Characterization of human small heat shock protein HSPB1 α-crystallin domain localized mutants associated with hereditary motor neuron diseases

Specific sequences in the N-terminal domain of human small heat-shock protein HSPB6 dictate preferential hetero-oligomerization with the orthologue HSPB1

(2017) Michelle Heirbaut et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The preferential heterodimerization of human small heat shock proteins HSPB1 and HSPB6 is dictated by the N-terminal domain

(2016) Michelle Heirbaut et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins

(2016) Evgeny V. Mymrikov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macromolecular crowding: Macromolecules friend or foe

(2015) Shruti Mittal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Small heat shock proteins: Role in cellular functions and pathology

(2015) Raman Bakthisaran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Phosphomimics Destabilize Hsp27 Oligomeric Assemblies and Enhance Chaperone Activity

(2015) Blagojce Jovcevski et al.   CHEMISTRY & BIOLOGY

Mitochondrial dynamics and inherited peripheral nerve diseases

(2015) Davide Pareyson et al.   NEUROSCIENCE LETTERS

Characterization of Mutants of Human Small Heat Shock Protein HspB1 Carrying Replacements in the N-Terminal Domain and Associated with Hereditary Motor Neuron Diseases

(2015) Lydia K. Muranova et al.   PLoS One

Characterization of human small heat shock protein HspB1 that carries C-terminal domain mutations associated with hereditary motor neuron diseases

(2014) Anna S. Chalova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Small heat-shock proteins: important players in regulating cellular proteostasis

(2014) Teresa M. Treweek et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Neuropathy- and myopathy-associated mutations in human small heat shock proteins: Characteristics and evolutionary history of the mutation sites

(2014) Rainer Benndorf et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Dissecting the Functional Role of the N-Terminal Domain of the Human Small Heat Shock Protein HSPB6

(2014) Michelle Heirbaut et al.   PLoS One

Structure and properties of G84R and L99M mutants of human small heat shock protein HspB1 correlating with motor neuropathy

(2013) Victoria V. Nefedova et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Physico-chemical properties of R140G and K141Q mutants of human small heat shock protein HspB1 associated with hereditary peripheral neuropathies

(2013) Victoria V. Nefedova et al.   BIOCHIMIE

Human small heat shock proteins: Protein interactomes of homo- and hetero-oligomeric complexes: An update

(2013) André-Patrick Arrigo   FEBS LETTERS

One size does not fit all: The oligomeric states of αB crystallin

(2013) Scott P. Delbecq et al.   FEBS LETTERS

Regulated structural transitions unleash the chaperone activity of  B-crystallin

(2013) J. Peschek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Charcot–Marie–Tooth disease: frequency of genetic subtypes and guidelines for genetic testing

(2012) Sinead M Murphy et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Knock Down of Heat Shock Protein 27 (HspB1) Induces Degradation of Several Putative Client Proteins

(2012) Benjamin Gibert et al.   PLoS One

Charcot–Marie–Tooth disease and intracellular traffic

(2012) Cecilia Bucci et al.   PROGRESS IN NEUROBIOLOGY

Charcot-marie-tooth disease subtypes and genetic testing strategies

(2011) Anita S.D. Saporta et al.   ANNALS OF NEUROLOGY

Heterooligomeric complexes of human small heat shock proteins

(2011) Evgeny V. Mymrikov et al.   CELL STRESS & CHAPERONES

Three-Dimensional Structure of α-Crystallin Domain Dimers of Human Small Heat Shock Proteins HSPB1 and HSPB6

(2011) E.V. Baranova et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal Structure of R120G Disease Mutant of Human αB-Crystallin Domain Dimer Shows Closure of a Groove

(2011) A.R. Clark et al.   JOURNAL OF MOLECULAR BIOLOGY

Small Heat-Shock Protein HSPB1 Mutants Stabilize Microtubules in Charcot-Marie-Tooth Neuropathy

(2011) L. Almeida-Souza et al.   JOURNAL OF NEUROSCIENCE

Large Potentials of Small Heat Shock Proteins

(2011) Evgeny V. Mymrikov et al.   PHYSIOLOGICAL REVIEWS

Alteration of protein folding and degradation in motor neuron diseases: Implications and protective functions of small heat shock proteins

(2011) Serena Carra et al.   PROGRESS IN NEUROBIOLOGY

Expression, purification and some properties of fluorescent chimeras of human small heat shock proteins

(2011) Petr N. Datskevich et al.   PROTEIN EXPRESSION AND PURIFICATION

Increased Monomerization of Mutant HSPB1 Leads to Protein Hyperactivity in Charcot-Marie-Tooth Neuropathy

(2010) Leonardo Almeida-Souza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel HSPB1 mutation in an Italian patient with CMT2/dHMN phenotype

(2010) M. Luigetti et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function

(2010) Arthur Laganowsky et al.   PROTEIN SCIENCE

The pivotal role of the β7 strand in the intersubunit contacts of different human small heat shock proteins

(2009) Evgeny V. Mymrikov et al.   CELL STRESS & CHAPERONES

Why proteins without an α-crystallin domain should not be included in the human small heat shock protein family HSPB

(2009) Guido Kappé et al.   CELL STRESS & CHAPERONES

Phosphorylation Dependence of Hsp27 Multimeric Size and Molecular Chaperone Function

(2009) David Hayes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NADPH oxidase activator p67phox behaves in solution as a multidomain protein with semi-flexible linkers

(2009) Dominique Durand et al.   JOURNAL OF STRUCTURAL BIOLOGY

Charcot-Marie-Tooth Disease: A Clinico-genetic Confrontation

(2008) N. Barisic et al.   ANNALS OF HUMAN GENETICS

Heterooligomeric complexes formed by human small heat shock proteins HspB1 (Hsp27) and HspB6 (Hsp20)

(2008) Olesya V. Bukach et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Mutations in the HSP27 (HSPB1) gene cause dominant, recessive, and sporadic distal HMN/CMT type 2

(2008) H. Houlden et al.   NEUROLOGY

Modern analytical ultracentrifugation in protein science: A tutorial review

(2002) Jacob Lebowitz et al.   PROTEIN SCIENCE