Review
Nutrition & Dietetics
Ionela-Daniela Morariu, Liliana Avasilcai, Madalina Vieriu, Vasile Valeriu Lupu, Branco-Adrian Morariu, Ancuta Lupu, Paula-Cristina Morariu, Oana-Lelia Pop, Iuliana Magalena Starcea, Laura Trandafir
Summary: Irritable bowel syndrome is a common gastrointestinal disease that causes various symptoms such as bloating, abdominal pain, and diarrhea. A low-FODMAP diet has been shown to effectively reduce these symptoms and improve the quality of life for patients with irritable bowel syndrome.
Article
Nutrition & Dietetics
Charlotte Debras, Eloi Chazelas, Bernard Srour, Chantal Julia, Elodie Schneider, Emmanuelle Kesse-Guyot, Cedric Agaesse, Nathalie Druesne-Pecollo, Valentina A. Andreeva, Gaelle Wendeu-Foyet, Pilar Galan, Serge Hercberg, Melanie Deschasaux-Tanguy, Mathilde Touvier
Summary: The study conducted on a large cohort of French adults from the NutriNet-Sante cohort showed a significant association between FODMAP intake and the risk of cancer development. In particular, oligosaccharides were significantly associated with colorectal cancer risk. Further research is needed to confirm these findings and explore potential underlying mechanisms.
JOURNAL OF NUTRITION
(2022)
Review
Pharmacology & Pharmacy
Chao-Rong Xie, Bin Tang, Yun-Zhou Shi, Wen-Yan Peng, Kun Ye, Qing-Feng Tao, Shu-Guang Yu, Hui Zheng, Min Chen
Summary: This study evaluated the most effective approaches for managing irritable bowel syndrome (IBS) by analyzing different combinations and components of probiotics or a low FODMAP diet. The results showed that Lactobacillus was the most effective component for relieving IBS symptoms, while Bifidobacterium and Bacillus were potentially effective and require further verification.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Nutrition & Dietetics
Elise Nordin, Carl Brunius, Rikard Landberg, Per M. Hellstrom
Summary: This study found that a diet rich in FODMAPs had a modest effect on IBS symptoms, while gluten had no effect on IBS symptoms. The study also revealed significant individual differences in response to different interventions.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Joost P. Algera, Dagsu Demir, Hans Tornblom, Sanna Nybacka, Magnus Simren, Stine Storsrud
Summary: This study compared the effects of diets with low vs. moderate FODMAP content on gastrointestinal symptoms and bowel habits in patients with irritable bowel syndrome (IBS). The results showed that a low FODMAP diet reduced overall GI symptom severity and improved stool consistency and frequency. Additionally, the severity of IBS at baseline could predict the clinical response to a low FODMAP diet.
CLINICAL NUTRITION
(2022)
Review
Endocrinology & Metabolism
Eamonn M. M. Quigley
Summary: The review assesses the role of a group of poorly absorbed carbohydrates (FODMAPs) in gastrointestinal pathophysiology. Although evidence for the efficacy of low FODMAP diets in IBS is accumulating, recent studies show a decline in the magnitude of this effect. Comparisons to other dietary approaches have yielded conflicting results, with some studies suggesting superiority and others finding parity. Concerns about long-term nutritional, psychological, and microbial impacts of FODMAP restriction have been raised, but they do not appear to be clinically significant as long as the diet is administered as recommended. The mechanisms by which FODMAPs cause gastrointestinal symptoms are still being explored.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
(2022)
Review
Gastroenterology & Hepatology
William D. Chey, Laurie Keefer, Kevin Whelan, Peter R. Gibson
Summary: Irritable bowel syndrome (IBS) is a common condition that affects quality of life and costs healthcare systems billions of dollars annually. In addition to medication, behavioral techniques and dietary modifications are effective in treating IBS.
Review
Nutrition & Dietetics
Jongsung Hahn, Jeongwon Choi, Min Jung Chang
Summary: This meta-analysis revealed that a low fermentable oligo-, di-, monosaccharides, and polyols diet (LFD) has a moderate reduction effect on the symptom severity and a slight improvement effect on the quality of life of irritable bowel syndrome (IBS) patients, as well as a significant improvement in stool habits.
Review
Microbiology
Tarek Mazzawi
Summary: Research suggests that manipulating gut microbiota can improve symptoms of irritable bowel syndrome (IBS), with dietary management and other approaches showing promise in changing gut composition and alleviating IBS symptoms. However, more research is needed to identify the exact mixture of beneficial bacteria.
Article
Gastroenterology & Hepatology
Prashant Singh, Caroline Tuck, Peter R. Gibson, William D. Chey
Summary: Irritable bowel syndrome (IBS) and functional constipation (FC) are common disorders that affect millions of people globally. This article discusses the importance of dietary interventions, including general dietary advice and a low FODMAP diet, in the management of these conditions. It also summarizes the possible mechanisms of FODMAP-mediated IBS, the approach of implementing a low FODMAP diet, and the efficacy of fiber and other dietary interventions in treating IBS and FC.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2022)
Review
Pharmacology & Pharmacy
Michael Camilleri, Saam Dilmaghani
Summary: This narrative review provides an update on current approaches for the treatment of pain, global symptoms, or relief in irritable bowel syndrome (IBS). The review evaluates medications, dietary interventions, fecal microbial transplantation (FMT), electrical approaches, and behavioral therapies. The evidence suggests only modest benefit in global IBS symptoms and pain relief. A future approach involving validated biomarkers could individualize treatment and improve outcomes.
PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Pediatrics
Yasmine Gamal Abdou El Gendy, Mohammad Ashraf Abdel Wahed, Mostafa Hussein Hassan Ragab, Yosra Mohamed Mohsen Awad
Summary: A clinical trial on 50 children aged 3-18 with FAP showed that a low FODMAP diet significantly improved pain intensity and quality of life, with patients also gaining weight.
PEDIATRIC GASTROENTEROLOGY HEPATOLOGY & NUTRITION
(2022)
Article
Endocrinology & Metabolism
Katarzyna Miroslawa Boradyn, Katarzyna Eufemia Przybylowicz, Elzbieta Jarocka-Cyrta
Summary: The pilot study suggests that the low FODMAP diet is not effective in reducing symptoms in children with FAP. The NICE diet group experienced significant improvement in abdominal pain and stool consistency. No statistical significance was found in the improvement of abdominal symptoms in the low FODMAP group.
ANNALS OF NUTRITION AND METABOLISM
(2021)
Article
Food Science & Technology
Tanisa Patcharatrakul, Sittikorn Linlawan, Suppawatsa Plaidum, Sutep Gonlachanvit
Summary: A randomized crossover study found that wheat noodles induced more GERD symptoms than rice noodles in patients with overlapping GERD-IBS, which may be associated with increased intestinal gas production. A low FODMAPs diet may help relieve postprandial GERD symptoms in these patients.
Article
Nutrition & Dietetics
Yawen Zhang, Lijun Feng, Xin Wang, Mark Fox, Liang Luo, Lijun Du, Binrui Chen, Xiaoli Chen, Huiqin He, Shuwen Zhu, Zhefang Hu, Shujie Chen, Yanqin Long, Yubin Zhu, Li Xu, Yanyong Deng, Benjamin Misselwitz, Brian M. Lang, Bahtiyar Yilmaz, John J. Kim, Chung Owyang, Ning Dai
Summary: Both LFD and TDA were effective in reducing symptoms in Chinese IBS-D patients, but LFD led to earlier improvements in stool frequency and excessive wind. The therapeutic effect of LFD was associated with changes in fecal microbiota and fermentation index.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)