FoxP3 isoforms and PD-1 expression by T regulatory cells in multiple sclerosis

T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition

(2017) Enfu Hui et al.   SCIENCE

Preferential accumulation of regulatory T cells with highly immunosuppressive characteristics in breast tumor microenvironment

(2017) Azharuddin Sajid Syed Khaja et al.   Oncotarget

Human CD39hi regulatory T cells present stronger stability and function under inflammatory conditions

(2016) Jian Gu et al.   Cellular & Molecular Immunology

Alteration in regulatory T cells and programmed cell death 1-expressing regulatory T cells in active generalized vitiligo and their clinical correlation

(2015) M.K. Tembhre et al.   BRITISH JOURNAL OF DERMATOLOGY

TCR usage, gene expression and function of two distinct FOXP3+ Treg subsets within CD4+ CD25hi T cells identified by expression of CD39 and CD45RO

(2015) Lingying Ye et al.   IMMUNOLOGY AND CELL BIOLOGY

Glycolysis controls the induction of human regulatory T cells by modulating the expression of FOXP3 exon 2 splicing variants

(2015) Veronica De Rosa et al.   NATURE IMMUNOLOGY

Prognostic value of tumor-infiltrating FoxP3+ regulatory T cells in cancers: a systematic review and meta-analysis

(2015) Bin Shang et al.   Scientific Reports

Is it time to target no evident disease activity (NEDA) in multiple sclerosis?

(2015) Gavin Giovannoni et al.   Multiple Sclerosis and Related Disorders

IL-1β promotes Th17 differentiation by inducing alternative splicing of FOXP3

(2015) Reiner K. W. Mailer et al.   Scientific Reports

CD28 ligation in the absence of TCR stimulation up-regulates IL-17A and pro-inflammatory cytokines in relapsing-remitting multiple sclerosis T lymphocytes

(2014) Cristina Camperio et al.   IMMUNOLOGY LETTERS

Isoform-Specific Inhibition of ROR -Mediated Transcriptional Activation by Human FOXP3

(2014) J. Du et al.   JOURNAL OF IMMUNOLOGY

Control of alternative splicing in immune responses: many regulators, many predictions, much still to learn

(2013) Nicole M. Martinez et al.   IMMUNOLOGICAL REVIEWS

Regulatory T cells: roles of T cell receptor for their development and function

(2010) Naganari Ohkura et al.   Seminars in Immunopathology

T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-β

(2009) Luca Durelli et al.   ANNALS OF NEUROLOGY

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

CD39+Foxp3+ Regulatory T Cells Suppress Pathogenic Th17 Cells and Are Impaired in Multiple Sclerosis

(2009) J. M. Fletcher et al.   JOURNAL OF IMMUNOLOGY

CD49d provides access to "untouched" human Foxp3+ Treg free of contaminating effector cells

(2008) M. Kleinewietfeld et al.   BLOOD

Two Functional Subsets of FOXP3+ Regulatory T Cells in Human Thymus and Periphery

(2008) Tomoki Ito et al.   IMMUNITY

Induction and effector functions of TH17 cells

(2008) Estelle Bettelli et al.   NATURE

TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function

(2008) Liang Zhou et al.   NATURE

Compromised CD4+ CD25highregulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level

(2007) Koen Venken et al.   IMMUNOLOGY