ERK inhibition promotes neuroectodermal precursor commitment by blocking self-renewal and primitive streak formation of the epiblast

β-Catenin Regulates Primitive Streak Induction through Collaborative Interactions with SMAD2/SMAD3 and OCT4

(2015) Nina S. Funa et al.   Cell Stem Cell

The roles of ERAS during cell lineage specification of mouse early embryonic development

(2015) Zhen-Ao Zhao et al.   Open Biology

OCT4 Coordinates with WNT Signaling to Pre-pattern Chromatin at the SOX17 Locus during Human ES Cell Differentiation into Definitive Endoderm

(2015) Lei Ying et al.   Stem Cell Reports

Epiblast Ground State Is Controlled by Canonical Wnt/β-Catenin Signaling in the Postimplantation Mouse Embryo and Epiblast Stem Cells

(2013) Tomoyuki Sumi et al.   PLoS One

Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells to Cardiomyocytes

(2012) Christine L. Mummery et al.   CIRCULATION RESEARCH

Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion

(2012) P. N. G. Pereira et al.   DEVELOPMENT

HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition

(2012) Wenyu Zhou et al.   EMBO JOURNAL

TGF-Beta Induced Erk Phosphorylation of Smad Linker Region Regulates Smad Signaling

(2012) Chris Hough et al.   PLoS One

Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation

(2011) Jason Wray et al.   NATURE CELL BIOLOGY

Reduced Oxygen Concentration Enhances Conversion of Embryonic Stem Cells to Epiblast Stem Cells

(2011) Toshiyuki Takehara et al.   STEM CELLS AND DEVELOPMENT

TGF-β stimulates biglycan synthesis via p38 and ERK phosphorylation of the linker region of Smad2

(2010) Micah L. Burch et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nanog Overcomes Reprogramming Barriers and Induces Pluripotency in Minimal Conditions

(2010) Thorold W. Theunissen et al.   CURRENT BIOLOGY

The role of FGF/Erk signaling in pluripotent cells

(2010) F. Lanner et al.   DEVELOPMENT

Nanog Is the Gateway to the Pluripotent Ground State

(2009) Jose Silva et al.   CELL

Activin/Nodal signalling maintains pluripotency by controlling Nanog expression

(2009) L. Vallier et al.   DEVELOPMENT

Klf4 reverts developmentally programmed restriction of ground state pluripotency

(2009) G. Guo et al.   DEVELOPMENT

Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells

(2009) Siqin Bao et al.   NATURE

Differentiation of Embryonic Stem Cells to Clinically Relevant Populations: Lessons from Embryonic Development

(2008) Charles E. Murry et al.   CELL

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE