregnancy cohort in coastal Kenya, but there was little evidence of Zika virus transmission. The prevalence of severe microcephaly among newborns was higher compared to estimates from facility-based studies in Europe and Latin America.
Article
Biochemistry & Molecular Biology
Andrew Kodani, Kristeene A. Knopp, Elizabeth Di Lullo, Hanna Retallack, Arnold R. Kriegstein, Joseph L. DeRisi, Jeremy F. Reiter
Summary: ZIKV infection disrupts centrosome organization and affects the localization and stability of centrosomal proteins, as well as the function of regulators of the innate immune response, thereby tempering the immune response.
Article
Virology
Lais Cristine Delgado da Hora, Lilian Ferreira Muniz, Leonardo Gleygson Angelo Venancio, Karina Paes Advincula, Jessica Dayane da Silva, Diana Babini Lapa de Albuquerque Britto, Democrito de Barros Miranda Filho, Elizabeth B. Brickley, Ricardo Arraes de Alencar Ximenes, Silvio da Silva Caldas Neto, Mariana de Carvalho Leal
Summary: Prenatal exposure to ZIKV can have negative effects on auditory pathways, but CAEP testing can reveal preserved neural function. MRI results show structural changes in the brains of microcephalic children, but CAEP results indicate that these children still have some ability to process sound stimuli.
Letter
Immunology
Claudine A. Kombila Koumavor, Eric Elguero, Eric M. Leroy
Summary: The study suggests a possible association between a 2007 outbreak of febrile illness and an increase in microcephaly as well as potentially ZIKV infection in Gabon.
EMERGING INFECTIOUS DISEASES
(2021)
Article
Medicine, General & Internal
Silvina Noemi Contreras-Capetillo, Jose Rafael Palma-Baquedano, Nina Valadez-Gonzalez, Pablo Manrique-Saide, Hirian Alonso Moshe Barrera-Perez, Doris Pinto-Escalante, Norma Pavia-Ruz
Summary: The article reports a Zika positive patient with a sequence of fetal brain disruption, arthrogryposis, and absence of the distal third of the right forearm. This case expands clinical observations of congenital Zika syndrome and may be related to disruptive vascular events.
FRONTIERS IN MEDICINE
(2021)
Article
Clinical Neurology
Tamires Barradas Cavalcante, Marizelia Rodrigues Costa Ribeiro, Patricia da Silva Sousa, Elaine de Paula Fiod Costa, Maria Teresa Seabra Soares de Britto, Vanda Maria Ferreira Simoes, Rosangela Fernandes Lucena Batista, Eliana Harumi Morioka Takahasi, Glaucio Andrade Amaral, Ricardo Khouri, Maria dos Remedios Freitas Carvalho Branco, Ana Karolina Torres Mendes, Luciana Cavalcante Costa, Marcos Adriano Garcia Campos, Antonio Augusto Moura da Silva
Summary: This study examined characteristics associated with drug resistant epilepsy in children up to 36 months old with Congenital Zika Syndrome (CZS) and found that 65% of the children had drug resistant seizures, which were linked to the severity of neurological damage.
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
(2022)
Article
Pediatrics
Natalia Romani, Maria Pieras, Marie Antoinette Frick, Elena Sulleiro, Carlota Rodo, Aroa Silgado, Anna Suy, Maria Espiau, Claire Thorne, Carlo Giaquinto, Ana Felipe-Rucian, Pere Soler-Palacin, Antoni Soriano-Arandes
Summary: This study aimed to describe the early neurodevelopmental outcomes of children prenatally exposed to Zika virus (ZIKV) in a non-endemic area. The study found that although there were some adverse outcomes related to ZIKV in children at birth, the prevalence of exposure was low in asymptomatic newborns. Therefore, the study suggests that primary care pediatricians should closely monitor these children.
Article
Biochemistry & Molecular Biology
Pedro Simao Sousa Mendonca, Jeziel Rodrigues dos Santos, Osmair Vital de Oliveira, Jose Divino dos Santos, Elson Longo
Summary: Computational chemistry methods were used to study the potential of a silicon nanotube as a virucidal agent against COVID-19. The results showed that the nanotube had high reactivity and favorable binding energy with the receptor-binding domain of the SARS-CoV-2 spike protein.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Chemistry, Multidisciplinary
Thaiane Robeldo, Lucas S. Ribeiro, Lida Manrique, Andressa Mayumi Kubo, Elson Longo, Emerson Rodrigues Camargo, Ricardo Carneiro Borra
Summary: Low oxygen concentration in the tumor microenvironment is a major obstacle for photodynamic therapy of malignant tumors. Titanium dioxide (Ti(OH)(4)) shows potential as a photosensitizer for bladder cancer treatment due to its ability to produce high levels of reactive oxygen species (ROS) regardless of oxygen concentrations. In this study, exposure of Ti(OH)(4) to visible light stimulated ROS production and dose-dependently induced necrosis in tumor cells. Ti(OH)(4) also inhibited cell proliferation and migration in low concentrations. Mechanistically, Ti(OH)(4) may initiate type II cell death through autophagic dysfunction mechanisms associated with high ROS production.
Review
Medicine, General & Internal
Adriele de Morais Nunes, Ana Tereza do Nascimento Sales Figu Fernandes, Adynna Tevina de Castro Silva, Mayara Fabiana Pereira Costa, Karolinne Souza Monteiro, Silvana Alves Pereira
Summary: This systematic review aims to evaluate the effects of conventional and non-conventional respiratory physiotherapies on pulmonary mechanics of newborns. Randomized clinical trials reporting thoracoabdominal synchrony, lung volumes and capacities, respiratory discomfort and pain will be included in the study. The results will be disseminated through academic journals, conferences, and social media.
Article
Nanoscience & Nanotechnology
Marisa Carvalho de Oliveira, Marcelo Assis, Luiz Gustavo Pagotto Simoes, Daniel Tamassia Minozzi, Renan A. . P. Ribeiro, Juan Andres, Elson Longo
Summary: This research reveals the biocidal activity of SiO2-Ag composites, which can eliminate Staphylococcus aureus and SARS-CoV-2 virus in just 2 minutes. The material destroys the virus structure by generating reactive oxygen species, as predicted by first-principles calculations.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Engineering, Electrical & Electronic
Joao Paulo de Campos da Costa, Leonelio Cichetto Junior, Estacio Paiva de Araujo, Adryelle do Nascimento Arantes, Elson Longo, Adenilson Jose Chiquito, Joao Paulo Carmo
Summary: This article presents the development of a VOC gas sensor based on a PCB multiplexed IDE sensor, highlighting the use of graphite as a sensing material and describing the design and manufacturing of the sensors. Acetone exhibited the highest detection sensitivity, and the sensors maintained stability and repeatability after six months of evaluation.
IEEE SENSORS JOURNAL
(2022)
Article
Environmental Sciences
Gracimary A. Teixeira, Norrara S. O. Holanda, Ingrid G. Azevedo, Julia R. Moura, Jovanka B. L. de Carvalho, Silvana A. Pereira
Summary: The aim of this study was to assess the factors associated with the number of prenatal visits among women delivering in a public maternity hospital in northeastern Brazil. The study found that women with less than four prenatal visits were more likely to give birth to low birth weight and preterm infants compared to those with more than four prenatal visits.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Chemistry, Physical
Laura O. Libero, Lara K. Ribeiro, Luis I. Granone, Maria S. Churio, Josiane C. Souza, Valmor R. Mastelaro, Juan Andres, Elson Longo, Lucia H. Mascaro, Marcelo Assis
Summary: This study reports on the immobilization of Fe-2(MoO4)(3) in chitosan films and its effect on the oxidation reaction of sulfide derivatives. The catalyst showed good yields and excellent selectivity, even tolerating oxidatively sensitive functional groups. The key success of the selective oxidation was attributed to the presence of hydroxyl radical, center dot OH, and the Fe3+/Fe2+ Fenton-like process. Additionally, the synergistic effect between Fe-2(MoO4)(3) and chitosan was demonstrated in the selective oxidation of sulfides to sulfones. This work provides a design strategy for efficient catalysts that can be applied to other semiconductors and oxidation processes.
Article
Nanoscience & Nanotechnology
Krishtappa Manjunatha, Hsin-Hao Chiu, Ming-Kang Ho, Tsu-En Hsu, Shih-Lung Yu, Chu-En Chin, Chia-Liang Cheng, Marisa Carvalho de Oliveira, Elson Longo, Renan A. P. Ribeiro, Hanumanthappa Nagabhushana, Sheng Yun Wu
Summary: By using the co-precipitate method, Mg-doped CoCr2O4 nanoparticles with controlled particle size were synthesized and their properties were investigated. The magnetic inhomogeneity of the nanoparticles was identified as the cause of the observed exchange bias effect. The nanoparticles showed potential applications in magnetic memory and magnetocaloric effect fields.
ACS APPLIED NANO MATERIALS
(2023)
Article
Obstetrics & Gynecology
Pedro Ykaro Fialho Silva, Maria Clara Lima da Cruz, Ingrid Guerra Azevedo, Rafaela Silva Moreira, Klayton Galante Sousa, Silvana Alves Pereira
Summary: This study found that infants born from mothers with COVID-19 were at a higher risk of motor developmental delay and socioemotional alterations compared to infants born from mothers not exposed to COVID-19. Furthermore, mothers in COVID-19 families may be at risk for depression, substance abuse, food insecurity, and domestic violence.
INTERNATIONAL JOURNAL OF WOMENS HEALTH
(2023)
Article
Physics, Multidisciplinary
Jesus H. Warnes, Fagner M. de Paula, Natanael C. Costa, Olimpio P. de Sa Neto
Summary: In this research, the quantum coherence theory has been applied to the Jaynes-Cummings model for three types of quenched disorder distribution: uniform, Gaussian, and Cauchy-Lorentz. Under certain conditions, a beat-damping behavior on the dynamics of the 11-norm of coherence has been observed. This phenomenon is more evident for the uniform disorder distribution.
Article
Chemistry, Inorganic & Nuclear
D. C. Amaral, L. S. R. Rocha, L. I. Granone, M. M. Lage, M. S. Churio, M. D. Sanchez, E. Longo, H. M. S. Nascimento, M. Assis, F. Moura, M. A. Ponce
Summary: The influence of manganese modification on the spectroscopic features of manganese-doped CeO2 systems synthesized by the microwave-assisted hydrothermal route and their correlation with the presence of O defective structures were verified. Raman and electron paramagnetic resonance studies confirmed the presence of defective clusters formed by dipoles and/or quadrupoles. The number of paramagnetic species was found to be inversely proportional to the doping concentration, resulting in an increase in the Mn2+ signal, likely due to the reduction of Mn3+ species after the interaction with CO. X-ray photoelectron spectroscopy data showed significant changes in the Ce3+ and Mn2+ configurations with the introduction of manganese modification, suggesting the formation of nonparamagnetic Ce4+ species and the persistence of paramagnetic Mn2+ species.
INORGANIC CHEMISTRY
(2023)
Article
Public, Environmental & Occupational Health
Bruno Henrique Silva de Souza, Sabrinne Suelen Santos Sampaio, Julia Raffin Moura, Hesli Holanda, Vanessa Braga Torres, Ingrid Guerra Azevedo, Ingrid Fonseca Damasceno Bezerra, Silvana Alves Pereira
Summary: This study evaluated the effects of manual hyperinflation maneuver (MHM) and thoracoabdominal rebalancing method (TRM) on bronchial hygiene in preterm newborns. The results showed that both techniques removed a similar amount of secretion and did not negatively affect the response of the autonomous, motor, and regulatory systems.
HEALTH SCIENCE REPORTS
(2023)
Article
Materials Science, Multidisciplinary
Guilhermina Ferreira Teixeira, Heitor Secco Seleghini, Wagner Benicio Bastos, Natalia Jacomaci, Bojan Stojadinovic, Zorana Dohcevic-Mitrovic, Flavio Colmati, Miguel Angel San-Miguel, Elson Longo, Maria Aparecida Zaghete
Summary: Na2Nb2O6•H2O fibers were synthesized using a microwave-assisted hydrothermal method and used as a precursor for obtaining NaNbO3 fibers with piezoelectric characteristics. The NaNbO3 fibers consist of a mix of antiferroelectric and ferroelectric orthorhombic phases. Piezoresponse force microscopy revealed that the fibers have regions with ferroelectric domains and regions with no ferroelectric characteristics.
JOURNAL OF MATERIALS CHEMISTRY C
(2023)
Article
Pediatrics
Norrara Scarlytt de Oliveira Holanda, Maria Clara Lima da Cruz, Cynthia Cibelle dos Santos Xavier, Valeria Azevedo de Almeida, Cristiane Aparecida Moran, Ingrid Guerra Azevedo, Adriele de Morais Nunes, Silvana Alves Pereira
Summary: The objective of this study is to track the blood pressure trajectory of healthy infants in Northeast Brazil during the first year of life. The results showed that systolic and diastolic blood pressure increased with age, and the increase in blood pressure was not influenced by gender or type of delivery.
GLOBAL PEDIATRIC HEALTH
(2023)
Article
Chemistry, Inorganic & Nuclear
L. X. Lovisa, T. B. O. Nunes, R. R. Y. O. V. Wilson, E. Longo, M. Daldind, M. R. D. Bomio, F. V. Motta
Summary: This study successfully synthesized zinc-doped Bi2WO6 and demonstrated its good degradation performance for methylene blue through photocatalytic tests. Doping with Zn2+ improved photoluminescence, but excessive Zn2+ concentration inhibited photocatalytic properties.
DALTON TRANSACTIONS
(2022)
