DNA Unwinding Is the Primary Determinant of CRISPR-Cas9 Activity

Title
DNA Unwinding Is the Primary Determinant of CRISPR-Cas9 Activity
Authors
Keywords
Cas9, CRISPR, sgRNA, kinetics, R-loop, DNA cleavage
Journal
Cell Reports
Volume 22, Issue 2, Pages 359-371
Publisher
Elsevier BV
Online
2018-01-10
DOI
10.1016/j.celrep.2017.12.041

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