Article
Psychology, Clinical
Yanbin Niu, Zixuan Li, Jeremy W. Pettit, George A. Buzzell, Jingjing Zhao
Summary: This study found that social anxiety symptoms are most likely to occur during adolescence, and the error-related negativity (ERN) may serve as a neural marker for social anxiety, especially for errors committed in front of peers. Fear of negative evaluation (FNE) specifically predicts ERN in the presence of peers. These findings have important implications for research and theory on adolescent social anxiety.
PSYCHOLOGICAL MEDICINE
(2023)
Editorial Material
Neurosciences
Peter E. Clayson, Emily S. Kappenman, William J. Gehring, Gregory A. Miller, Michael J. Larson
Summary: The large data set for ERN and Pe components of scalp-recorded ERP is not yet ready for use in research and especially clinical applications due to incomplete understanding of amplitude differences, lack of method standardization, and use of convenience samples. More research is encouraged to understand ERN score differences and factors influencing variation, as well as dissemination of protocols for data collection and processing to move towards standardization and useful norms in ERP studies.
Review
Psychology, Biological
Rune Boen, Daniel S. Quintana, Cecile D. Ladouceur, Christian K. Tamnes
Summary: This study investigated the age and age moderation effects on error-related negativity (ERN) and error positivity (Pe) during development. The results showed that age was negatively associated with ERN, but not significantly associated with Pe, except for in a group comparison between younger and older adolescents. Task type and electrode site were found to moderate the age effects on ERN and Pe.
Article
Psychology, Biological
Franziska Martin, Martin Holtmann, Tanja Legenbauer
Summary: The present study examines the relationship between shame proneness and performance monitoring in adolescents, specifically looking at the influence of shame proneness on the correlation between depressive symptoms and error-related negativity (ERN) or error positivity (Pe) amplitudes. The study found that shame proneness and ERN amplitudes were correlated, suggesting the importance of further research on the relationship between shame proneness and punishment sensitivity.
INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY
(2022)
Article
Behavioral Sciences
Ines Macedo, Rita Pasion, Fernando Barbosa, Fernando Ferreira-Santos
Summary: The study found that anxiety emerged as the main explanation for altered patterns of error monitoring in a transdiagnostic sample. Anxiety predicted increased ERN amplitudes, while perfectionism did not show significant results. Exploratory analyses revealed that anxiety and physiological depression led to a reduction in the Error Positivity component (Pe).
BEHAVIOURAL BRAIN RESEARCH
(2021)
Article
Psychology, Biological
C. Dell'Acqua, G. Hajcak, N. Amir, N. J. Santopetro, C. J. Brush, A. Meyer
Summary: This study aimed to examine error monitoring in early adolescents with depression. Analysing EEG data in both time and time-frequency domains, it revealed reduced ERN amplitude, reduced error-related theta power, and increased error-related beta power in the depression group compared to the control group. Furthermore, both theta and beta power were independently related to an increased likelihood of being diagnosed with depression, while the ERN was not.
INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY
(2023)
Article
Psychology, Biological
Elizabeth A. Bauer, Annmarie MacNamara
Summary: Mistakes can lead to aversive outcomes. Error monitoring may be maladaptive for individuals who lack control over aversive outcomes. This study found that participants without agency over punishment showed smaller error-related negativity (ERN) and higher error rates. Additionally, punishment only reduced error rates for participants with agency.
Article
Psychology, Biological
I. Korolczuk, B. Burle, J. T. Coull, H. Oginska, M. Ociepka, M. Senderecka, K. Smigasiewicz
Summary: This study aimed to investigate whether error monitoring increases in unpredictable contexts, and whether ERN is also increased. The results showed that ERN increased when participants evaluated their responses in unpredictable moments. Furthermore, EMG data revealed slower response times and fewer inhibitory errors in temporally unpredictable trials, indicating enhanced control of unwanted actions. Overall, this study demonstrated that temporal unpredictability increases the control of unwanted actions.
Article
Clinical Neurology
Xu Ding, Huihua Fang, Yutong Liu, Lin Zheng, Xiangru Zhu, Hongxia Duan, Jianhui Wu
Summary: This study aimed to explore the relationship between trait resilience and bottom-up automatic information processing in healthy adults. The results showed that higher resilience was associated with slower automatic detection speed and lower sensory sensitivity.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Psychology, Clinical
Alexandria Meyer, Lyndsey Chong, Karl Wissemann, Lushna Mehra, Isaac Mirzadegan
Summary: This study uses an experimental medicine approach to examine how a single-session, computerized intervention affects a transdiagnostic neural marker of risk (ERN) in children. The ERN has been associated with various anxiety disorders, obsessive-compulsive disorder, and depressive disorders. The study finds that the treatment condition predicts changes in self-reported error sensitivity but not changes in ERN.
Editorial Material
Neurosciences
Annmarie MacNamara, Michael J. Imburgio, Kaylin E. Hill, Iulia Banica, Anna Weinberg, Dan Foti
Summary: Clayson and colleagues raised concerns about our norms for ERN, suggesting that it should not be normed due to unknown factors. We argue that the norms are specific to certain conditions and not intended for individual clinical assessment. Our data on ERN distribution in young adults aims to enhance understanding of the ERN in the field.
Article
Engineering, Biomedical
Akshay Kumar, Qiang Fang, Elena Pirogova
Summary: The study aimed to determine the association between ERN signals and the psychological and cognitive states of participants. Experiments were conducted on stroke patients, measuring their subjective experience on four factors. A strong correlation was observed between the amplitude of the ERN signal and the participants' psychological and cognitive states.
BIOMEDICAL ENGINEERING ONLINE
(2021)
Article
Developmental Biology
Sally L. Cole, Enrique Cibrian, Isaac A. Mirzadegan, Alexandria Meyer
Summary: Punishment impacts the error-related negativity (ERN) in children, especially among older children and those with higher levels of anxiety.
DEVELOPMENTAL PSYCHOBIOLOGY
(2022)
Review
Behavioral Sciences
Xueqian Deng, Chen Yang, Jingyue Xu, Mengzhan Liufu, Zina Li, Juan Chen
Summary: Behavioral approaches and electrophysiology have made significant advancements in understanding human sensorimotor systems. Behavioral neuroscientists have identified implicit and explicit processes in motor learning, while electrophysiologists have discovered error-related potentials. However, there has been a lack of communication between these two lines of research. This article aims to bridge the gap by reviewing literature from both perspectives.
FRONTIERS IN INTEGRATIVE NEUROSCIENCE
(2023)
Article
Psychology, Biological
Alexandria Meyer
Summary: This review focuses on the relationship between the error-related negativity (ERN) and anxiety in children and adolescents. The ERN is increased in anxious individuals and can be reliably measured in children. The ERN predicts risk for increases in anxiety among children. Parenting styles, specifically harsh or critical parenting, may potentiate the ERN in offspring. Novel computerized intervention strategies are being developed to reduce the ERN and risk for anxiety.
Review
Psychology, Developmental
Matthew Bisset, Louise E. E. Brown, Sampada Bhide, Pooja Patel, Nardia Zendarski, David Coghill, Leanne Payne, Mark A. A. Bellgrove, Christel M. Middeldorp, Emma Sciberras
Summary: Understanding the unmet needs of healthcare consumers with ADHD is crucial for improving services, education, and research. This review examined consumer-identified needs related to ADHD clinical care or research priorities. The results revealed significant gaps in treatment beyond medication, ADHD education/training, access to clinical services and support, school accommodations, and ongoing research on treatment efficacy.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Article
Genetics & Heredity
Ditte Demontis, G. Bragi Walters, Georgios Athanasiadis, Raymond Walters, Karen Therrien, Trine Tollerup Nielsen, Leila Farajzadeh, Georgios Voloudakis, Jaroslav Bendl, Biau Zeng, Wen Zhang, Jakob Grove, Thomas D. Als, Jinjie Duan, F. Kyle Satterstrom, Jonas Bybjerg-Grauholm, Marie Baekved-Hansen, Olafur O. Gudmundsson, Sigurdur H. Magnusson, Gisli Baldursson, Katrin Davidsdottir, Gyda S. Haraldsdottir, Esben Agerbo, Gabriel E. Hoffman, Soren Dalsgaard, Joanna Martin, Marta Ribases, Dorret Boomsma, Maria Soler Artigas, Nina Roth Mota, Daniel Howrigan, Sarah E. Medland, Tetyana Zayats, Veera M. Rajagopal, Merete Nordentoft, Ole Mors, David M. Hougaard, Preben Bo Mortensen, Mark J. Daly, Stephen Faraone, Hreinn Stefansson, Panos Roussos, Barbara Franke, Thomas Werge, Benjamin M. Neale, Kari Stefansson, Anders D. Borglum
Summary: This study conducted a meta-analysis of genome-wide association studies on ADHD and identified 27 significant genetic loci associated with ADHD. They also found that these loci were enriched with genes involved in early brain development. Moreover, they discovered an increased load of rare protein-truncating variants in ADHD, implicating SORCS3 as a potential gene involved in ADHD.
Article
Psychology, Multidisciplinary
Lucy Albertella, Rebecca Kirkham, Amy B. Adler, John Crampton, Sean P. A. Drummond, Gerard J. Fogarty, James J. Gross, Leonard Zaichkowsky, Judith P. Andersen, Paul T. Bartone, Danny Boga, Jeffrey W. Bond, Tad T. Brunye, Mark J. Campbell, Liliana G. Ciobanu, Scott R. Clark, Monique F. Crane, Arne Dietrich, Tracy J. Doty, James E. Driskell, Ivar Fahsing, Stephen M. Fiore, Rhona Flin, Joachim Funke, Justine M. Gatt, P. A. Hancock, Craig Harper, Andrew Heathcote, Kristin J. Heatown, Werner F. Helsen, Erika K. Hussey, Robin C. Jackson, Sangeet Khemlani, William D. S. Killgore, Sabina Kleitman, Andrew M. Lane, Shayne Loft, Clare MacMahon, Samuele M. Marcora, Frank P. McKenna, Carla Meijen, Vanessa Moulton, Gene M. Moyle, Eugene Nalivaiko, Donna O'Connor, Dorothea O'Conor, Debra Patton, Mark D. Piccolo, Coleman Ruiz, Linda Schuecker, Ron A. Smith, Sarah J. R. Smith, Chava Sobrino, Melba Stetz, Damien Stewart, Paul Taylor, Andrew J. Tucker, Haike van Stralen, Joan N. Vickers, Troy A. W. Visser, Rohan Walker, Mark W. Wiggins, Andrew Mark Williams, Leonard Wong, Eugene Aidman, Murat Yuecel
Summary: This study aims to integrate existing knowledge in the performance field and determine the cognitive mechanisms underlying performance under pressure through expert consensus. The results identify ten important constructs, including attention, cognitive control, arousal and regulatory systems, and working memory. The expert consensus highlights the importance of standardizing cognitive assessment and informing interventions in optimizing human performance.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Psychiatry
Tracey Chau, Jeggan Tiego, Louise Brown, David Coghill, Laura Jobson, Alicia Montgomery, Cammi Murrup-Stewart, Emma Sciberras, Tim J. Silk, Megan Spencer-Smith, Nicole Stefanac, Daniel P. Sullivan, Mark A. Bellgrove
Summary: This paper examines the structural validity of the Strengths and Difficulties Questionnaire in Aboriginal and Torres Strait Islander communities. The results show that the internal consistency of the questionnaire is higher for teachers than for parents. The purported five-factor structure of the questionnaire did not hold true for both parent- and teacher-reported versions, indicating that it is not a valid measure for emotional and behavioural problems in this population.
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
(2023)
Review
Psychiatry
Tamara May, Edwina Birch, Karina Chaves, Noel Cranswick, Evelyn Culnane, Jane Delaney, Maddi Derrick, Valsamma Eapen, Chantele Edlington, Daryl Efron, Tatjana Ewais, Ingrid Garner, Michael Gathercole, Karuppiah Jagadheesan, Laura Jobson, John Kramer, Martha Mack, Marie Misso, Cammi Murrup-Stewart, Evan Savage, Emma Sciberras, Bruce Singh, Renee Testa, Lisa Vale, Alyssa Weirman, Edward Petch, Katrina Williams, Mark Bellgrove
Summary: This article provides an overview of the development and recommendations from the Australian evidence-based clinical practice guideline for ADHD. The guideline aims to promote accurate diagnosis and optimal treatment, integrating evidence, clinical expertise, and patient preferences. It includes 113 clinical recommendations for children, adolescents, and adults, covering identification, screening, diagnosis, and treatment options. Successful implementation of the guideline is anticipated to improve health outcomes for the ADHD population in Australia.
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
(2023)
Review
Behavioral Sciences
Michael C. W. English, Murray T. Maybery, Troy A. W. Visser
Summary: Most individuals have a slight bias towards visual stimuli in their left visual field (LVF), indicating right-brain specialization in visuospatial functions. Neurodevelopmental disorders can alter this bias, suggesting a connection to changes in hemispheric asymmetry. We reviewed existing literature on the link between autism and alterations in visuospatial bias, finding 13 studies that explored this issue. Evidence consistently showed reduced LVF bias in individuals with autism, particularly in studies measuring attentional bias or preference using tasks like line bisection, while findings were less conclusive for studies measuring attentional performance (e.g., reaction time). Further research and recommendations for extending this line of inquiry are needed.
Article
Clinical Neurology
Dylan Curtin, Eleanor M. Taylor, Mark A. Bellgrove, Trevor T. -J. Chong, James P. Coxon
Summary: This study found that a dopamine D2 receptor antagonist can eliminate the changes in excitatory and inhibitory cortical activity induced by exercise, which has important implications for prescribing exercise in dopaminergic dysfunction diseases.
Article
Psychology, Developmental
Ainsley Summerton, Susannah T. Bellows, Elizabeth M. Westrupp, Mark A. Stokes, David Coghill, Mark A. Bellgrove, Delyse Hutchinson, Stephen P. Becker, Glenn Melvin, Jon Quach, Daryl Efron, Argyris Stringaris, Christel M. Middeldorp, Tobias Banaschewski, Emma Sciberras
Summary: This study investigates the longitudinal associations between COVID-19 induced stress, ADHD symptoms, oppositional symptoms, and mental health outcomes in children with ADHD. The results show that baseline COVID-19 stress is associated with increased ADHD symptom severity and hyperactivity/impulsivity symptoms at 12-months. However, the associations between baseline COVID-19 stress and oppositional symptoms and negative affect at 12-months are attenuated when adjusting for baseline symptoms.
JOURNAL OF ATTENTION DISORDERS
(2023)
Article
Multidisciplinary Sciences
Andre Zugman, Luz Maria Alliende, Vicente Medel, Richard A. I. Bethlehem, Jakob Seidlitz, Grace Ringlein, Celso Arango, Aurina Arnatkeviciute, Laila Asmal, Mark Bellgrove, Vivek Benegal, Miquel Bernardo, Pablo Billeke, Jorge Bosch-Bayard, Rodrigo Bressan, Geraldo F. Busatto, Mariana N. Castro, Tiffany Chaim-Avancini, Albert Compte, Monise Costanzi, Leticia Czepielewski, Paola Dazzan, Camilo de la Fuente-Sandoval, Marta Di Forti, Covadonga M. Diaz-Caneja, Ana Maria Diaz-Zuluaga, Stefan Du Plessis, Fabio L. S. Duran, Sol Fittipaldi, Alex Fornito, Nelson B. Freimer, Ary Gadelha, Clarissa S. Gama, Ranjini Garani, Clemente Garcia-Rizo, Cecilia Gonzalez Campo, Alfonso Gonzalez-Valderrama, Salvador Guinjoan, Bharath Holla, Agustin Ibanez, Daniza Ivanovic, Andrea Jackowski, Pablo Leon-Ortiz, Christine Lochner, Carlos Lopez-Jaramillo, Hilmar Luckhoff, Raffael Massuda, Philip McGuire, Jun Miyataaaa, Romina Mizrahi, Robin Murray, Aysegul Ozerdem, Pedro M. Pan, Mara Parellada, Lebogan Phahladira, Juan P. Ramirez-Mahalu, Ramiro Reckziegel, Tiago Reis Marques, Francisco Reyes-Madrigal, Annerine Roos, Pedro Rosa, Giovanni Salum, Freda Scheffler, Gunter Schumann, Mauricio Serpa, Dan J. Stein, Angeles Tepper, Jeggan Tiego, Tsukasa Ueno, Juan Undurraga, Eduardo A. Undurrag, Pedro Valdes-Sosaooo, Isabel Valliy, Mirta Villarrealu, Toby T. Winton-Brownrrr, Nefize Yalin, Francisco Zamorano, Marcus V. Zanetti, Anderson M. Winkler, Daniel S. Pine, Sara Evans-Lacko, Nicolas A. Crossley
Summary: Gender inequality has been linked to higher mental health risks and lower academic achievement for women globally. Differences in brain structure between men and women may be partially explained by unequal exposure to harsher conditions in gender-unequal countries, leading to worse outcomes for women. A meta-analysis of MRI scans from 139 samples across 29 countries revealed that women in gender-equal countries had no differences or even thicker cortical regions, while those in countries with greater gender inequality had thinner cortices. These findings highlight the potential negative impact of gender inequality on women's brains and the need for policies based on neuroscience for gender equality.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Psychiatry
Jeggan Tiego, Kate Thompson, Aurina Arnatkeviciute, Ziarih Hawi, Amy Finlay, Kristina Sabaroedin, Beth Johnson, Mark A. Bellgrove, Alex Fornito
Summary: This study proposes a new approach to investigate the risk for developing schizophrenia-spectrum psychopathology by splitting positive and negative schizotypy into more specific subdimensions. The results indicate that genetic risk is specifically associated with delusional experiences and reduced social interest and engagement, rather than with more general schizotypy factors.
SCHIZOPHRENIA BULLETIN
(2023)
Article
Psychiatry
Marianne Oldehinkel, Jeggan Tiego, Kristina Sabaroedin, Sidhant Chopra, Shona M. Francey, Brian O'Donoghue, Vanessa Cropley, Barnaby Nelson, Jessica Graham, Lara Baldwin, Hok Pan Yuen, Kelly Allott, Mario Alvarez-Jimenez, Susy Harrigan, Christos Pantelis, Stephen J. Wood, Patrick McGorry, Mark A. Bellgrove, Alex Fornito
Summary: Psychotic illness and subclinical psychosis-like experiences are associated with dysfunction in the cortico-striatal system. This study reveals the presence of multiple overlapping functional connectivity modes in the striatum and shows that these modes are different in patients compared to controls. The findings suggest that variations in these modes may serve as neurobiological markers across the psychosis continuum.
TRANSLATIONAL PSYCHIATRY
(2023)
Article
Neurosciences
Trevor T. -J. Chong, Erika Fortunato, Mark A. Bellgrove
Summary: This study found that individuals with ADHD have lower motivation in both cognitive and physical domains, and amphetamine-based medication can increase their motivation. The results also showed that amphetamine treatment effectively restores motivation in ADHD individuals, bringing it to levels similar to healthy controls. These findings provide clear evidence for increased sensitivity to effort in individuals with ADHD and demonstrate the domain-general role of catecholamines in motivating effortful behavior.
JOURNAL OF NEUROSCIENCE
(2023)
Review
Medicine, General & Internal
Patrick Hawker, Jessica Bellamy, Catherine Mchugh, Tsz Ying Wong, Katrina Williams, Amanda Wood, Vicki Anderson, Bruce J. Tonge, Philip Ward, Emma Sciberras, Mark A. Bellgrove, Tim Silk, Ping- Lin, Valsamma Eapen
Summary: This study aims to evaluate the effectiveness of lifestyle interventions for managing the adverse effects of antipsychotic medication on physical health in children and adolescents. The researchers will conduct a systematic review of published randomized controlled trials and analyze the data quantitatively or qualitatively.
Article
Psychiatry
Sidhant Chopra, Ashlea Segal, Stuart Oldham, Alexander Holmes, Kristina Sabaroedin, Edwina R. Orchard, Shona M. Francey, Brian O'Donoghue, Vanessa Cropley, Barnaby Nelson, Jessica Graham, Lara Baldwin, Jeggan Tiego, Hok Pan Yuen, Kelly Allott, Mario Alvarez-Jimenez, Susy Harrigan, Ben D. Fulcher, Kevin Aquino, Christos Pantelis, Stephen J. Wood, Mark Bellgrove, Patrick D. Mcgorry, Alex Fornito
Summary: This study investigated gray matter changes in different stages of psychotic illness and found that brain network architecture plays a crucial role in constraining these changes. The results suggest that white matter fibers are important conduits for the spread of pathology in psychiatric disorders, and the anterior hippocampus may serve as an epicenter of early brain pathology.
Article
Psychology, Applied
James Howard, Vanessa K. Bowden, Troy Visser
Summary: Research suggests that playing action video games (AVGs) can improve cognitive performance in various areas such as attention, visual-spatial awareness, psychomotor control, and executive functioning. This study investigated if playing AVGs is associated with enhanced driving performance and spare cognitive capacity. The results revealed that participants with experience in playing AVGs performed better in driving tasks, showing better speed control, lane maintenance, and overall cognitive performance. These findings highlight the potential of video game use in improving driver safety.
TRANSPORTATION RESEARCH PART F-TRAFFIC PSYCHOLOGY AND BEHAVIOUR
(2023)
