Basal interferon signaling and therapeutic use of interferons in controlling rotavirus infection in human intestinal cells and organoids

A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection

(2017) Kapil Saxena et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unphosphorylated ISGF3 drives constitutive expression of interferon-stimulated genes to protect against viral infections

(2017) Wenshi Wang et al.   Science Signaling

Hepatitis E virus persists in the presence of a type III interferon response

(2017) Xin Yin et al.   PLoS Pathogens

Unphosphorylated ISGF3 drives constitutive expression of interferon-stimulated genes to protect against viral infections

(2017) Wenshi Wang et al.   Science Signaling

IFN regulatory factor 1 restricts hepatitis E virus replication by activating STAT1 to induce antiviral IFN-stimulated genes

(2016) Lei Xu et al.   FASEB JOURNAL

Severe gastroenteritis and acute pancreatitis following rotavirus infection in children: The age-related failure of IFN-γ?

(2016) Raffaella Mormile   IMMUNOLOGY LETTERS

Distinct Roles of Type I and Type III Interferons in Intestinal Immunity to Homologous and Heterologous Rotavirus Infections

(2016) Jian-Da Lin et al.   PLoS Pathogens

Modeling rotavirus infection and antiviral therapy using primary intestinal organoids

(2015) Yuebang Yin et al.   ANTIVIRAL RESEARCH

Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology

(2015) Kapil Saxena et al.   JOURNAL OF VIROLOGY

Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection

(2015) Pedro P Hernández et al.   NATURE IMMUNOLOGY

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

Plasmacytoid dendritic cells promote rotavirus-induced human and murine B cell responses

(2013) Emily M. Deal et al.   JOURNAL OF CLINICAL INVESTIGATION

Innate cellular responses to rotavirus infection

(2013) G. Holloway et al.   JOURNAL OF GENERAL VIROLOGY

Global burden of childhood pneumonia and diarrhoea

(2013) Christa L Fischer Walker et al.   LANCET

Global Causes of Diarrheal Disease Mortality in Children

(2013) Claudio F. Lanata et al.   PLoS One

The Battle between Rotavirus and Its Host for Control of the Interferon Signaling Pathway

(2013) Michelle M. Arnold et al.   PLoS Pathogens

Type I and Type III Interferons Drive Redundant Amplification Loops to Induce a Transcriptional Signature in Influenza-Infected Airway Epithelia

(2013) Stefania Crotta et al.   PLoS Pathogens

IL-29 is the dominant type III interferon produced by hepatocytes during acute hepatitis C virus infection

(2012) Heiyoung Park et al.   HEPATOLOGY

Innate immune response to homologous rotavirus infection in the small intestinal villous epithelium at single-cell resolution

(2012) A. Sen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An evaluation of the inhibitory effects against rotavirus infection of edible plant extracts

(2012) Karen Knipping et al.   Virology Journal

Rotavirus-induced IFN-β promotes anti-viral signaling and apoptosis that modulate viral replication in intestinal epithelial cells

(2011) Amena H Frias et al.   Innate Immunity

IFN-  determines the intestinal epithelial antiviral host defense

(2011) J. Pott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon-stimulated genes and their antiviral effector functions

(2011) John W Schoggins et al.   Current Opinion in Virology

STAT2 Mediates Innate Immunity to Dengue Virus in the Absence of STAT1 via the Type I Interferon Receptor

(2011) Stuart T. Perry et al.   PLoS Pathogens

Rotavirus induces proliferative response and augments non-specific cytotoxic activity of lymphocytes in humans

(2010) M. YASUKAWA et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Interferon-Lambda: A New Addition to an Old Family

(2010) Raymond P. Donnelly et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Intestinal epithelia activate anti-viral signaling via intracellular sensing of rotavirus structural components

(2010) A H Frias et al.   Mucosal Immunology

Rotavirus Structural Proteins and dsRNA Are Required for the Human Primary Plasmacytoid Dendritic Cell IFNα Response

(2010) Emily M. Deal et al.   PLoS Pathogens

Rotaviruses: From Pathogenesis to Vaccination

(2009) Harry B. Greenberg et al.   GASTROENTEROLOGY

Combined antiviral activity of interferon-α and RNA interference directed against hepatitis C without affecting vector delivery and gene silencing

(2009) Qiuwei Pan et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Rotavirus Antagonizes Cellular Antiviral Responses by Inhibiting the Nuclear Accumulation of STAT1, STAT2, and NF- B

(2009) G. Holloway et al.   JOURNAL OF VIROLOGY

Variation in Antagonism of the Interferon Response to Rotavirus NSP1 Results in Differential Infectivity in Mouse Embryonic Fibroblasts

(2009) N. Feng et al.   JOURNAL OF VIROLOGY

Rotavirus NSP1 Inhibits NFκB Activation by Inducing Proteasome-Dependent Degradation of β-TrCP: A Novel Mechanism of IFN Antagonism

(2009) Joel W. Graff et al.   PLoS Pathogens

Virus-specific intestinal IFN-γ producing T cell responses induced by human rotavirus infection and vaccines are correlated with protection against rotavirus diarrhea in gnotobiotic pigs

(2008) Lijuan Yuan et al.   VACCINE

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY