☆ 4.5 Editorial Material

Making progress on the global crisis of obesity and weight management

BMJ-BRITISH MEDICAL JOURNAL (2018)

Journal

BMJ-BRITISH MEDICAL JOURNAL

Volume 361, Issue -, Pages -

Publisher

BMJ PUBLISHING GROUP

DOI: 10.1136/bmj.k2538

Keywords

-

Categories

Medicine, General & Internal

Funding

Diabetes UK
European Association for the Study of Obesity
Novo Nordisk
Cambridge Weight Plan
Nutrients
Swiss Re

Ask authors/readers for more resources

Protocol

Community support

Reagent

Community support

Authors

I am an author on this paper

Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.5

Not enough ratings

Secondary Ratings

Novelty

-

Significance

-

Scientific rigor

-

Rate this paper

Recommended

Review Medicine, General & Internal

Pharmacotherapy of obesity: an update on the available medications and drugs under investigation

Marlene Chakhtoura, Rachelle Haber, Malak Ghezzawi, Caline Rhayem, Raya Tcheroyan, Christos S. Mantzoros

Summary: Obesity is a widespread health issue and medical weight management has seen significant advancements in recent years, leading to improved treatment options. Various medications have been approved for the management of obesity and there are promising novel drugs being researched.

ECLINICALMEDICINE (2023)

Add to Collection

Article Nutrition & Dietetics

Cultural Influences on the Regulation of Energy Intake and Obesity: A Qualitative Study Comparing Food Customs and Attitudes to Eating in Adults from France and the United States

Maria Carlota Dao, Sophie Thiron, Ellen Messer, Camille Sergeant, Anne Sevigne, Camille Huart, Melinda Rossi, Ilyssa Silverman, Kylie Sakaida, Pierre Bel Lassen, Charlotte Sarrat, Laura Arciniegas, Sai Krupa Das, Nicolas Gausseres, Karine Clement, Susan B. Roberts

Summary: This comparative qualitative study between France and the United States identified both common and divergent attitudes towards food culture and eating behaviors, highlighting the influence of factors such as social interactions, environmental concerns, and perceptions of natural versus processed foods. Further research is needed to develop effective interventions to address obesity in different populations.

NUTRIENTS (2021)

Add to Collection

Article Nutrition & Dietetics

A Natural Experiment Comparing the Effectiveness of the Healthy Eagles Child Weight Management Intervention in School Versus Community Settings

Melissa Little, Shirley Serber-Souza, Maryam Kebbe, Paul N. Aveyard, Susan A. Jebb

Summary: Behavioral weight management interventions like the Healthy Eagles program show small but significant benefits in reducing BMI z-scores in children, with a more pronounced effect seen in school settings compared to community settings. Particularly, participants with severe obesity and those from Black ethnic backgrounds and higher deprivation levels experienced greater reductions in BMI z-scores. Limited changes were observed in nutrition and physical activity behaviors across both settings.

NUTRIENTS (2021)

Add to Collection

Review Endocrinology & Metabolism

The impact of adult behavioural weight management interventions on mental health: A systematic review and meta-analysis

Rebecca A. Jones, Emma R. Lawlor, Jack M. Birch, Manal I. Patel, Andre O. Werneck, Erin Hoare, Simon J. Griffin, Esther M. F. van Sluijs, Stephen J. Sharp, Amy L. Ahern

Summary: Behavioral weight management interventions have positive effects on the mental health of adults with overweight or obesity, improving depression, mental health-related quality of life, and self-efficacy. However, there is no significant difference between intervention and control groups in terms of anxiety, overall quality of life, self-esteem, or stress. Further high-quality studies measuring a range of mental health outcomes over longer durations are needed to strengthen the evidence base.

OBESITY REVIEWS (2021)

Add to Collection

Article Nutrition & Dietetics

Clinical Use of the Edmonton Obesity Staging System for the Assessment of Weight Management Outcomes in People with Class 3 Obesity

Raymond Kodsi, Ritesh Chimoriya, David Medveczky, Kathy Grudzinskas, Evan Atlantis, Abd A. Tahrani, Nic Kormas, Milan K. Piya

Summary: This study aimed to evaluate the effects of an intensive non-surgical weight management program on weight loss and metabolic outcomes in patients with varying degrees of weight-related complications. The results showed that after 12 months of treatment, there was significant weight loss and improvement in metabolic parameters in both groups, regardless of the severity of complications. This suggests that intensive non-surgical weight management programs can be effective in achieving clinically meaningful weight loss in patients with severe obesity.

NUTRIENTS (2022)

Add to Collection

Article Nutrition & Dietetics

Changes in Health-Promoting Behaviors and Their Association with Weight Loss, Retention, and Engagement on a Digital Program: Prospective Study

Heather Behr, Sydney Earl, Annabell Suh Ho, Jihye Lee, Ellen Siobhan Mitchell, Meaghan McCallum, Christine N. May, Andreas Michaelides

Summary: Health-promoting lifestyle behaviors are associated with disease mortality reduction and improved well-being. This study examined the changes in health-promoting behaviors and their associations with weight loss, retention, and engagement in a digital weight-management program. Participants lost a significant amount of weight and reported improved health-promoting behaviors. Learned health-promoting behaviors were better predictors of retention and program engagement. The findings highlight the potential benefits of digital weight management interventions.

NUTRIENTS (2022)

Add to Collection

Review Nutrition & Dietetics

The Impact Once-Weekly Semaglutide 2.4 mg Will Have on Clinical Practice: A Focus on the STEP Trials

Khaled Alabduljabbar, Werd Al-Najim, Carel W. le Roux

Summary: Obesity is a complex and chronic disease that can be managed with lifestyle changes and pharmacologic interventions. The Semaglutide Treatment Effect in People with Obesity (STEP) program has shown that high-dose 2.4 mg semaglutide is effective in reducing body weight among patients with obesity. However, it may cause gastrointestinal-related side effects.

NUTRIENTS (2022)

Add to Collection

Article Medicine, General & Internal

Global Inequity in Diabetes 2 Interventions to address global inequity in diabetes: international progress

Ashby F. Walker, Sian Graham, Louise Maple-Brown, Leonard E. Egede, Jennifer A. Campbell, Rebekah J. Walker, Alisha N. Wade, Jean Claude Mbanya, Judith A. Long, Chittaranjan Yajnik, Nihal Thomas, Osagie Ebekozien, Oriyomi Odugbesan, Linda A. Dimeglio, Shivani Agarwal

Summary: Diabetes is a serious chronic disease that disproportionately affects certain communities based on socioeconomic, gender, racial, and ethnic factors. This article emphasizes the need to address the broader social context and systems in order to achieve equity in diabetes care and outcomes on a global scale. It presents best practice approaches and action plans to target diabetes equity, and showcases international examples of addressing diabetes inequity within a larger social context.

LANCET (2023)

Add to Collection

Article Health Care Sciences & Services

Weight Loss and Usage of an Online Commercial Weight Loss Program (the CSIRO Total Wellbeing Diet Online) Delivered in an Everyday Context: Five-Year Evaluation in a Community Cohort

Gilly A. Hendrie, Danielle L. Baird, Emily Brindal, Gemma Williams, Jennie Brand-Miller, Beverly Muhlhausler

Summary: This study analyzed data from the CSIRO Total Wellbeing Diet Online program, finding an average weight loss of 2.8 kg, with 43% of stayers losing 5% or more, and an average of 4.9 kg lost. Platform usage was identified as the strongest predictor of weight loss.

JOURNAL OF MEDICAL INTERNET RESEARCH (2021)

Add to Collection

Review Endocrinology & Metabolism

A systematic review of inequalities in the uptake of, adherence to, and effectiveness of behavioral weight management interventions in adults

Jack M. Birch, Rebecca A. Jones, Julia Mueller, Matthew D. McDonald, Rebecca Richards, Michael P. Kelly, Simon J. Griffin, Amy L. Ahern

Summary: This study conducted a systematic review on inequalities in behavioral weight management interventions trials, finding that most trials did not show an inequality gradient. However, when inequalities were observed, those with more advantages tended to perform better. Alternative methods of data synthesis may help in understanding inequalities in such interventions.

OBESITY REVIEWS (2022)

Add to Collection

Review Endocrinology & Metabolism

Changing the global obesity narrative to recognize and reduce weight stigma: A position statement from the World Obesity Federation

Sarah Nutter, Laura A. Eggerichs, Taniya S. Nagpal, Ximena Ramos Salas, Christine Chin Chea, Shubo Saiful, Johanna Ralston, Olivia Barata-Cavalcanti, Claudia Batz, Louise A. Baur, Susie Birney, Sheree Bryant, Kent Buse, Michelle I. Cardel, Aastha Chugh, Ada Cuevas, Mychelle Farmer, Allison Ibrahim, Ishu Kataria, Catherine Kotz, Ted Kyle, Sara le Brocq, Vicki Mooney, Clare Mullen, Joe Nadglowski, Margot Neveux, Karin Papapietro, Jaynaide Powis, Rebecca M. Puhl, Bernardo Rea Ruanova, Jessica F. Saunders, Fatima Cody Stanford, Ogweno Stephen, Kwang Wei Tham, Agbo Urudinachi, Lesly Vejar-Renteria, Danielle Walwyn, John Wilding, Saifullah Yusop

Summary: This article discusses the definition and significance of weight stigma and presents nine recommendations for reducing harmful obesity narratives on a global scale.

OBESITY REVIEWS (2023)

Add to Collection

Article Engineering, Environmental

Can International Nonsewered Sanitation Standards Help Solve the Global Sanitation Crisis?

Clement A. Cid, Francine Abiola, Markus Starkl

Summary: This article discusses the development and publication of two new voluntary product standards (ISO 30500 and ISO 31800) for nonsewered sanitation systems (NSSS) and fecal sludge treatment units (FSTUs), aiming to address severe global challenges in human health and the environment, as well as highlighting the connections between environmental emission thresholds, technical innovations, and sustainability aspects of NSSS and FSTUs.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2022)

Add to Collection

Article Public, Environmental & Occupational Health

36-Month Evaluation of a Weight Management Programme in Chinese Overweight and Obese Adults

Xi Yang, Kaushik Chattopadhyay, Richard Hubbard, Jia-Lin Li, Li Li, Yi Lin

Summary: A 36-month weight management programme in Ningbo, China showed that participants achieved significant initial weight loss at 3 months and maintained the weight loss during 33-month follow-ups. At 36 months, a certain percentage of participants achieved 5%, 10%, and 15% weight loss. The programme is suggested to benefit overweight and obese adults in reducing body weight and maintaining long-term weight loss.

FRONTIERS IN PUBLIC HEALTH (2021)

Add to Collection

Review Endocrinology & Metabolism

How does the food environment influence people engaged in weight management? A systematic review and thematic synthesis of the qualitative literature

Kimberley L. Neve, Anna Isaacs

Summary: The food environment plays a crucial role in weight management, making it more difficult for individuals to purchase and consume healthier foods, especially for those with low incomes. Reshaping food environments is essential for successful weight management.

OBESITY REVIEWS (2022)

Add to Collection

Review Endocrinology & Metabolism

The Influence of Single Nucleotide Polymorphisms On Body Weight Trajectory After Bariatric Surgery: A Systematic Review

Amelia Cristina Stival Duarte, Nara Rubia da Silva, Vivian Siqueira Santos Goncalves, Flavia Campos Corgosinho, Kenia Mara Baiocchi de Carvalho, Maria Aderuza Horst

Summary: This review systematically summarizes the results of studies on whether single nucleotide polymorphisms (SNPs) are good prognostic markers for body weight trajectory after bariatric surgery. The findings show that genetic factors can influence the body weight trajectory after bariatric surgery.

CURRENT OBESITY REPORTS (2023)

Add to Collection

Article Medicine, General & Internal

The triglyceride-glucose index as an adiposity marker and a predictor of fat loss induced by a low-calorie diet

Fernando Vidal-Ostos, Omar Ramos-Lopez, Ellen E. Blaak, Arne Astrup, Jose Alfredo Martinez

Summary: The study found that the TyG index is a good predictor of weight loss induced by LCD, with higher TyG values being associated with greater fat loss. Additionally, differences in TyG index between time points were positively correlated with body fat changes.

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2022)

Add to Collection

Article Endocrinology & Metabolism

Network Analyses Reveal Negative Link Between Changes in Adipose Tissue GDF15 and BMI During Dietary-induced Weight Loss

Alyssa Imbert, Nathalie Vialaneix, Julien Marquis, Julie Vion, Aline Charpagne, Sylviane Metairon, Claire Laurens, Cedric Moro, Nathalie Boulet, Ondine Walter, Gregory Lefebvre, Jorg Hager, Dominique Langin, Wim H. M. Saris, Arne Astrup, Nathalie Viguerie, Armand Valsesia

Summary: This study investigated the relationship between changes in bioclinical parameters and gene expression in adipose tissue during a weight loss intervention. The results revealed that changes in body mass index were associated with changes in the expression of genes related to inflammatory response. Additionally, several genes specific to macrophages were found to be connected to changes in GDF15 expression throughout the dietary intervention.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)

Add to Collection

Letter Nutrition & Dietetics

The cabohydrate-insulin model of obesity Reply

David S. Ludwig, Louis J. Aronne, Arne Astrup, Rafael de Cabo, Lewis C. Cantley, Mark Friedman, Steven B. Heymsfield, James D. Johnson, Janet C. King, Ronald M. Krauss, Daniel E. Lieberman, Gary Taubes, Jeff S. Volek, Eric C. Westman, Walter C. Willett, William S. Yancy, Cara B. Ebbeling

AMERICAN JOURNAL OF CLINICAL NUTRITION (2022)

Add to Collection

Letter Nutrition & Dietetics

ASN guidelines on P values Reply

John D. Sorkin, Mark Manary, Paul A. M. Smeets, Amanda J. MacFarlane, Arne Astrup, Ronald L. Prigeon, Beth B. Hogans, Jack Odle, Teresa A. Davis, Katherine L. Tucker, Christopher P. Duggan, Deirdre K. Tobias

AMERICAN JOURNAL OF CLINICAL NUTRITION (2022)

Add to Collection

Article Endocrinology & Metabolism

Genetic Predictors of Change in Waist Circumference and Waist-to-Hip Ratio With Lifestyle Intervention: The Trans-NIH Consortium for Genetics of Weight Loss Response to Lifestyle Intervention

Jeanne M. McCaffery, Kathleen A. Jablonski, Qing Pan, Arne Astrup, Malene Revsbech Christiansen, Dolores Corella, Lauren M. L. Corso, Jose C. Florez, Paul W. Franks, Christopher Gardner, Torben Hansen, Tuomas O. Kilpelainen, William C. Knowler, Jaana Lindstrom, Wim H. M. Saris, Thorkild I. A. Sorensen, Jaakko Tuomilehto, Matti Uusitupa, Rena R. Wing, Tanya Agurs-Collins

Summary: This study found that polygenic risk is associated with changes in waist circumference adjusted for BMI with lifestyle interventions, but the effects are small and not clinically significant.

DIABETES (2022)

Add to Collection

Article Endocrinology & Metabolism

Dietary carbohydrate restriction augments weight loss-induced improvements in glycaemic control and liver fat in individuals with type 2 diabetes: a randomised controlled trial

Mads N. Thomsen, Mads J. Skytte, Amirsalar Samkani, Martin H. Carl, Philip Weber, Arne Astrup, Elizaveta Chabanova, Mogens Fenger, Jan Frystyk, Bolette Hartmann, Jens J. Holst, Thomas M. Larsen, Sten Madsbad, Faidon Magkos, Henrik S. Thomsen, Steen B. Haugaard, Thure Krarup

Summary: The study indicates that moderate carbohydrate restriction in individuals with type 2 diabetes can improve glycemic control, reduce circulating and intrahepatic triglyceride levels beyond the effects of weight loss itself. This improvement may be attributed to differences in protein and fat intakes, and the quality of dietary macronutrients.

DIABETOLOGIA (2022)

Add to Collection

Article Nutrition & Dietetics

Unprocessed red meat in the dietary treatment of obesity: a randomized controlled trial of beef supplementation during weight maintenance after successful weight loss

Faidon Magkos, Sidse Rasmussen, Mads F. Hjorth, Sarah Asping, Maria Rosenkrans, Anders M. Sjodin, Arne Astrup, Nina R. W. Geiker

Summary: This study found that healthy diets containing small or large amounts of unprocessed beef had similar effects on body weight, energy metabolism, and cardiovascular risk factors during the first 3 months after clinically significant rapid weight loss.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2022)

Add to Collection

Editorial Material Nutrition & Dietetics

Does the concept of ultra-processed foods help inform dietary guidelines, beyond conventional classification systems? Debate consensus

Arne Astrup, Carlos A. Monteiro

Summary: The participants in this debate hold different views on the significance of ultra-processed food (UPF). The YES position argues that there is sufficient evidence linking UPF intake to various diseases, while the NO position contends that the concept is poorly defined and the observed associations with obesity may be confounded.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2022)

Add to Collection

Article Biochemistry & Molecular Biology

The Plasma Oxylipin Signature Provides a Deep Phenotyping of Metabolic Syndrome Complementary to the Clinical Criteria

Celine Dalle, Jeremy Tournayre, Malwina Mainka, Alicja Basiak-Rasala, Melanie Petera, Sophie Lefevre-Arbogast, Jessica Dalloux-Chioccioli, Melanie Deschasaux-Tanguy, Lucie Lecuyer, Emmanuelle Kesse-Guyot, Leopold K. Fezeu, Serge Hercberg, Pilar Galan, Cecilia Samieri, Katarzyna Zatonska, Philip C. Calder, Mads Fiil Hjorth, Arne Astrup, Andre Mazur, Justine Bertrand-Michel, Nils Helge Schebb, Andrzej Szuba, Mathilde Touvier, John W. Newman, Cecile Gladine

Summary: The oxylipin signature of patients with metabolic syndrome enhances MetS phenotyping and may ultimately help to better stratify the risk of cardiometabolic diseases.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Add to Collection

Article Nutrition & Dietetics

The New Nordic Renal Diet Induces a Pronounced Reduction of Urine Acid Excretion and Uremic Toxins in Chronic Kidney Disease Patients (Stage 3 and 4)

Nikita Misella Hansen, Peder Berg, Marianne Rix, Manan Pareek, Jens Leipziger, Anne -Lise Kamper, Arne Astrup, Mads Vaarby Sorensen, Louise Salomo

Summary: The objective of this study was to evaluate the effects of the New Nordic Renal Diet (NNRD) on metabolic acidosis and uremic toxins in patients with moderate CKD. The results showed that one week of NNRD effectively improved metabolic acidosis and reduced urinary excretion of uric acid and uremic toxins. These results provide encouragement for further investigations on the long-term renal protection effects of NNRD in patients with CKD.

JOURNAL OF RENAL NUTRITION (2023)

Add to Collection

Article Nutrition & Dietetics

Dietary protein and the glycemic index handle insulin resistance within a nutritional program for avoiding weight regain after energy-restricted induced weight loss

Fernando Vidal-Ostos, Omar Ramos-Lopez, Susan A. Jebb, Angeliki Papadaki, Andreas F. H. Pfeiffer, Teodora Handjieva-Darlenska, Marie Kunesova, Ellen E. Blaak, Arne Astrup, J. Alfredo Martinez

Summary: This study examines the impact of dietary protein and glycemic index on insulin resistance in the context of weight loss and maintenance. The results suggest that a high protein, low glycemic index diet not only helps with weight maintenance, but also improves insulin resistance.

NUTRITION & METABOLISM (2022)

Add to Collection

Article Immunology

Effects of low-calorie and different weight-maintenance diets on IgG glycome composition

Helena Deris, Petra Tominac, Frano Vuckovic, Nina Briski, Arne Astrup, Ellen E. Blaak, Gordan Lauc, Ivan Gudelj

Summary: Obesity-induced inflammation activates the adaptive immune system through changes in IgG glycosylation. Different dietary regimes for weight control after weight loss do not significantly affect IgG glycosylation, but individuals may still experience significant changes in their IgG glycome composition regardless of the diet type.

FRONTIERS IN IMMUNOLOGY (2022)

Add to Collection

Article Nutrition & Dietetics

Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial

Mads N. N. Thomsen, Mads J. J. Skytte, Amirsalar Samkani, Arne Astrup, Mogens Fenger, Jan Frystyk, Bolette Hartmann, Jens J. J. Holst, Thomas M. M. Larsen, Sten Madsbad, Faidon Magkos, Jens F. F. Rehfeld, Steen B. B. Haugaard, Thure Krarup

Summary: In this study, adults with T2D and obesity were randomly assigned to a carbohydrate-reduced high-protein diet or a conventional diabetes diet. While both groups experienced weight loss, the carbohydrate-reduced diet showed greater reductions in HbA(1c). However, there were no additional improvements in beta-cell function or glucose tolerance compared to the conventional diabetes diet.

FRONTIERS IN NUTRITION (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Susceptibility of Human Plasma N-glycome to Low-Calorie and Different Weight-Maintenance Diets

Helena Deris, Petra Tominac, Frano Vuckovic, Arne Astrup, Ellen E. Blaak, Gordan Lauc, Ivan Gudelj

Summary: The aberrant plasma protein glycosylation associated with various diseases was studied by analyzing glycomes from participants of the Diogenes study. Significant alterations in glycan structures were observed 8 weeks after the low-calorie diet, but these effects were nullified during the weight-maintenance diets period.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Add to Collection

Article Nutrition & Dietetics

A high-protein low-glycemic index diet attenuates gestational weight gain in pregnant women with obesity: the An optimized programming of healthy children (APPROACH) randomized controlled trial

Nina R. W. Geiker, Faidon Magkos, Helle Zingenberg, Jens Svare, Elizaveta Chabanova, Henrik S. Thomsen, Christian Ritz, Arne Astrup

Summary: Increasing dietary protein and reducing glycemic index during the last two trimesters of pregnancy can effectively reduce gestational weight gain and risk of complications, as well as decrease the rate of cesarean deliveries among overweight or obese pregnant women.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2022)

Add to Collection

No Data Available

© Peeref 2019-2024. All rights reserved.