Impaired Wnt signaling in dopamine containing neurons is associated with pathogenesis in a rotenone triggered Drosophila Parkinson’s disease model

Overexpression of Sir2 in the adult fat body is sufficient to extend lifespan of male and female Drosophila

(2016) Julia Hoffmann et al.   Aging-US

ORMDL deregulation increases stress responses and modulates repair pathways in Drosophila airways

(2015) Kimberley Kallsen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Pathogenesis of Parkinson disease—the gut–brain axis and environmental factors

(2015) Lisa Klingelhoefer et al.   Nature Reviews Neurology

Analysis of dopaminergic neuronal dysfunction in genetic and toxin-induced models of Parkinson's disease inDrosophila

(2014) Juan A. Navarro et al.   JOURNAL OF NEUROCHEMISTRY

The prevalence of Parkinson's disease: A systematic review and meta-analysis

(2014) Tamara Pringsheim et al.   MOVEMENT DISORDERS

Nicotine increases lifespan and rescues olfactory and motor deficits in a Drosophila model of Parkinson's disease

(2013) Raegan P. Chambers et al.   BEHAVIOURAL BRAIN RESEARCH

Uncovering novel actors in astrocyte-neuron crosstalk in Parkinson's disease: the Wnt/β-catenin signaling cascade as the common final pathway for neuroprotection and self-repair

(2013) Bianca Marchetti et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

EGFR signaling in the brain is necessary for olfactory learning in Drosophila larvae

(2013) T. Rahn et al.   LEARNING & MEMORY

The importance of Wnt signalling for neurodegeneration in Parkinson's disease

(2012) Daniel C. Berwick et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Phosphatases in SMAD regulation

(2012) David L. Bruce et al.   FEBS LETTERS

LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6

(2012) Daniel C. Berwick et al.   HUMAN MOLECULAR GENETICS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Parkinson's Disease: Genetics and Pathogenesis

(2011) Joshua M. Shulman et al.   Annual Review of Pathology-Mechanisms of Disease

Genes and pathways affected by CAG-repeat RNA-based toxicity in Drosophila

(2011) Shin-Yi Shieh et al.   HUMAN MOLECULAR GENETICS

Nucleolar Disruption in Dopaminergic Neurons Leads to Oxidative Damage and Parkinsonism through Repression of Mammalian Target of Rapamycin Signaling

(2011) C. Rieker et al.   JOURNAL OF NEUROSCIENCE

En1 and Wnt signaling in midbrain dopaminergic neuronal development

(2011) Maria TM Alves dos Santos et al.   Neural Development

What causes cell death in Parkinson's disease?

(2010) Amitabh Gupta et al.   ANNALS OF NEUROLOGY

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Chronic activation of the epithelial immune system of the fruit fly's salivary glands has a negative effect on organismal growth and induces a peculiar set of target genes

(2010) Ahmed Abdelsadik et al.   BMC GENOMICS

Gene expression profiling in progressively MPTP-lesioned macaques reveals molecular pathways associated with sporadic Parkinson's disease

(2010) Tatsuya Ohnuki et al.   BRAIN RESEARCH

Decaffeinated Coffee and Nicotine-Free Tobacco Provide Neuroprotection in Drosophila Models of Parkinson's Disease through an NRF2-Dependent Mechanism

(2010) K. Trinh et al.   JOURNAL OF NEUROSCIENCE

Dopamine-dependent neurodegeneration in Drosophila models of familial and sporadic Parkinson's disease

(2010) Florian Bayersdorfer et al.   NEUROBIOLOGY OF DISEASE

Genetic Animal Models of Parkinson's Disease

(2010) Ted M. Dawson et al.   NEURON

Behavioral consequences of dopamine deficiency in the Drosophila central nervous system

(2010) T. Riemensperger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Parkin protects dopaminergic neurons from excessive Wnt/β-catenin signaling

(2009) Nina Rawal et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

(2009) Eran Eden et al.   BMC BIOINFORMATICS

Molecular pathogenesis of Parkinson disease: insights from genetic studies

(2009) Thomas Gasser   EXPERT REVIEWS IN MOLECULAR MEDICINE

Mutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathways

(2009) Rosa M. Sancho et al.   HUMAN MOLECULAR GENETICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Maintaining the brain: insight into human neurodegeneration from Drosophila melanogaster mutants

(2009) Derek Lessing et al.   NATURE REVIEWS GENETICS

Emerging roles of Wnts in the adult nervous system

(2009) Nibaldo C. Inestrosa et al.   NATURE REVIEWS NEUROSCIENCE

Eight different types of dopaminergic neurons innervate the Drosophila mushroom body neuropil: anatomical and physiological heterogeneity

(2009) Zhengmei Mao   Frontiers in Neural Circuits

Gene expression profiling of substantia nigra dopamine neurons: further insights into Parkinson's disease pathology

(2008) Filip Simunovic et al.   BRAIN

The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease

(2008) Nibaldo C Inestrosa et al.   Molecular Neurodegeneration

Low dose rotenone treatment causes selective transcriptional activation of cell death related pathways in dopaminergic neurons in vivo

(2008) B.H. Meurers et al.   NEUROBIOLOGY OF DISEASE

Apoptosis Signal-Regulating Kinase 1 in Stress and Immune Response

(2007) Kohsuke Takeda et al.   Annual Review of Pharmacology and Toxicology