Thrombopoietin knock-in augments platelet generation from human embryonic stem cells

MEIS1 Regulates Hemogenic Endothelial Generation, Megakaryopoiesis, and Thrombopoiesis in Human Pluripotent Stem Cells by Targeting TAL1 and FLI1

(2018) Hongtao Wang et al.   Stem Cell Reports

Platelet production from induced pluripotent stem cells

(2017) N. Sugimoto et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Aryl hydrocarbon receptor-dependent enrichment of a megakaryocytic precursor with a high potential to produce proplatelets

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Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond

(2016) Xiaohong Ruby Xu et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming

(2016) Thomas Moreau et al.   Nature Communications

CRISPR/Cas9-AAV Mediated Knock-in at NRL Locus in Human Embryonic Stem Cells

(2016) Xianglian Ge et al.   Molecular Therapy-Nucleic Acids

Different Effects of sgRNA Length on CRISPR-mediated Gene Knockout Efficiency

(2016) Jian-Ping Zhang et al.   Scientific Reports

MSX2 mediates entry of human pluripotent stem cells into mesendoderm by simultaneously suppressing SOX2 and activating NODAL signaling

(2015) Qingqing Wu et al.   CELL RESEARCH

Thrombopoiesis

(2015) Kenneth Kaushansky   SEMINARS IN HEMATOLOGY

Efficient Generation of Megakaryocytes From Human Induced Pluripotent Stem Cells Using Food and Drug Administration-Approved Pharmacological Reagents

(2015) Yanfeng Liu et al.   Stem Cells Translational Medicine

Integrated Biophysical and Biochemical Signals Augment Megakaryopoiesis and Thrombopoiesis in a Three-Dimensional Rotary Culture System

(2015) Yiqing Yang et al.   Stem Cells Translational Medicine

Platelet bioreactor-on-a-chip

(2014) J. N. Thon et al.   BLOOD

CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

(2014) Randall J. Platt et al.   CELL

Expandable Megakaryocyte Cell Lines Enable Clinically Applicable Generation of Platelets from Human Induced Pluripotent Stem Cells

(2014) Sou Nakamura et al.   Cell Stem Cell

Scalable Generation of Universal Platelets from Human Induced Pluripotent Stem Cells

(2014) Qiang Feng et al.   Stem Cell Reports

Correction of a Genetic Disease in Mouse via Use of CRISPR-Cas9

(2013) Yuxuan Wu et al.   Cell Stem Cell

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

(2013) Thomas Gaj et al.   TRENDS IN BIOTECHNOLOGY

Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice

(2011) Shi-Jiang Lu et al.   CELL RESEARCH

Transient activation ofc-MYCexpression is critical for efficient platelet generation from human induced pluripotent stem cells

(2010) Naoya Takayama et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors

(2008) N. Takayama et al.   BLOOD

Increased production of megakaryocytes near purity from cord blood CD34+ cells using a short two-phase culture system

(2008) Lucie Boyer et al.   JOURNAL OF IMMUNOLOGICAL METHODS