Journal
SCIENTIFIC REPORTS
Volume 8, Issue -, Pages -Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/s41598-017-19039-6
Keywords
-
Categories
Funding
- Swiss National Science Foundation [200021-152948]
- Swiss National Science Foundation (SNF) [200021_152948] Funding Source: Swiss National Science Foundation (SNF)
Ask authors/readers for more resources
We report dielectric microsphere array-based optical super-resolution microscopy. A dielectric microsphere that is placed on a sample is known to generate a virtual image with resolution better than the optical diffraction limit. However, a limitation of such type of super-resolution microscopy is the restricted field-of-view, essentially limited to the central area of the microsphere-generated image. We overcame this limitation by scanning a micro-fabricated array of ordered microspheres over the sample using a customized algorithm that moved step-by-step a motorized stage, meanwhile the microscope-mounted camera was taking pictures at every step. Finally, we stitched together the extracted central parts of the virtual images that showed super-resolution into a mosaic image. We demonstrated 130 nm lateral resolution (similar to lambda/4) and 5 x 10(5) mu m(2) scanned surface area using a two by one array of barium titanate glass microspheres in oil-immersion environment. Our findings may serve as a basis for widespread applications of affordable optical super-resolution microscopy.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available