Knockdown of SPRY4 and SPRY4-IT1 inhibits cell growth and phosphorylation of Akt in human testicular germ cell tumours

Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor

(2017) Kevin Litchfield et al.   NATURE GENETICS

Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor

(2017) Zhaoming Wang et al.   NATURE GENETICS

Suppression of Spry4 enhances cancer stem cell properties of human MDA-MB-231 breast carcinoma cells

(2016) Hongyu Jing et al.   Cancer Cell International

Genetic changes associated with testicular cancer susceptibility

(2016) Louise C. Pyle et al.   SEMINARS IN ONCOLOGY

Sprouty4 mediates amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells

(2016) Wai-Kin So et al.   TUMOR BIOLOGY

TDRG1 functions in testicular seminoma are dependent on the PI3K/Akt/mTOR signaling pathway

(2016) Yuxin Tang et al.   OncoTargets and Therapy

Long non-coding RNA SPRY4-IT1 pormotes colorectal cancer metastasis by regulate epithelial-mesenchymal transition

(2016) Fei Shen et al.   Oncotarget

The long noncoding RNA SPRY4-IT1 increases the proliferation of human breast cancer cells by upregulating ZNF703 expression

(2015) Yongguo Shi et al.   Molecular Cancer

Targeting RTK Signaling Pathways in Cancer

(2015) Tarik Regad   Cancers

The functional characterization of long noncoding RNA SPRY4-IT1 in human melanoma cells

(2015) Joseph Mazar et al.   Oncotarget

The developing story of Sprouty and cancer

(2014) Samar Masoumi-Moghaddam et al.   CANCER AND METASTASIS REVIEWS

Validation of endogenous normalizing genes for expression analyses in adult human testis and germ cell neoplasms

(2014) T. Svingen et al.   MOLECULAR HUMAN REPRODUCTION

EZH2-mediated epigenetic suppression of long noncoding RNA SPRY4-IT1 promote s NSCLC cell proliferation and metastasis by affecting the epithelial–mesenchymal transition

(2014) M Sun et al.   Cell Death & Disease

International patterns and trends in testicular cancer incidence, overall and by histologic subtype, 1973-2007

(2014) B. Trabert et al.   Andrology

Testis Cancer: Genes, Environment, Hormones

(2014) Alberto Ferlin et al.   Frontiers in Endocrinology

International Variations and Trends in Testicular Cancer Incidence and Mortality

(2013) Ariana Znaor et al.   EUROPEAN UROLOGY

Investigation of six testicular germ cell tumor susceptibility genes suggests a parent-of-origin effect in SPRY4

(2013) Robert Karlsson et al.   HUMAN MOLECULAR GENETICS

Sprouty genes regulate proliferation and survival of human embryonic stem cells

(2013) Hady Felfly et al.   Scientific Reports

Adolescent and adult risk factors for testicular cancer

(2012) Katherine A. McGlynn et al.   Nature Reviews Urology

The Melanoma-Upregulated Long Noncoding RNA SPRY4-IT1 Modulates Apoptosis and Invasion

(2011) D. Khaitan et al.   CANCER RESEARCH

Genome-wide association studies provide new insights into the genetic basis of testicular germ-cell tumour

(2011) C. Turnbull et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Sprouty-4 Inhibits Transformed Cell Growth, Migration and Invasion, and Epithelial-Mesenchymal Transition, and Is Regulated by Wnt7A through PPAR  in Non-Small Cell Lung Cancer

(2010) M. A. Tennis et al.   MOLECULAR CANCER RESEARCH

Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer

(2009) Peter A Kanetsky et al.   NATURE GENETICS

A genome-wide association study of testicular germ cell tumor

(2009) Elizabeth A Rapley et al.   NATURE GENETICS

Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation

(2008) M. E. Dinger et al.   GENOME RESEARCH

Specific expression of long noncoding RNAs in the mouse brain

(2008) T. R. Mercer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA