Review
Clinical Neurology
Ruth Prieto, Laura Barrios, Jose M. Pascual
Summary: Strictly third ventricle craniopharyngiomas are a distinct subgroup of lesions that mainly affect adult male patients, presenting with headaches and psychiatric disturbances. Preoperative neuroradiological features are essential for distinguishing these tumors from other types of craniopharyngiomas.
NEUROSURGICAL REVIEW
(2022)
Article
Clinical Neurology
Jose Maria Pascual, Ruth Prieto, Rodrigo Carrasco, Laura Barrios
Summary: This study describes a narrow, hollow tubular structure called duct-like diverticulum (DV), which is found specifically in papillary craniopharyngiomas (PCPs) located within the third ventricle (3V). The presence of this structure was systematically investigated in a large number of CP cases and other 3V tumor categories. The DV sign can accurately identify the papillary CP type and define the strictly 3V topography.
NEUROSURGICAL REVIEW
(2022)
Article
Nutrition & Dietetics
Carolina Di Somma, Elisabetta Scarano, Luigi Barrea, Domenico Solari, Enrico Riccio, Rossana Arianna, Luigi Maria Cavallo, Fiammetta Romano, Elea Di Benedetto, Alice Rodriguez, Giulia de Alteriis, Annamaria Colao
Summary: The study aimed to investigate the potential association between Craniopharyngioma (CP), chronotypes, and metabolic risk profile. Results showed that patients with evening chronotype had higher blood pressure values and worse metabolic parameters than those with morning chronotype. The study suggests that alterations of chronotype might represent an additional risk factor for CP patients and a possible target for integrated management.
Article
Clinical Neurology
Jose Maria Pascual, Ruth Prieto, Rodrigo Carrasco, Laura Barrios
Summary: This study investigates the presence of a hollow recess at the midline undersurface of tumors primarily localized within the third ventricle. The presence of a basal recess represents a pathological hallmark of a subpopulation of third ventricle papillary craniopharyngiomas, indicating its diagnostic significance.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Hayato Kaida, Yuko Matsukubo, Sung-Woon Im, Nobuo Kashiwagi, Kazunari Ishii
Summary: This is a rare case report of a high-F-18-FDG-avidity papillary craniopharyngioma of the third ventricle. The patient underwent CT and MRI examinations and a solid tumor extending from the suprasellar region to the third ventricle was identified. F-18-FDG PET/CT showed high accumulation of fluorodeoxyglucose in the tumor. Diagnosis of papillary craniopharyngioma was confirmed through a transventricular endoscopic tumor biopsy.
CLINICAL NUCLEAR MEDICINE
(2023)
Editorial Material
Clinical Neurology
Zixiao Yang, Tongming Zhu, Zhen Fan, Jianping Song
Summary: We present a surgical case of a 9-year-old patient with a third ventricle nongerminomatous germ cell tumor. Surgical resection of this type of tumor is challenging as it requires efficient tumor removal with minimal blood loss while protecting the surrounding neurovascular structures.
WORLD NEUROSURGERY
(2022)
Article
Endocrinology & Metabolism
Daisy Duan, Leen Wehbeh, Debraj Mukherjee, Amir H. Hamrahian, Fausto J. Rodriguez, Sachin Gujar, Adham M. Khalafallah, Camille Hage, Patrizio Caturegli, Gary L. Gallia, Rexford S. Ahima, Nisa M. Maruthur, Roberto Salvatori
Summary: In adult-onset craniopharyngioma (AOCP) patients, postoperative weight and BMI tend to increase, with a simultaneous rise in the obesity rate. Some patients experience significant weight gain after surgery, especially those with 3 or more hormonal deficiencies postoperatively.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Clinical Neurology
Youngbeom Seo, Yong Hwy Kim, Jung Hee Kim, Doo-Sik Kong, Yun-Sik Dho, Ho Kang, Kyung-Min Kim, Jin Wook Kim, Chul-Kee Park
Summary: This retrospective study analyzed the surgical and clinical outcomes of 82 patients with tumors in or invading the third ventricle who underwent treatment using the endoscopic endonasal approach (EEA). The study found that EEA is a safe and effective treatment modality for tumors in the third ventricle, but further research with more cases and long-term follow-up is needed to confirm its clinical efficacy.
JOURNAL OF CLINICAL NEUROSCIENCE
(2021)
Article
Neurosciences
Marios Theologou, Konstantinos Kouskouras, Konstantinos Natsis, Panagiotis Varoutis, Eleni Zaggelidou, Christos Tsonidis
Summary: This study conducted microanatomical measurements on 25 cadaver brains and obtained multiple microanatomical parameters and correlations, which are expected to contribute to the improvement of Endoscopic Third Ventriculostomy (ETV) safety.
Article
Endocrinology & Metabolism
Wei Wu, Quanya Sun, Xiaoming Zhu, Boni Xiang, Qiongyue Zhang, Qing Miao, Yongfei Wang, Yiming Li, Hongying Ye
Summary: The study found that adult-onset patients with craniopharyngioma are at risk for significant weight gain postoperatively, especially those with lower preoperative BMI and the adamantinomatous subtype. The prevalence of HO after craniopharyngioma surgery is relatively high, with only preoperative BMI identified as an independent risk factor for postoperative HO.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Clinical Neurology
Xuefei Shou, Ming Shen, Wenqiang He, Yongfei Wang
Summary: This study retrospectively analyzes the treatment method of two third ventricle craniopharyngiomas. It concludes that a combined pre-retrochiasmatic approach using an endoscopic endonasal technique can effectively expose and completely remove the tumor inside the third ventricle with minimal injury to the hypothalamus and optic nerve.
ACTA NEUROCHIRURGICA
(2022)
Article
Oncology
Lei Cao, Wentao Wu, Jie Kang, Hui Qiao, Xiaocui Yang, Jiwei Bai, Haibo Zhu, Yazhuo Zhang, Songbai Gui
Summary: The TLTA approach is an effective method for treating tumors extending into the third ventricle, especially for craniopharyngiomas. It is important to have a sound understanding of the major strengths and limitations of this approach, as well as strategies for complication avoidance, for safe and effective application.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Shaoyang Li, Bowen Wu, Yingqun Xiao, Jie Wu, Le Yang, Chenxing Yang, Zhongjian Huang, Chengbin Pan, Minde Li, Youqing Yang, Bin Tang, Shenhao Xie, Xiao Wu, Suyue Zheng, Chunliang Wang, Tao Hong
Summary: This study investigated the relationships between craniopharyngiomas (CPs) and contiguous structures, as well as the origin of the tumor. The results showed that CPs only invade a certain part of the hypothalamic-pituitary axis, and the finger-like protrusions (FP) may be the tumor origin.
JOURNAL OF NEURO-ONCOLOGY
(2022)
Article
Clinical Neurology
Loay Shoubash, Ehab El Refaee, Marc Matthes, Joerg Baldauf, Henry W. S. Schroeder
Summary: The endoscopic transcortical-transventricular approach is safe and convenient for managing cystic lesions in the third ventricle, including craniopharyngiomas. This minimally invasive approach is increasingly recognized as useful in treating craniopharyngiomas extending into the third ventricle.
OPERATIVE NEUROSURGERY
(2023)
Review
Clinical Neurology
Chandrashekhar Deopujari, Sanjay Behari, Krishna Shroff, Ashutosh Kumar, Bhushan Thombre, Vikram Karmarkar, Chandan Mohanty
Summary: This study retrospectively analyzed the clinical presentation, treatment, and surgical outcomes of 25 patients with intraventricular craniopharyngiomas. The results showed that these lesions typically present with headaches, visual complaints, and endocrinopathies, and their deep-seated location requires minimally invasive endoscopic-assisted surgery for excision. The thin-walled cystic lesions may present challenges for complete excision, but overall, these lesions respond well to radiotherapy for a favorable long-term outcome.
FRONTIERS IN NEUROLOGY
(2021)
Article
Pathology
Jose M. Pascual, Ruth Prieto, Maria Rosdolsky, Verena Hofecker, Sewan Strauss, Eduard Winter, Walter Ulrich
Letter
Clinical Neurology
Ruth Prieto, Jose Maria Pascual
JOURNAL OF NEUROSURGERY
(2020)
Article
Clinical Neurology
Ruth Prieto, Jose Maria Pascual, Laura Barrios
JOURNAL OF NEUROSURGERY
(2020)
Article
Clinical Neurology
Ruth Prieto, Jose Maria Pascual
Summary: This paper analyzes the decision-making process of Dr. Harvey Cushing in dealing with a challenging case, demonstrating his professional dedication and unwavering determination to save lives.
JOURNAL OF NEUROSURGERY
(2021)
Letter
Neurosciences
Jose M. Pascual, Ruth Prieto, Ines Castro-Dufourny, Rodrigo Carrasco, Laura Barrios
Letter
Endocrinology & Metabolism
Jose M. Pascual, Ruth Prieto
NEUROENDOCRINOLOGY
(2022)
Letter
Clinical Neurology
Rodrigo Carrasco Moro, Jose M. Pascual
ACTA NEUROCHIRURGICA
(2022)
Letter
Clinical Neurology
Jose Maria Pascual, Ruth Prieto
CLINICAL NEUROPATHOLOGY
(2021)
Review
Clinical Neurology
Ruth Prieto, Laura Barrios, Jose M. Pascual
Summary: Strictly third ventricle craniopharyngiomas are a distinct subgroup of lesions that mainly affect adult male patients, presenting with headaches and psychiatric disturbances. Preoperative neuroradiological features are essential for distinguishing these tumors from other types of craniopharyngiomas.
NEUROSURGICAL REVIEW
(2022)
Article
Endocrinology & Metabolism
Ruth Prieto, Laura Barrios, Jose M. Pascual
Summary: This study systematically analyzes the relationship between the topography of papillary craniopharyngiomas (PCPs) and symptoms related to hypothalamic dysfunction. The results show that the location of the lesion has a significant impact on hypothalamic-related symptoms, types of hypothalamic attachments, and tumor recurrence rate.
NEUROENDOCRINOLOGY
(2022)
Article
Clinical Neurology
Jose Maria Pascual, Ruth Prieto, Rodrigo Carrasco, Laura Barrios
Summary: This study investigates the presence of a hollow recess at the midline undersurface of tumors primarily localized within the third ventricle. The presence of a basal recess represents a pathological hallmark of a subpopulation of third ventricle papillary craniopharyngiomas, indicating its diagnostic significance.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
(2022)
Article
Oncology
Jose Maria Pascual, Ruth Prieto
FRONTIERS IN ONCOLOGY
(2022)
Article
Clinical Neurology
J. M. Pascual, R. Carrasco, L. Barrios, R. Prieto
Summary: The presence of a duct-like recess at the infundibular portion of a third ventricle tumor represents a distinctive hallmark of papillary craniopharyngiomas that can be used as a simple MR imaging sign to reliably diagnose these lesions.
AMERICAN JOURNAL OF NEURORADIOLOGY
(2022)
Article
Clinical Neurology
Jose Maria Pascual, Ruth Prieto, Rodrigo Carrasco, Laura Barrios
Summary: This study describes a narrow, hollow tubular structure called duct-like diverticulum (DV), which is found specifically in papillary craniopharyngiomas (PCPs) located within the third ventricle (3V). The presence of this structure was systematically investigated in a large number of CP cases and other 3V tumor categories. The DV sign can accurately identify the papillary CP type and define the strictly 3V topography.
NEUROSURGICAL REVIEW
(2022)
Letter
Clinical Neurology
Ruth Prieto, Jose Maria Pascual
JOURNAL OF NEUROSURGERY
(2021)
Article
Clinical Neurology
Guilu He, Jianhao Lin, Jing Ye, Fobao Huang, Changzhi Yan, Zesi Liu, Xiuming Zhou, Qiao Li, Liang Zhang
Summary: This article introduces long tunneled external ventricular drain (LTEVD), which effectively avoids multiple surgeries by connecting an external shunt valve. It allows visual control of drainage flow, prolongs catheter indwelling time, and eliminates the need for multiple surgeries.
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Vinay Suresh, H. S. Suresh, Bharath Raju, Himanshu Jindal, Ahmad Ozair
Summary: This study investigated the outcomes of postoperative discitis treated with debridement and a novel technique focused on reducing outpatient antibiotic requirement in a low- and middle-income country (LMIC) setting. The results showed that patients with medically refractory postoperative discitis potentially have good outcomes after debridement plus 2-week local antibiotic instillation in LMICs.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Beatrice C. Bono, Davide Milani, Fabio Ferreli, Simone Olei, Luca Raspagliesi, Maria Pia Tropeano, Giovanni B. Lasio, Federico Pessina
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Avi A. Gajjar, Shrey Patel, Raj Swaroop Lavadi, Rida Mitha, Rohit Prem Kumar, Tavis Taylor, Galal A. Elsayed, D. Kojo Hamilton, Nitin Agarwal
Summary: Art in neurosurgery has played a crucial role in the discipline for centuries. Medical illustrations help visualize anatomy and surgical procedures, contributing to education, surgical planning, and navigation.
WORLD NEUROSURGERY
(2024)
Article
Clinical Neurology
Joaquin Perez Zabala, Yamila Basilotta Marquez, Romina Arganaraz, Beatriz Mantese
Summary: We present a low-cost and easily accessible adaptation system for stereotactic procedures in infants. By using a headband cast technique, a stereotactic biopsy was successfully performed in a 5-month-old patient, achieving precise targeting, histopathological diagnosis, and no associated complications.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Muhammad Kusdiansah, Arnau Benet, Yosuke Suzuki, Kenichi Haraguchi, Nakao Ota, Kosumo Noda, Rokuya Tanikawa
Summary: Fusiform vertebral artery aneurysms are difficult to treat, and endovascular and open microsurgical treatments are used for different situations. This report presents a case with complex anatomy and branch involvement and describes the treatment strategy used.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Victor M. Lu
Summary: This review emphasizes four essential domains that should be considered when interpreting pediatric neurosurgical SRMAs and provides examples to ensure accurate and effective interpretation of findings in this niche.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Lapo Bonosi, Angelo Torrente, Filippo Brighina, Cateno Concetto Tito Petralia, Pietro Merlino, Chiara Avallone, Vincenzo Gulino, Roberta Costanzo, Lara Brunasso, Domenico Gerardo Iacopino, Rosario Maugeri
Summary: Corticocortical evoked potentials (CCEPs) have emerged as a valuable intraoperative monitoring technique in eloquent brain tumor surgery, aiding in preserving critical functional areas. Current research shows the potential of CCEPs in guiding surgical decision making, reducing the risk of postoperative neurological deficits, and mapping functional connectivity, but further research and standardization are needed.
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Yuchen Duan, Dagang Feng, Min Zhu, Heng Qiu, Tong Li, Zhen Chen, Leiming Jiang, Yong Huang
Summary: This study aimed to compare the effect of different Modic changes (MC) grades on the cage subsidence rate after spinal interbody fusion surgery. A meta-analysis was conducted on relevant randomized controlled trials and cohort studies. The results showed that MC may be associated with a higher cage subsidence rate. With the increase in MC grades, the incidence of subsidence decreased gradually, but it was always higher than that in the non-Modic changes (NMC). Oblique lumbar interbody fusion may be a better treatment choice for lumbar degenerative disease with MC.
WORLD NEUROSURGERY
(2024)
Editorial Material
Clinical Neurology
Brian F. Saway, Conor M. Cunningham, Mustafa Ismail, Alejandro M. Spiotta
WORLD NEUROSURGERY
(2024)
Review
Clinical Neurology
Joanna M. Roy, Michael M. Covell, Carmelo Venero Jr, Christian A. Bowers
Summary: Early exposure to neurosurgery during medical school is critical for improving recruitment into the specialty. However, about 30% of medical schools in the U.S. lack a neurosurgery program, limiting students' exposure to the field. Virtual education, facilitated by webinars during the pandemic, has advantages such as global outreach and accessibility for international medical students. This review identifies and describes 16 educational resources, serving as a guide for medical students interested in neurosurgery.
WORLD NEUROSURGERY
(2024)