Structural properties of apolipoprotein A-I mimetic peptides that promote ABCA1-dependent cholesterol efflux

Amphipathic polyproline peptides stimulate cholesterol efflux by the ABCA1 transporter

(2016) D.O. Sviridov et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

High-Density Lipoprotein Infusion Therapy and Atherosclerosis

(2016) Nan Chen et al.   Cardiology in Review

Enhanced HDL Functionality in Small HDL Species Produced Upon Remodeling of HDL by Reconstituted HDL, CSL112Novelty and Significance

(2016) Svetlana A. Didichenko et al.   CIRCULATION RESEARCH

The effect of phospholipid composition of reconstituted HDL on its cholesterol efflux and anti-inflammatory properties

(2015) Anna Schwendeman et al.   JOURNAL OF LIPID RESEARCH

Surface Density-Induced Pleating of a Lipid Monolayer Drives Nascent High-Density Lipoprotein Assembly

(2015) Jere P. Segrest et al.   STRUCTURE

Infusion of Reconstituted High‐Density Lipoprotein, CSL112, in Patients With Atherosclerosis: Safety and Pharmacokinetic Results From a Phase 2a Randomized Clinical Trial

(2015) Pierluigi Tricoci et al.   Journal of the American Heart Association

CSL112 Enhances Biomarkers of Reverse Cholesterol Transport After Single and Multiple Infusions in Healthy Subjects

(2014) Andreas Gille et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Effects of the high-density lipoprotein mimetic agent CER-001 on coronary atherosclerosis in patients with acute coronary syndromes: a randomized trial

(2014) J.-C. Tardif et al.   EUROPEAN HEART JOURNAL

Molecular Mechanisms of Cellular Cholesterol Efflux

(2014) Michael C. Phillips   JOURNAL OF BIOLOGICAL CHEMISTRY

Accurate and efficient integration for molecular dynamics simulations at constant temperature and pressure

(2013) Ross A. Lippert et al.   JOURNAL OF CHEMICAL PHYSICS

A multiple ascending dose study of CSL112, an infused formulation of ApoA-I

(2013) Rachael Easton et al.   JOURNAL OF CLINICAL PHARMACOLOGY

HDL and cholesterol: life after the divorce?

(2013) Kasey C. Vickers et al.   JOURNAL OF LIPID RESEARCH

Simulations of Anionic Lipid Membranes: Development of Interaction-Specific Ion Parameters and Validation Using NMR Data

(2013) Richard M. Venable et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles

(2012) Robert B. Best et al.   Journal of Chemical Theory and Computation

Helix stabilization of amphipathic peptides by hydrocarbon stapling increases cholesterol efflux by the ABCA1 transporter

(2011) D.O. Sviridov et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A sensitive assay for ABCA1-mediated cholesterol efflux using BODIPY-cholesterol

(2011) Sandhya Sankaranarayanan et al.   JOURNAL OF LIPID RESEARCH

Structure/Function Relationships of Apolipoprotein A-I Mimetic Peptides

(2010) Wilissa D'Souza et al.   CIRCULATION RESEARCH

High-density lipoprotein heterogeneity and function in reverse cholesterol transport

(2010) George H Rothblat et al.   CURRENT OPINION IN LIPIDOLOGY

A new HDL mimetic peptide that stimulates cellular cholesterol efflux with high efficiency greatly reduces atherosclerosis in mice

(2010) John K. Bielicki et al.   JOURNAL OF LIPID RESEARCH

Treatment of patients with cardiovascular disease with L-4F, an apo-A1 mimetic, did not improve select biomarkers of HDL function

(2010) Catherine E. Watson et al.   JOURNAL OF LIPID RESEARCH

5A Apolipoprotein Mimetic Peptide Promotes Cholesterol Efflux and Reduces Atherosclerosis in Mice

(2010) M. J. A. Amar et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Trifluoroethanol-induced conformational transitions of proteins: Insights gained from the differences between α-lactalbumin and ribonuclease A

(2010) Klaus Gast et al.   PROTEIN SCIENCE

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Simulation of Osmotic Pressure in Concentrated Aqueous Salt Solutions

(2009) Yun Luo et al.   Journal of Physical Chemistry Letters

Reconstituted High-Density Lipoprotein Increases Plasma High-Density Lipoprotein Anti-Inflammatory Properties and Cholesterol Efflux Capacity in Patients With Type 2 Diabetes

(2009) Sanjay Patel et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

MPEx: A tool for exploring membrane proteins

(2009) Craig Snider et al.   PROTEIN SCIENCE

HELIQUEST: a web server to screen sequences with specific  -helical properties

(2008) R. Gautier et al.   BIOINFORMATICS

Asymmetry in the Lipid Affinity of Bihelical Amphipathic Peptides

(2008) Amar A. Sethi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CHARMM-GUI: A web-based graphical user interface for CHARMM

(2008) Sunhwan Jo et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Safety, pharmacokinetics, and pharmacodynamics of oral apoA-I mimetic peptide D-4F in high-risk cardiovascular patients

(2008) LeAnne T. Bloedon et al.   JOURNAL OF LIPID RESEARCH

Control of Ion Selectivity in LeuT: Two Na+ Binding Sites with Two Different Mechanisms

(2008) Sergei Y. Noskov et al.   JOURNAL OF MOLECULAR BIOLOGY