TDP-43 induces p53-mediated cell death of cortical progenitors and immature neurons
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Title
TDP-43 induces p53-mediated cell death of cortical progenitors and immature neurons
Authors
Keywords
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Journal
Scientific Reports
Volume 8, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-05-19
DOI
10.1038/s41598-018-26397-2
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Note: Only part of the references are listed.- Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43
- (2015) Adam K. Walker et al. ACTA NEUROPATHOLOGICA
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- (2015) Laura De Conti et al. NUCLEIC ACIDS RESEARCH
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- (2014) Carola Stribl et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2014) Nael H. Alami et al. NEURON
- The Proliferation-Quiescence Decision Is Controlled by a Bifurcation in CDK2 Activity at Mitotic Exit
- (2013) Sabrina L. Spencer et al. CELL
- Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models
- (2013) Hyung-Jun Kim et al. NATURE GENETICS
- Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis
- (2013) Shuo-Chien Ling et al. NEURON
- ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43
- (2013) E. S. Arnold et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Requirements for Stress Granule Recruitment of Fused in Sarcoma (FUS) and TAR DNA-binding Protein of 43 kDa (TDP-43)
- (2012) Eva Bentmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Endogenous TDP-43, but not FUS, contributes to stress granule assembly via G3BP
- (2012) Anaïs Aulas et al. Molecular Neurodegeneration
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- (2012) Clotilde Lagier-Tourenne et al. NATURE NEUROSCIENCE
- Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks
- (2012) Yichen Shi et al. Nature Protocols
- Endogenous TDP-43 localized to stress granules can subsequently form protein aggregates
- (2012) Sarah J. Parker et al. NEUROCHEMISTRY INTERNATIONAL
- A Modified RMCE-Compatible Rosa26 Locus for the Expression of Transgenes from Exogenous Promoters
- (2012) Jan S. Tchorz et al. PLoS One
- Homeostatic neurogenesis in the adult hippocampus does not involve amplification of Ascl1high intermediate progenitors
- (2012) Sebastian Lugert et al. Nature Communications
- TDP-43-induced Death Is Associated with Altered Regulation of BIM and Bcl-xL and Attenuated by Caspase-mediated TDP-43 Cleavage
- (2011) Hiroaki Suzuki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice
- (2011) Lionel M. Igaz et al. JOURNAL OF CLINICAL INVESTIGATION
- Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43
- (2011) Magdalini Polymenidou et al. NATURE NEUROSCIENCE
- Characterizing the RNA targets and position-dependent splicing regulation by TDP-43
- (2011) James R Tollervey et al. NATURE NEUROSCIENCE
- An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity
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- Overexpression of TDP-43 causes partially p53-dependent G2/M arrest and p53-independent cell death in HeLa cells
- (2011) Kikyo Lee et al. NEUROSCIENCE LETTERS
- Death receptor signalling in central nervous system inflammation and demyelination
- (2011) Conor Mc Guire et al. TRENDS IN NEUROSCIENCES
- Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus
- (2011) Michael J. Devine et al. Nature Communications
- TDP-43 regulates its mRNA levels through a negative feedback loop
- (2010) Youhna M Ayala et al. EMBO JOURNAL
- TDP-43: A DNA and RNA binding protein with roles in neurodegenerative diseases
- (2010) Sadaf T. Warraich et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Identification of Neuronal RNA Targets of TDP-43-containing Ribonucleoprotein Complexes
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- Cytoplasmic Mislocalization of TDP-43 Is Toxic to Neurons and Enhanced by a Mutation Associated with Familial Amyotrophic Lateral Sclerosis
- (2010) S. J. Barmada et al. JOURNAL OF NEUROSCIENCE
- Rethinking ALS: The FUS about TDP-43
- (2009) Clotilde Lagier-Tourenne et al. CELL
- TDP-43 Is a Developmentally Regulated Protein Essential for Early Embryonic Development
- (2009) Chantelle F. Sephton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
- (2009) I. Wegorzewska et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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