Article
Immunology
Laura Sanchez-de Prada, Raul Ortiz de Lejarazu-Leonardo, Javier Castrodeza-Sanz, Eduardo Tamayo-Gomez, Jose Maria Eiros-Bouza, Ivan Sanz-Munoz
Summary: Elderly women exhibit a significantly higher humoral response against classical influenza A (H1N1), pandemic A(H1N1)pdm09, and B/Victoria lineage compared to elderly men. No significant differences were found with the A(H3N2) subtype. Sex dimorphism does not impact young adults.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Surgery
Maria Melkemichel, Sven Anders Wilhelm Bringman, Bjorn Otto Ola Widhe
Summary: The study compared the reoperation rate for recurrence of different lightweight to heavyweight meshes in open anterior mesh inguinal hernia repair. The results showed no significant difference between regular lightweight PP meshes and heavyweight meshes, while lightweight meshes with partially absorbable component had a higher risk of recurrence.
Article
Biochemistry & Molecular Biology
Shih-Fang Wu, Chih-Yao Lin, Rong-Kung Tsai, Yao-Tseng Wen, Feng-Huei Lin, Chia-Yu Chang, Ching- Shen, Shinn-Zong Lin, Horng-Jyh Harn, Tzyy-Wen Chiou, Chin-San Liu, Yan-Ting Chen, Hong-Lin Su
Summary: Research found that mitochondrial transplantation can moderately attenuate the degeneration of retinal layers in RCS rats. This result was confirmed through histological examination and OCT measurement of retina thickness. VEP analysis showed that the transmission time of electrical signals after mitochondrial transplantation was similar to the normal value. The results suggest that mitochondrial transplantation can improve the degeneration of photoreceptors in RCS rats and have potential for clinical application.
Article
Oncology
B. Danckert, N. L. Christensen, A. Z. Falborg, H. Frederiksen, G. Lyratzopoulos, S. McPhail, A. F. Pedersen, J. Ryg, L. A. Thomsen, P. Vedsted, H. Jensen
Summary: This study found that there are variations in the routes to cancer diagnosis for different age groups. Middle-aged patients are more likely to be diagnosed through referral from primary care, while older patients are more likely to be diagnosed through unplanned admissions, death certificate only, and outpatient admissions.
Article
Engineering, Multidisciplinary
Daniel van Huyssteen, Felipe Lopez Rivarola, Guillermo Etse, Paul Steinmann
Summary: The virtual element method, an extension of the finite element method, allows for arbitrary polygonal/polyhedral element geometry. This paper presents novel approaches for computing isotropic and anisotropic mesh refinement indicators suitable for the virtual element method, and compares them for two-dimensional linear elasticity on structured meshes. The contribution of the consistency and stabilization terms of the VE matrix in the context of mesh adaptivity is also investigated. The results show that the combination of refinement procedures based on the displacement and strain fields achieves the best performance, and the stabilization term can enhance adaptive refinement procedures.
COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING
(2022)
Article
Engineering, Biomedical
Rui Liang, Abigail Fisk, Gabrielle King, Leslie Meyn, Xiangwei Xiao, Pamela Moalli
Summary: This study found that polypropylene mesh implanted in the vagina induces prolonged inflammation at the mesh-tissue interface. Diabetes increases the mesh-associated inflammation in the long term, which is related to a dysregulated macrophage response.
ACTA BIOMATERIALIA
(2022)
Article
Medicine, General & Internal
Charlotte Cassagne, Francoise Perriard, Arnaud Cornille, Jennifer Salerno, Laure Panel
Summary: The aim of this study was to compare anatomical results of anterior sacrospinous ligament fixation (ASSLF) with native tissue repair and mesh repair for anterior prolapse correction at 12 months after surgery. A monocentric prospective study was conducted, and the results showed no significant difference in the Ba point position after 1 year between the two groups. However, the native tissue repair group had better correction of the apex and rectocele. Further prospective comparison with mesh suspension is needed to confirm these findings.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Sarah E. Coupland, Lance N. Sandle, Michael Osborn
Summary: This article highlights the contributions of three female Presidents of the Royal College of Pathologists in the UK and their significant impact on the field of pathology and healthcare.
FRONTIERS IN MEDICINE
(2022)
Article
Medicine, General & Internal
Chia-Ju Lin, Chih-Ku Liu, Hsiao-Yun Hsieh, Ming-Jer Chen, Ching-Pei Tsai
Summary: The modified vaginal mesh procedure using DynaMesh (R)-PR4 showed favorable outcomes with a short operation time, low recurrence rate, rare complications, and improved functional outcomes. This surgical option could be considered for anterior and apical pelvic organ prolapse in women.
Article
Ophthalmology
Elena Marshall, Matt Robertson, Satu Kam, Alison Penwarden, Paraskevi Riga, Nigel Davies
Summary: The prevalence of hydroxychloroquine retinopathy was found to be 1.6% in this study, lower than previously reported rates due to differences in diagnostic criteria. Most visual field tests were reliable and majority of them showed normal results.
Article
Obstetrics & Gynecology
Shaniel A. Bowen, Pamela D. Moalli, Steven Abramowitch, Douglas H. Luchristt, Isuzu R. Meyer, Charles S. Rardin, Heidi Harvie, Michael E. Hahn, Donna Mazloomdoost, Pooja Iyer, Benjamin Carper, Marie G. Gantz, NICHD Pelvic Floor Disorders Networ
Summary: This study analyzed magnetic resonance images to identify the factors associated with prolapse recurrence post vaginal surgery. It found that changes in vaginal angulation and position were related to surgical success.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Medicine, General & Internal
Zhi-Jing Sun, Xiu-Qi Wang, Jing-He Lang, Tao Xu, Yong-Xian Lu, Ke-Qin Hua, Jin-Song Han, Huai-Fang Li, Xiao-Wen Tong, Ping Wang, Jian-Liu Wang, Xin Yang, Xiang-Hua Huang, Pei-Shu Liu, Yan-Feng Song, Hang-Mei Jin, Jing-Yan Xie, Lu-Wen Wang, Qing-Kai Wu, Jian Gong, Yan Wang, Li-Qun Wang, Zhao-Ai Li, Hui-Cheng Xu, Zhi-Jun Xia, Li-Na Gu, Qing Liu, Lan Zhu
Summary: This study outlined the development of Chinese pelvic floor surgeries related to pelvic organ prolapse over the past 14 years and found that the rate of synthetic mesh procedures increased while that of non-mesh procedures decreased significantly. The rate of transvaginal placement of surgical mesh procedures decreased while the rate of laparoscopic sacrocolpopexy procedures increased significantly.
CHINESE MEDICAL JOURNAL
(2021)
Article
Obstetrics & Gynecology
Katherine L. Woodburn, Sarah E. Bradley, Sarah A. Ward, Karen A. Schirm, Bayley Clarke, Robert E. Gutman, Andrew I. Sokol
Summary: This study aimed to compare mesh complications and failure rates after 1 year in laparoscopic minimally invasive sacrocolpopexy (MISC) with ultralightweight mesh attached vaginally during total vaginal hysterectomy (TVH), laparoscopically if posthysterectomy (PH), or laparoscopically during supracervical hysterectomy. The results showed that the use of ultralightweight mesh attached vaginally during TVH had similar adverse events, mesh exposure rates, and failure rates to laparoscopic PH sacrocolpopexy or supracervical hysterectomy with laparoscopic mesh attachment.
JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY
(2023)
Article
Obstetrics & Gynecology
X. Hong, J. Zhao, X. Zhu, Q. Dai, H. Zhang, Y. Xuan, J. Yin, Yue Zhang, X. Yang, S. Fang, Q. Wang, H. Shen, Yiping Zhang, D. Yan, Y. Wang, Z. Peng, Ya Zhang, B. Wang, X. Ma
Summary: This study found a negative association between a poor vaginal microenvironment and women's fecundability, emphasizing the importance of assessing vaginal health during pre-pregnancy check-ups. Women with a poor vaginal microenvironment were associated with a reduction in fecundability.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Review
Geriatrics & Gerontology
Giampiero Capobianco, Illari Sechi, Narcisa Muresu, Laura Saderi, Andrea Piana, Mario Farina, Francesco Dessole, Giuseppe Virdis, Davide De Vita, Massimo Madonia, Marco Petrillo, Giovanni Sotgiu
Summary: The aim of this systematic review and meta-analysis was to compare the effectiveness of native tissue repair (NTR) versus transvaginal mesh augmentation for the repair of anterior vaginal prolapse. The results showed that mesh repair surgery had higher anatomical cure and satisfaction rates, but also had higher post-surgical and late complications.