Article
Engineering, Environmental
Kaiser Iqbal Wani, M. Naeem, M. Masroor A. Khan, Tariq Aftab
Summary: This study investigates the role of strigolactones (SLs) in alleviating cadmium (Cd) toxicity in Artemisia annua plants. The results show that SLs improve the photosynthetic performance and Cd tolerance by modulating the antioxidant enzyme system, protecting chloroplasts and pigments, and enhancing glandular trichome (GT) attributes.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Agriculture, Dairy & Animal Science
Yu-Huan Chiang, Yen-Cheng Lin, Sheng-Yang Wang, Yen-Pai Lee, Chih-Feng Chen
Summary: The study found that using the antimalarial herb Artemisia annua can reduce the parasite concentration of Leucocytozoon caulleryi in chicken blood, promote weight gain, and decrease mortality and disease symptoms.
Article
Biochemical Research Methods
Yuqin Gou, Fangyuan Zhang, Yueli Tang, Chunxue Jiang, Ge Bai, He Xie, Min Chen, Zhihua Liao
Summary: In this study, nootkatone was successfully synthesized in Artemisia annua using synthetic biology methods, with significantly higher yield in engineered plastids compared to cytosol. This research provides a green approach for producing nootkatone in Artemisia annua with great market potential.
ACS SYNTHETIC BIOLOGY
(2021)
Article
Plant Sciences
Sadaf-Ilyas Kayani, Qian Shen, Saeed-ur Rahman, Xueqing Fu, Yongpeng Li, Chen Wang, Danial Hassani, Kexuan Tang
Summary: AaYABBY5 was identified as a positive regulator of flavonoid biosynthesis in Artemisia annua, with overexpression leading to increases in flavonoid and anthocyanin contents.
HORTICULTURE RESEARCH
(2021)
Article
Biotechnology & Applied Microbiology
Xueqing Fu, Fangyuan Zhang, Yanan Ma, Danial Hassani, Bowen Peng, Qifang Pan, Yuhua Zhang, Zhongxiang Deng, Wenbo Liu, Jixiu Zhang, Lei Han, Dongfang Chen, Jingya Zhao, Ling Li, Xiaofen Sun, Kexuan Tang
Summary: Terpenes are the largest class of secondary metabolites in plants, playing essential roles in plant growth and development as well as having economic value. Through engineering experiments, it has been found that plants can efficiently produce high-value terpenes through photosynthesis at a low cost.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Jiao Li, Xiao-Hui Chu, Xiao-Yu Wang, Bao-Min Feng, Zong-Xia Yu
Summary: Research shows that as the plant ages, artemisinin (ART) gradually accumulates in the leaves of Artemisia annua. Analysis at the sRNA and transcriptome levels indicates that age plays a significant regulatory role in the biosynthesis of ART.
SCIENTIFIC REPORTS
(2021)
Review
Plant Sciences
Marco Zarattini, Mahsa Farjad, Alban Launay, David Cannella, Marie-Christine Soulie, Giovanni Bernacchia, Mathilde Fagard
Summary: Current environmental and climate changes significantly impact plant-pathogen interactions, with abiotic stresses affecting the expression of plant defense genes and pathogen virulence. This can lead to modifications in existing pathosystems and the emergence of new pathogens.
JOURNAL OF EXPERIMENTAL BOTANY
(2021)
Article
Plant Sciences
Md. Shofiqul Islam, Nick Krom, Taegun Kwon, Guifen Li, Malay C. Saha
Summary: This study identified differentially expressed genes in tall fescue under different temperatures through RNA-seq analysis. The results showed that there were fewer differentially expressed genes in the morning freezing conditions and more in the evening cold conditions. Additionally, the study found that the cold tolerance of tall fescue might be related to some orthologous genes of rice.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Plant Sciences
Tian-Tian Chen, Xing-Hao Yao, Hang Liu, Yong-Peng Li, Wei Qin, Xin Yan, Xiu-Yun Wang, Bo-Wen Peng, Yao-Jie Zhang, Jin Shao, Xin-Yi Hu, Qing Miao, Xue-Qing Fu, Yu-Liang Wang, Ling Li, Ke-Xuan Tang
Summary: A MADS transcription factor, AaSEP4, has been identified as a positive regulator of artemisinin biosynthesis in Artemisia annua. AaSEP4 activates the expression of GLANDULAR TRICHOME-SPECIFIC WRKY1 and directly binds to its promoter region. Overexpression of AaSEP4 significantly increases artemisinin content in A. annua, making it a potential target for enhancing artemisinin production.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Environmental Sciences
Lixiao Ni, Hanqi Wu, Cunhao Du, Xianglan Li, Yan Li, Chu Xu, Peifang Wang, Shiyin Li, Jianhua Zhang, Xuqing Chen
Summary: The research demonstrated that artemisinin inhibited the growth of Microcystis aeruginosa, leading to cell death and increased release of microcystin-LR.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Xingxing Wang, Wenjing Sun, Shiyuan Fang, Boran Dong, JinXing Li, Zongyou Lv, Wankui Li, Wansheng Chen
Summary: Artemisinin, extracted from Artemisia annua L., is an important drug for malaria treatment and has potential applications in other diseases. The regulatory mechanism of artemisinin production is still not well understood. In this study, WRKY6 was identified as a key transcription factor that binds to the promoter of the artemisinin biosynthesis gene DBR2, thereby regulating artemisinin synthesis and content during the growth cycle of A. annua.
Article
Plant Sciences
Xinyan Han, Ziyu Chen, Jinfeng Yuan, Gaorui Wang, Xiao Han, Hui Wu, Hailian Shi, Guixin Chou, Liu Yang, Xiaojun Wu
Summary: The study showed that Artemisia annua water extract (AWE) had a significant therapeutic effect on 2,4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis (AD) in mice, possibly by inhibiting Th2 type inflammatory response.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Eun Joo Jung, Anjugam Paramanantham, Hye Jung Kim, Sung Chul Shin, Gon Sup Kim, Jin-Myung Jung, Chung Ho Ryu, Soon Chan Hong, Ky Hyun Chung, Choong Won Kim, Won Sup Lee
Summary: This study elucidated the role of JNK in the anticancer effects of pKAL polyphenols on p53 wild-type HCT116 human colorectal cancer cells. The results showed that pKAL induced morphological changes and necrosis or late apoptosis through various molecular pathways. Inhibition of JNK enhanced pKAL-induced cell death through modulation of specific cellular signals despite reduced DNA damage.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Francisco J. Hernandez-Walias, Marina Garcia, Marina Moreno, Ioannis Giannoukos, Natalia Gonzalez, Eugenio Sanz-Garcia, Khouloud Necira, Tomas Canto, Francisco Tenllado
Summary: Plants develop mechanisms to enhance their immune systems after pathogen infection, resulting in increased resistance to environmental stresses. This resistance can be inherited by the progeny, making them more tolerant to stress. In virus-infected plants, tolerance to abiotic stress can be induced within the same generation and partially sustained in the progeny. The study shows that this transgenerational tolerance to abiotic stress in progeny is correlated with the level of virulence of the pathogen and involves the upregulation of stress-related genes and the involvement of 24-nt small interfering RNAs.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Plant Sciences
Rajeev Kumar, Vidya Sagar, Vivek Chandra Verma, Mala Kumari, Ranjit Singh Gujjar, Sanjay K. Goswami, Sudhir Kumar Jha, Himanshu Pandey, Abhishek Kumar Dubey, Sangeeta Srivastava, S. P. Singh, Ashutosh K. Mall, Ashwini Dutt Pathak, Hemlata Singh, Prakash Kumar Jha, P. V. Vara Prasad
Summary: Sugarcane productivity is affected globally by changing environmental scenarios, such as drought and salinity. The complex nature of plant responses to these stresses is influenced by genotype, developmental phase, stress intensity, and duration. This review summarizes the effects of drought and salinity on sugarcane growth, specifically focusing on physiological, biochemical, and metabolic responses. Mitigation strategies and the potential of plant growth-promoting bacteria are also discussed.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Microbiology
Tania Ray, Shiv S. Pandey, Alok Pandey, Madhumita Srivastava, Karuna Shanker, Alok Kalra
FRONTIERS IN MICROBIOLOGY
(2019)
Article
Microbiology
Pooja Misra, Deepamala Maji, Ashutosh Awasthi, Shiv Shanker Pandey, Anju Yadav, Alok Pandey, Dharmendra Saikia, C. S. Vivek Babu, Alok Kalra
FRONTIERS IN MICROBIOLOGY
(2019)
Article
Biotechnology & Applied Microbiology
S. Singh, S. S. Pandey, K. Shanker, A. Kalra
JOURNAL OF APPLIED MICROBIOLOGY
(2020)
Article
Environmental Sciences
Pratibha Tripathi, Puja Khare, Deepti Barnawal, Karuna Shanker, Pankaj K. Srivastava, Rudra D. Tripathi, Alok Kalra
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Agricultural Engineering
Arpita Tripathi, Ashutosh Awasthi, Suman Singh, Kritika Sah, Deepamala Maji, Vikas Kumar Patel, Rajesh Kumar Verma, Alok Kalra
INDUSTRIAL CROPS AND PRODUCTS
(2020)
Article
Environmental Sciences
Mohammad Saleem Khan, Swati Singh, Praveen Pandey, Manoj Semwal, Alok Kalra
Summary: This study focused on menthol mint crop acreage estimation in the Barabanki district of Uttar Pradesh, India, using remote sensing technologies and an adaptive algorithm. Results showed variations in menthol mint cultivation across different regions.
JOURNAL OF THE INDIAN SOCIETY OF REMOTE SENSING
(2021)
Article
Chemistry, Medicinal
Sucheta Singh, Surjeet Verma, Dharmendra K. Yadav, Anant Kumar, Rekha Tyagi, Priyanka Gupta, Dnyaneshwar U. Bawankule, Mahendra P. Darokar, Santosh K. Srivastava, Alok Kalra
Summary: The study isolated a bioactive compound alpha,beta-dehydrocurvularin from fungal endophytes of Catharanthus roseus, which showed strong inhibitory activity against methicillin-resistant Staphylococcus aureus (MRSA) and synergistic interaction with norfloxacin. Moreover, alpha,beta-dehydrocurvularin demonstrated efflux pump inhibitory potential and decreased production of inflammatory cytokines TNF-alpha and IL-6, suggesting its potential as an antimicrobial and anti-inflammatory agent.
CURRENT TOPICS IN MEDICINAL CHEMISTRY
(2021)
Article
Plant Sciences
K. Premalatha, Navya Botlagunta, D. Santhosh, Channayya Hiremath, Rajesh K. Verma, Karuna Shanker, V Sundaresan, Alok Kalra
Summary: The study investigated the use of microbial bioinoculants isolated from medicinal plants to promote the growth of Andrographis paniculata, showing positive effects on plant height, flower initiation, Andrographolide content, and herbage yield. The use of bioinoculants also contributed to reducing fertilizer expenditure and promoting synergistic interactions among bacterial isolates for plant growth, thus providing a sustainable and cost-effective approach for crop cultivation.
JOURNAL OF PLANT NUTRITION
(2021)
Article
Agricultural Engineering
Sucheta Singh, Shiv S. Pandey, Rashmi Tiwari, Alok Pandey, Karuna Shanker, Alok Kalra
Summary: This study successfully increased the content and yield of medicinally important alkaloids in Catharanthus roseus plants by developing different microbial consortia, with varying effects observed in different seasons and cultivars.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Plant Sciences
Tania Ray, Alok Pandey, Shiv S. Pandey, Sucheta Singh, Karuna Shanker, Alok Kalra
Summary: The study identified two endophytes with inhibitory effects on downy mildew in Papaver somniferum, one of which enhanced the plant's resistance to the disease by activating the salicylic acid-dependent defense pathway. The enhanced resistance was achieved by differential expression of transcripts related to signal transduction, protein modification, disease/defense proteins, transcription factors, and phytohormones in the endophyte-treated plants. Enhanced salicylic acid content was observed in the endophyte-treated plants after exposure to the pathogen, shedding light on the molecular mechanisms underlying the resistance.
PHYSIOLOGIA PLANTARUM
(2021)
Article
Plant Sciences
Maneesha Mall, Karuna Shanker, Abdul Samad, Alok Kalra, Velusamy Sundaresan, Ashutosh K. Shukla
Summary: This study investigated the impact of biotic and abiotic factors on vindoline accumulation in Catharanthus roseus, finding that allene oxide cyclase (CrAOC) plays a key role in modulating vindoline content. The expression of CrAOC showed a direct and positive correlation with vindoline accumulation, particularly with genes involved in the conversion of tabersonine to vindoline.
Article
Environmental Sciences
Pratibha Tripathi, Ranu Yadav, Paurabi Das, Asha Singh, Raghavendra Pratap Singh, Premalatha Kandasamy, Alok Kalra, Puja Khare
Summary: The study showed that inoculation of the endophytic bacterium CIMAP-A7 significantly reduced the stress induced by atrazine in Andrographis paniculata, leading to improved plant growth and reduced accumulation of atrazine in plant tissues.
ENVIRONMENTAL POLLUTION
(2021)
Article
Agricultural Engineering
Nupoor Prasad, Manoj Semwal, Alok Kalra
Summary: This study evaluates the use of hyperspectral indices to determine the optimum harvest time for Mentha arvensis winter crop. Four hyperspectral indices were identified as potential predictors for sucker traits, indicating the optimum harvesting time. The study holds importance for menthol mint farmers in generating additional income during winter months.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Environmental Sciences
R. K. Srivastava, A. K. Singh, R. P. Bansal, A. Pal, P. Khare, R. S. Sharma, S. Kumar, A. Kalra
Summary: Several Asian countries have the tradition of offering flowers, leaves, and fragrant smoke to the Gods and Goddesses at places of worship. However, the improper disposal of flower waste and burning of incense sticks cause air, soil, and water pollution. To tackle this issue, the Council of Scientific and Industrial Research-Central Institute Medicinal and Aromatic Plants (CSIR-CIMAP) in India has developed a technology to make incense sticks and fragrant cones using offered flowers and leaves, reducing environmental pollution.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2023)
Article
Green & Sustainable Science & Technology
Deepak Kumar, Praveen Kumar Sharma, Om Prakash, Shivani Chaturvedi, Suman Singh, Ch Mohan Sai Kumar, Ashween Deepak Nannaware, Alok Kalra, Prasant Kumar Rout
Summary: A green and economical process was developed to separate lignin and hemicellulose from cornmint essential oil using a two-step method. Cellulose was isolated as a solid residue, and enzymatic biotransformation of cellulose to glucose was carried out using Trichoderma fungi. Glucose was then converted to methyl levulinate under specific conditions.