Naturally derived Heme-Oxygenase 1 inducers attenuate inflammatory responses in human dendritic cells and T cells: relevance for psoriasis treatment

GM-CSF in murine psoriasiform dermatitis: Redundant and pathogenic roles uncovered by antibody-induced neutralization and genetic deficiency

(2017) Tatjana Scholz et al.   PLoS One

Curcumin shows excellent therapeutic effect on psoriasis in mouse model

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Suppression of human alloreactive T cells by linear tetrapyrroles; relevance for transplantation

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Cytokines in psoriasis

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Carbon monoxide impairs mitochondria-dependent endosomal maturation and antigen presentation in dendritic cells

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Oral Curcumin (Meriva) Is Effective as an Adjuvant Treatment and Is Able to Reduce IL-22 Serum Levels in Patients with Psoriasis Vulgaris

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Nrf2 Knockout Attenuates the Anti-Inflammatory Effects of Phenethyl Isothiocyanate and Curcumin

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Specific roles for dendritic cell subsets during initiation and progression of psoriasis

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Tussilagone inhibits dendritic cell functions via induction of heme oxygenase-1

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Heme Oxygenase-1 Regulates Dendritic Cell Function through Modulation of p38 MAPK-CREB/ATF1 Signaling

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The Mononuclear Phagocyte System in Homeostasis and Disease: A Role for Heme Oxygenase-1

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Carbon monoxide decreases endosome-lysosome fusion and inhibits soluble antigen presentation by dendritic cells to T cells.

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The role of IL-22 and Th22 cells in human skin diseases

(2013) Hideki Fujita   JOURNAL OF DERMATOLOGICAL SCIENCE

Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells

(2013) Roberta Foresti et al.   PHARMACOLOGICAL RESEARCH

Curcumin Inhibits Imiquimod-Induced Psoriasis-Like Inflammation by Inhibiting IL-1beta and IL-6 Production in Mice

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Th17 and Th22 cells in psoriatic arthritis and psoriasis

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Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice

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Global Epidemiology of Psoriasis: A Systematic Review of Incidence and Prevalence

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Blockage of Heme Oxygenase-1 Abrogates the Protective Effect of Regulatory T Cells on Murine Pregnancy and Promotes the Maturation of Dendritic Cells

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Go Green: The Anti-Inflammatory Effects of Biliverdin Reductase

(2012) Barbara Wegiel et al.   Frontiers in Pharmacology

Pivotal Role of Dermal IL-17-Producing γδ T Cells in Skin Inflammation

(2011) Yihua Cai et al.   IMMUNITY

IL-17 and IL-22 enhance skin inflammation by stimulating the secretion of IL-1β by keratinocytes via the ROS-NLRP3-caspase-1 pathway

(2011) Kyung-Ah Cho et al.   INTERNATIONAL IMMUNOLOGY

Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells

(2011) Kamran Ghoreschi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Upregulation of NF-E2-related factor-2-dependent glutathione by carnosol provokes a cytoprotective response and enhances cell survival

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Curcumin induces maturation-arrested dendritic cells that expand regulatory T cells in vitro and in vivo

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Naive Human T Cells Are Activated and Proliferate in Response to the Heme Oxygenase-1 Inhibitor Tin Mesoporphyrin

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Therapeutic effects of heme oxygenase-1 on psoriasiform skin lesions in guinea pigs

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Tolerogenic dendritic cells actively inhibit T cells through heme oxygenase-1 in rodents and in nonhuman primates

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Critical Regulation of Early Th17 Cell Differentiation by Interleukin-1 Signaling

(2009) Yeonseok Chung et al.   IMMUNITY

Regulation of interleukin-12/interleukin-23 production and the T-helper 17 response in humans

(2009) Lyudmila Lyakh et al.   IMMUNOLOGICAL REVIEWS

Carbon Monoxide Inhibits TLR-Induced Dendritic Cell Immunogenicity

(2009) S. Remy et al.   JOURNAL OF IMMUNOLOGY

The Heme Oxygenase-1/Carbon Monoxide Pathway Suppresses TLR4 Signaling by Regulating the Interaction of TLR4 with Caveolin-1

(2009) X. M. Wang et al.   JOURNAL OF IMMUNOLOGY

Bilirubin and glutathione have complementary antioxidant and cytoprotective roles

(2009) T. W. Sedlak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Curcumin prevents human dendritic cell response to immune stimulants

(2008) Shawna A. Shirley et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dendritic cells and cytokines in human inflammatory and autoimmune diseases

(2008) P BLANCO et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Heme oxygenase-1 mediates the anti-inflammatory effect of Curcumin within LPS-stimulated human monocytes

(2008) Hsien-Yeh Hsu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Heme oxygenase-1–derived carbon monoxide enhances the host defense response to microbial sepsis in mice

(2008) Su Wol Chung et al.   JOURNAL OF CLINICAL INVESTIGATION

Oral curcumin in the treatment of moderate to severe psoriasis vulgaris: A prospective clinical trial

(2008) Shanu Kohli Kurd et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1

(2007) E. Olatunde Farombi et al.   FOOD AND CHEMICAL TOXICOLOGY