Journal
CURRENT OPINION IN VIROLOGY
Volume 29, Issue -, Pages 8-15Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.coviro.2018.02.001
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Funding
- Sealy Center for Vaccine Development at the University of Texas Medical Branch at Galveston
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Rift Valley fever (RVF) is a zoonotic mosquito-borne bunyaviral disease associated with high abortion rates, neonatal deaths, and fetal malformations in ruminants, and mild to severe disease in humans. Outbreaks of RVF cause huge economic losses and public health impacts in endemic countries in Africa and the Arabian Peninsula. A proper vaccination strategy is important for preventing or minimizing outbreaks. Vaccination against RVF is not practiced in many countries, however, due to absence or irregular occurrences of outbreaks, despite serological evidence of RVF viral activity. Nonetheless, effective vaccination strategies, and functional national and international multi-disciplinary networks, remain crucial for ensuring availability of vaccines and supporting execution of vaccination in high risk areas for efficient response to RVF alerts and outbreaks.
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