Loss of tolerance to gut immunity protein, glycoprotein 2 (GP2) is associated with progressive disease course in primary sclerosing cholangitis

Gut barrier failure biomarkers are associated with poor disease outcome in patients with primary sclerosing cholangitis

(2017) Tamas Tornai et al.   WORLD JOURNAL OF GASTROENTEROLOGY

The Gut-Liver Axis in Primary Sclerosing Cholangitis

(2016) Bertus Eksteen   Clinics in Liver Disease

Mannose-derived FimH antagonists: a promising anti-virulence therapeutic strategy for urinary tract infections and Crohn’s disease

(2016) Laurel K. Mydock-McGrane et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Repurposing Escherichia coli antiadhesives in Crohn's disease

(2016) Sébastien G Gouin   Future Medicinal Chemistry

Anti-GP2 IgA autoantibodies are associated with poor survival and cholangiocarcinoma in primary sclerosing cholangitis

(2016) Sebastian Torben Jendrek et al.   GUT

Serologic Anti-GP2 Antibodies Are Associated with Genetic Polymorphisms, Fibrostenosis, and Need for Surgical Resection in Crohnʼs Disease

(2016) Frauke Degenhardt et al.   INFLAMMATORY BOWEL DISEASES

Autoreactive Iga Antibodies against the Pancreatic Major Glycoprotein 2 are Associated with Primary Sclerosing Cholangitis and Related Biliary Tract Cancer

(2016) S.T. Jendrek et al.   JOURNAL OF HEPATOLOGY

Primary Sclerosing Cholangitis

(2016) Konstantinos N. Lazaridis et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pancreatic Autoantibodies Against CUZD1 and GP2 Are Associated with Distinct Clinical Phenotypes of Crohnʼs Disease

(2015) Maike Anna Michaels et al.   INFLAMMATORY BOWEL DISEASES

Rediscovery of the Anti-Pancreatic Antibodies and Evaluation of their Prognostic Value in a Prospective Clinical Cohort of Crohn’s Patients: The Importance of Specific Target Antigens [GP2 and CUZD1]

(2015) Maria Papp et al.   Journal of Crohns & Colitis

Serological studies in inflammatory bowel disease

(2014) Maria Papp et al.   CURRENT OPINION IN GASTROENTEROLOGY

Species-specific and pathotype-specific binding of bacteria to zymogen granule membrane glycoprotein 2 (GP2)

(2014) Peter Schierack et al.   GUT

Prognosis of Primary Sclerosing Cholangitis in Israel is Independent of Coexisting Inflammatory Bowel Disease

(2014) H. Yanai et al.   Journal of Crohns & Colitis

Cutting Edge: FimH Adhesin of Type 1 Fimbriae Is a Novel TLR4 Ligand

(2014) K. L. Mossman et al.   JOURNAL OF IMMUNOLOGY

Population-based epidemiology, malignancy risk, and outcome of primary sclerosing cholangitis

(2013) Kirsten Boonstra et al.   HEPATOLOGY

High prevalence of IgA class anti-neutrophil cytoplasmic antibodies (ANCA) is associated with increased risk of bacterial infection in patients with cirrhosis

(2013) Maria Papp et al.   JOURNAL OF HEPATOLOGY

Point Mutations in FimH Adhesin of Crohn's Disease-Associated Adherent-Invasive Escherichia coli Enhance Intestinal Inflammatory Response

(2013) Nicolas Dreux et al.   PLoS Pathogens

Autoantibodies against exocrine pancreas in Crohn's disease are directed against two antigens: The glycoproteins CUZD1 and GP2

(2012) Lars Komorowski et al.   Journal of Crohns & Colitis

Pathogenesis of primary sclerosing cholangitis

(2011) Marion J. Pollheimer et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut

(2011) N J Mantis et al.   Mucosal Immunology

Type I interferons: crucial participants in disease amplification in autoimmunity

(2010) John C. Hall et al.   Nature Reviews Rheumatology

Presence of Anti-Microbial Antibodies in Liver Cirrhosis – A Tell-Tale Sign of Compromised Immunity?

(2010) Maria Papp et al.   PLoS One

Evaluation of the Combined Application of Ethanol-Fixed and Formaldehyde-Fixed Neutrophil Substrates for Identifying Atypical Perinuclear Antineutrophil Cytoplasmic Antibodies in Inflammatory Bowel Disease

(2009) M. Papp et al.   Clinical and Vaccine Immunology

Identification of GP2, the major zymogen granule membrane glycoprotein, as the autoantigen of pancreatic antibodies in Crohn's disease

(2009) D. Roggenbuck et al.   GUT

p-ANCAs in autoimmune liver disorders recognise human  -tubulin isotype 5 and cross-react with microbial protein FtsZ

(2009) B. Terjung et al.   GUT

Antigen Binding to Secretory Immunoglobulin A Results in Decreased Sensitivity to Intestinal Proteases and Increased Binding to Cellular Fc Receptors

(2009) Mélanie Duc et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uptake through glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response

(2009) Koji Hase et al.   NATURE