Ginkgolic acid, a sumoylation inhibitor, promotes adipocyte commitment but suppresses adipocyte terminal differentiation of mouse bone marrow stromal cells

Sclt1 deficiency causes cystic kidney by activating ERK and STAT3 signaling

(2017) Jianshuang Li et al.   HUMAN MOLECULAR GENETICS

Ginkgolic acids inhibit migration in breast cancer cells by inhibition of NEMO sumoylation and NF-κB activity

(2017) Sami Hamdoun et al.   Oncotarget

Ginkgolic Acid Inhibits Invasion and Migration and TGF-β-Induced EMT of Lung Cancer Cells Through PI3K/Akt/mTOR Inactivation

(2016) Seung Ho Baek et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Ginkgolic acid suppresses the development of pancreatic cancer by inhibiting pathways driving lipogenesis

(2015) Jiguang Ma et al.   Oncotarget

Acetylation-defective mutants of Pparγ are associated with decreased lipid synthesis in breast cancer cells

(2015) Lifeng Tian et al.   Oncotarget

Small Ubiquitin-like Modifier (SUMO) Protein-specific Protease 1 De-SUMOylates Sharp-1 Protein and Controls Adipocyte Differentiation

(2014) Bingting Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emerging therapies targeting the ubiquitin proteasome system in cancer

(2014) Nathaniel M. Weathington et al.   JOURNAL OF CLINICAL INVESTIGATION

The SUMO-Specific Isopeptidase SENP3 Regulates MLL1/MLL2 Methyltransferase Complexes and Controls Osteogenic Differentiation

(2014) Arnab Nayak et al.   MOLECULAR CELL

Chondrocytes Transdifferentiate into Osteoblasts in Endochondral Bone during Development, Postnatal Growth and Fracture Healing in Mice

(2014) Xin Zhou et al.   PLoS Genetics

Sumoylation: A Regulatory Protein Modification in Health and Disease

(2013) Annette Flotho et al.   Annual Review of Biochemistry

An Essential Role of Small Ubiquitin-like Modifier (SUMO)-specific Protease 2 in Myostatin Expression and Myogenesis

(2013) Yitao Qi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

E-selectin ligand 1 regulates bone remodeling by limiting bioactive TGF-  in the bone microenvironment

(2013) T. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The SUMO Conjugating Enzyme Ubc9 Is Required for Inducing and Maintaining Stem Cell Pluripotency

(2013) Soroush Tahmasebi et al.   STEM CELLS

Ubc9 negatively regulates BMP-mediated osteoblastic differentiation in cultured cells

(2012) Akira Yukita et al.   BONE

Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ

(2012) Li Qiang et al.   CELL

SUMO-1 Regulates Body Weight and Adipogenesis via PPARγ in Male and Female Mice

(2012) Laura Mikkonen et al.   ENDOCRINOLOGY

Increased Adipogenesis in Cultured Embryonic Chondrocytes and in Adult Bone Marrow of Dominant Negative Erg Transgenic Mice

(2012) Sébastien Flajollet et al.   PLoS One

Epigenetic codes of PPARγ in metabolic disease

(2011) Shigeki Sugii et al.   FEBS LETTERS

Inhibitory effects of garcinol and pterostilbene on cell proliferation and adipogenesis in 3T3-L1 cells

(2011) Chin-Lin Hsu et al.   Food & Function

Antitumor Effects of Ginkgolic Acid in Human Cancer Cell Occur via Cell Cycle Arrest and Decrease the Bcl-2/Bax Ratio to Induce Apoptosis

(2010) Chenchen Zhou et al.   CHEMOTHERAPY

Role of UBC9 in the Regulation of the Adipogenic Program in 3T3-L1 Adipocytes

(2010) Angelo Cignarelli et al.   ENDOCRINOLOGY

Control of Adipogenesis by the SUMO-Specific Protease SENP2

(2010) S. S. Chung et al.   MOLECULAR AND CELLULAR BIOLOGY

Ginkgolic Acid Inhibits Protein SUMOylation by Blocking Formation of the E1-SUMO Intermediate

(2009) Isao Fukuda et al.   CHEMISTRY & BIOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Sumoylation and the function of CCAAT enhancer binding protein alpha (C/EBPα)

(2008) Arati Khanna-Gupta   BLOOD CELLS MOLECULES AND DISEASES

Ubc9 promotes the stability of Smad4 and the nuclear accumulation of Smad1 in osteoblast-like Saos-2 cells

(2008) Koichi Shimada et al.   BONE

Minireview: Lipid Droplets in Lipogenesis and Lipolysis

(2008) Nicole A. Ducharme et al.   ENDOCRINOLOGY

SUMOylation and De-SUMOylation: Wrestling with Life's Processes

(2008) Edward T. H. Yeh   JOURNAL OF BIOLOGICAL CHEMISTRY

Adipose triglyceride lipase regulates basal lipolysis and lipid droplet size in adipocytes

(2008) Hideaki Miyoshi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

SUMOylation of Krüppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-δ

(2008) Yumiko Oishi et al.   NATURE MEDICINE

SUMO-Specific Protease 2 Is Essential for Modulating p53-Mdm2 in Development of Trophoblast Stem Cell Niches and Lineages

(2008) Shang-Yi Chiu et al.   PLOS BIOLOGY