Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction

Granzyme B in skin inflammation and disease

(2017) Christopher T. Turner et al.   MATRIX BIOLOGY

Granzyme B Deficiency Protects against Angiotensin II–Induced Cardiac Fibrosis

(2016) Yue Shen et al.   AMERICAN JOURNAL OF PATHOLOGY

Proteolysis by Granzyme B Enhances Presentation of Autoantigenic Peptidylarginine Deiminase 4 Epitopes in Rheumatoid Arthritis

(2016) Erika Darrah et al.   JOURNAL OF PROTEOME RESEARCH

Granzyme B mediates both direct and indirect cleavage of extracellular matrix in skin after chronic low-dose ultraviolet light irradiation

(2014) Leigh G. Parkinson et al.   AGING CELL

Diagnosis and classification of autoimmune blistering diseases

(2014) Sharon Baum et al.   AUTOIMMUNITY REVIEWS

Update on the pathogenesis of bullous pemphigoid: An autoantibody-mediated blistering disease targeting collagen XVII

(2014) Wataru Nishie   JOURNAL OF DERMATOLOGICAL SCIENCE

Generalized bullous fixed drug eruption is distinct from Stevens-Johnson syndrome/toxic epidermal necrolysis by immunohistopathological features

(2014) Yung-Tsu Cho et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Granzyme B degrades extracellular matrix and contributes to delayed wound closure in apolipoprotein E knockout mice

(2013) P R Hiebert et al.   CELL DEATH AND DIFFERENTIATION

Lichen planus and lichenoid drug-induced eruption: a histological and immunohistochemical study

(2012) Denise Lage et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Granzyme B Cleaves Decorin, Biglycan and Soluble Betaglycan, Releasing Active Transforming Growth Factor-β1

(2012) Wendy A. Boivin et al.   PLoS One

Granzyme B in injury, inflammation, and repair

(2012) Paul R. Hiebert et al.   TRENDS IN MOLECULAR MEDICINE

Neutrophil elastase cleaves the murine hemidesmosomal protein BP180/type XVII collagen and generates degradation products that modulate experimental bullous pemphigoid

(2011) Lan Lin et al.   MATRIX BIOLOGY

Granzyme B cleavage of autoantigens in autoimmunity

(2010) E Darrah et al.   CELL DEATH AND DIFFERENTIATION

T and B cells target identical regions of the non-collagenous domain 1 of type VII collagen in epidermolysis bullosa acquisita

(2010) Ralf Müller et al.   CLINICAL IMMUNOLOGY

Cleavage of Transaldolase by Granzyme B Causes the Loss of Enzymatic Activity with Retention of Antigenicity for Multiple Sclerosis Patients

(2010) B. Niland et al.   JOURNAL OF IMMUNOLOGY

Identification of granzyme B-expressing CD-8-positive T cells in lymphocytic inflammatory infiltrate in cutaneous lupus erythematosus and in dermatomyositis

(2009) M. Grassi et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Plasmin Plays a Role in the In Vitro Generation of the Linear IgA Dermatosis Antigen LADB97

(2009) Silke C. Hofmann et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma

(2009) Wendy Anne Boivin et al.   LABORATORY INVESTIGATION

Mutation analysis and characterization of COL7A1 mutations in dystrophic epidermolysis bullosa

(2008) Ningning Dang et al.   EXPERIMENTAL DERMATOLOGY

Involvement of granzyme B and granulysin in the cytotoxic response in lichen planus

(2008) M. Ammar et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Bullous Pemphigoid Autoantibodies Preferentially Recognize Phosphoepitopes in Collagen XVII

(2008) Elena P. Zimina et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY