JMJD-1.2 controls multiple histone post-translational modifications in germ cells and protects the genome from replication stress

JMJD-5/KDM8 regulates H3K36me2 and is required for late steps of homologous recombination and genome integrity

(2017) Pier Giorgio Amendola et al.   PLoS Genetics

Direct interrogation of the role of H3K9 in metazoan heterochromatin function

(2016) Taylor J.R. Penke et al.   GENES & DEVELOPMENT

Histone H3K9 methylation is dispensable for Caenorhabditis elegans development but suppresses RNA:DNA hybrid-associated repeat instability

(2016) Peter Zeller et al.   NATURE GENETICS

Histone demethylase PHF8 promotes epithelial to mesenchymal transition and breast tumorigenesis

(2016) Peng Shao et al.   NUCLEIC ACIDS RESEARCH

New Insights into the Regulation of Heterochromatin

(2016) Jiyong Wang et al.   TRENDS IN GENETICS

A PHF8 Homolog in C. elegans Promotes DNA Repair via Homologous Recombination

(2015) Changrim Lee et al.   PLoS One

Constitutive heterochromatin formation and transcription in mammals

(2015) Nehmé Saksouk et al.   Epigenetics & Chromatin

Histone lysine methylation and chromatin replication

(2014) Carlos Rivera et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The Histone Demethylase PHF8 Governs Retinoic Acid Response in Acute Promyelocytic Leukemia

(2013) Maria Francisca Arteaga et al.   CANCER CELL

Roles of histone methyl-modifying enzymes in development and progression of cancer

(2013) Takeshi Suzuki et al.   CANCER SCIENCE

Meiotic Double-Strand Breaks Uncover and Protect against Mitotic Errors in the C. elegans Germline

(2013) Deanna Stevens et al.   CURRENT BIOLOGY

Genetic syndromes caused by mutations in epigenetic genes

(2013) María Berdasco et al.   HUMAN GENETICS

The G2/M Regulator Histone Demethylase PHF8 Is Targeted for Degradation by the Anaphase-Promoting Complex Containing CDC20

(2013) H.-J. Lim et al.   MOLECULAR AND CELLULAR BIOLOGY

Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer

(2013) Christoph Plass et al.   NATURE REVIEWS GENETICS

Mechanisms of replication fork protection: a safeguard for genome stability

(2012) Alessia Errico et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact

(2012) Joshua C. Black et al.   MOLECULAR CELL

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion

(2011) M Björkman et al.   ONCOGENE

Coordinated regulation of active and repressive histone methylations by a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans

(2010) Hanqing Lin et al.   CELL RESEARCH

C. elegans MCM-4 is a general DNA replication and checkpoint component with an epidermis-specific requirement for growth and viability

(2010) Jerome Korzelius et al.   DEVELOPMENTAL BIOLOGY

A Functional Link between the Histone Demethylase PHF8 and the Transcription Factor ZNF711 in X-Linked Mental Retardation

(2010) Daniela Kleine-Kohlbrecher et al.   MOLECULAR CELL

Conserved Antagonism between JMJD2A/KDM4A and HP1γ during Cell Cycle Progression

(2010) Joshua C. Black et al.   MOLECULAR CELL

Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair

(2010) Eva Petermann et al.   MOLECULAR CELL

PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression

(2010) Wen Liu et al.   NATURE

Maintaining genome stability at the replication fork

(2010) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Differential Localization and Independent Acquisition of the H3K9me2 and H3K9me3 Chromatin Modifications in the Caenorhabditis elegans Adult Germ Line

(2010) Jessica B. Bessler et al.   PLoS Genetics

Heterochromatic Genome Stability Requires Regulators of Histone H3 K9 Methylation

(2009) Jamy C. Peng et al.   PLoS Genetics

Dynamic protein methylation in chromatin biology

(2008) S. S. Ng et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

SAS-4 is recruited to a dynamic structure in newly forming centrioles that is stabilized by the γ-tubulin–mediated addition of centriolar microtubules

(2008) Alexander Dammermann et al.   JOURNAL OF CELL BIOLOGY

Nucleotide excision repair and the degradation of RNA pol II by the Caenorhabditis elegans XPA and Rsp5 orthologues, RAD-3 and WWP-1

(2007) Jonathan W. Astin et al.   DNA REPAIR