Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy
Authors
Keywords
-
Journal
Scientific Reports
Volume 8, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-05-15
DOI
10.1038/s41598-018-26347-y
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A microRNA screen reveals that elevated hepatic ectodysplasin A expression contributes to obesity-induced insulin resistance in skeletal muscle
- (2017) Motoharu Awazawa et al. NATURE MEDICINE
- Single-Dose Gene-Replacement Therapy for Spinal Muscular Atrophy
- (2017) Jerry R. Mendell et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy
- (2017) Richard S. Finkel et al. NEW ENGLAND JOURNAL OF MEDICINE
- Inhibition of autophagy delays motoneuron degeneration and extends lifespan in a mouse model of spinal muscular atrophy
- (2017) Antonio Piras et al. Cell Death & Disease
- Defective recognition of LC3B by mutant SQSTM1/p62 implicates impairment of autophagy as a pathogenic mechanism in ALS-FTLD
- (2016) Alice Goode et al. Autophagy
- Multipotency of Adult Hippocampal NSCs In Vivo Is Restricted by Drosha/NFIB
- (2016) Chiara Rolando et al. Cell Stem Cell
- miR‐132 loss de‐represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain
- (2016) Evgenia Salta et al. EMBO Molecular Medicine
- Cell-type-specific miR-431 dysregulation in a motor neuron model of spinal muscular atrophy
- (2016) Mary H. Wertz et al. HUMAN MOLECULAR GENETICS
- Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study
- (2016) Richard S Finkel et al. LANCET
- Cytoplasmic Drosha activity generated by alternative splicing
- (2016) Lisheng Dai et al. NUCLEIC ACIDS RESEARCH
- Alternative splicing affects the subcellular localization of Drosha
- (2016) Steffen Link et al. NUCLEIC ACIDS RESEARCH
- Re-evaluation of the roles ofDROSHA,Exportin 5, andDICERin microRNA biogenesis
- (2016) Young-Kook Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Altered Levels of MicroRNA-9, -206, and -132 in Spinal Muscular Atrophy and Their Response to Antisense Oligonucleotide Therapy
- (2016) Francesco Catapano et al. Molecular Therapy-Nucleic Acids
- Developing therapies for spinal muscular atrophy
- (2015) Mary H. Wertz et al. Annals of the New York Academy of Sciences
- Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor
- (2015) M. E. Jonsson et al. DEVELOPMENT
- Dysregulated miRNA biogenesis downstream of cellular stress and ALS-causing mutations: a new mechanism for ALS
- (2015) A. Emde et al. EMBO JOURNAL
- Investigational therapies for the treatment of spinal muscular atrophy
- (2015) Anna Kaczmarek et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- An mTORC1-Mdm2-Drosha Axis for miRNA Biogenesis in Response to Glucose- and Amino Acid-Deprivation
- (2015) Peiying Ye et al. MOLECULAR CELL
- Stress Induces p38 MAPK-Mediated Phosphorylation and Inhibition of Drosha-Dependent Cell Survival
- (2015) Qian Yang et al. MOLECULAR CELL
- Compromised autophagy and neurodegenerative diseases
- (2015) Fiona M. Menzies et al. NATURE REVIEWS NEUROSCIENCE
- Loss of motoneuron-specific microRNA-218 causes systemic neuromuscular failure
- (2015) N. D. Amin et al. SCIENCE
- SMN regulates axonal local translation via miR-183/mTOR pathway
- (2014) Min Jeong Kye et al. HUMAN MOLECULAR GENETICS
- Autophagy dysregulation in cell culture and animals models of spinal muscular atrophy
- (2014) Sara K. Custer et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- The Neuroprotective Drug Riluzole Acts via Small Conductance Ca2+-Activated K+ Channels to Ameliorate Defects in Spinal Muscular Atrophy Models
- (2013) M. Dimitriadi et al. JOURNAL OF NEUROSCIENCE
- Survival motor neuron protein reduction deregulates autophagy in spinal cord motoneurons in vitro
- (2013) A Garcera et al. Cell Death & Disease
- Altered microRNA expression profile in amyotrophic lateral sclerosis: a role in the regulation of NFL mRNA levels
- (2013) Danae Campos-Melo et al. Molecular Brain
- FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment
- (2012) Mariangela Morlando et al. EMBO JOURNAL
- Motor Neuron-specific Disruption of Proteasomes, but Not Autophagy, Replicates Amyotrophic Lateral Sclerosis
- (2012) Yoshitaka Tashiro et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neuronal Stimulation Induces Autophagy in Hippocampal Neurons That Is Involved in AMPA Receptor Degradation after Chemical Long-Term Depression
- (2012) M. Shehata et al. JOURNAL OF NEUROSCIENCE
- Drosha regulates neurogenesis by controlling Neurogenin 2 expression independent of microRNAs
- (2012) Philip Knuckles et al. NATURE NEUROSCIENCE
- TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes
- (2012) Y. Kawahara et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SQSTM1 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2011) Faisal Fecto ARCHIVES OF NEUROLOGY
- Frontotemporal Dementia Caused by CHMP2B Mutations
- (2011) A. M. Isaacs et al. Current Alzheimer Research
- The Survival of Motor Neuron (SMN) Protein Interacts with the mRNA-Binding Protein HuD and Regulates Localization of Poly(A) mRNA in Primary Motor Neuron Axons
- (2011) C. Fallini et al. JOURNAL OF NEUROSCIENCE
- Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model
- (2011) Yimin Hua et al. NATURE
- The biogenesis and characterization of mammalian microRNAs of mirtron origin
- (2011) Christopher R. Sibley et al. NUCLEIC ACIDS RESEARCH
- Depletion of key protein components of the RISC pathway impairs pre-ribosomal RNA processing
- (2011) Xue-hai Liang et al. NUCLEIC ACIDS RESEARCH
- Glycogen Synthase Kinase 3 Beta (GSK3β) Phosphorylates the RNAase III Enzyme Drosha at S300 and S302
- (2011) Xiaoli Tang et al. PLoS One
- NMDA Mediated Contextual Conditioning Changes miRNA Expression
- (2011) Min Jeong Kye et al. PLoS One
- Autophagy is activated by proteasomal inhibition and involved in aggresome clearance in cultured astrocytes
- (2010) Sven B. Jänen et al. GLIA
- SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy
- (2010) Markus Riessland et al. HUMAN MOLECULAR GENETICS
- A novel pathway regulates memory and plasticity via SIRT1 and miR-134
- (2010) Jun Gao et al. NATURE
- Phosphorylation of the RNase III enzyme Drosha at Serine300 or Serine302 is required for its nuclear localization
- (2010) Xiaoli Tang et al. NUCLEIC ACIDS RESEARCH
- Autophagy in neurodegenerative disorders: pathogenic roles and therapeutic implications
- (2010) Rebecca Banerjee et al. TRENDS IN NEUROSCIENCES
- Posttranscriptional Crossregulation between Drosha and DGCR8
- (2009) Jinju Han et al. CELL
- Schizophrenia is associated with an increase in cortical microRNA biogenesis
- (2009) N J Beveridge et al. MOLECULAR PSYCHIATRY
- The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease
- (2008) Mark M.W. Chong et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Autophagy fights disease through cellular self-digestion
- (2008) Noboru Mizushima et al. NATURE
- Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model
- (2008) Kimberly L Stark et al. NATURE GENETICS
- MiR-10 Represses HoxB1a and HoxB3a in Zebrafish
- (2008) Joost M. Woltering et al. PLoS One
- An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP
- (2008) Gary A. Wayman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2008) J. Sreedharan et al. SCIENCE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started