CFTR Deletion Confers Mitochondrial Dysfunction and Disrupts Lipid Homeostasis in Intestinal Epithelial Cells

Nuclear factor E2-related factor 2 deficiency impairs atherosclerotic lesion development but promotes features of plaque instability in hypercholesterolaemic mice

(2018) Anna-Kaisa Ruotsalainen et al.   CARDIOVASCULAR RESEARCH

Apple peel polyphenols reduce mitochondrial dysfunction in mice with DSS-induced ulcerative colitis

(2018) Pantea Rahmani Yeganeh et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Insight from mitochondrial functions and proteomics to understand cardiometabolic disorders in survivors of acute lymphoblastic leukemia

(2018) Jade Leahy et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Dietary intake and lipid profile in children and adolescents with cystic fibrosis

(2017) Janna W. Woestenenk et al.   Journal of Cystic Fibrosis

Lipid and lipoprotein abnormalities in acute lymphoblastic leukemia survivors

(2017) Sophia Morel et al.   JOURNAL OF LIPID RESEARCH

Apple peel polyphenols: a key player in the prevention and treatment of experimental inflammatory bowel disease

(2016) M.-C. Denis et al.   CLINICAL SCIENCE

Regulation of endothelial dynamics by PGC-1α relies on ROS control of VEGF-A signaling

(2016) Nieves García-Quintans et al.   FREE RADICAL BIOLOGY AND MEDICINE

Targeted CFTR gene disruption with zinc-finger nucleases in human intestinal epithelial cells induces oxidative stress and inflammation

(2016) Marie-Laure Kleme et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Characterization of mitochondrial function in cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function

(2016) Anna Atlante et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Cystic Fibrosis-Related Oxidative Stress and Intestinal Lipid Disorders

(2015) Marie-Laure Kleme et al.   ANTIOXIDANTS & REDOX SIGNALING

The emerging role of Nrf2 in mitochondrial function

(2015) Albena T. Dinkova-Kostova et al.   FREE RADICAL BIOLOGY AND MEDICINE

AMPK in the Small Intestine in Normal and Pathophysiological Conditions

(2014) Elodie Harmel et al.   ENDOCRINOLOGY

Deficiency in Nrf2 transcription factor decreases adipose tissue mass and hepatic lipid accumulation in leptin-deficient mice

(2014) Jialin Xu et al.   Obesity

Correction: CFTR Depletion Results in Changes in Fatty Acid Composition and Promotes Lipogenesis in Intestinal Caco 2/15 Cells

(2014) Geneviève Mailhot et al.   PLoS One

PCSK9 plays a significant role in cholesterol homeostasis and lipid transport in intestinal epithelial cells

(2013) Emile Levy et al.   ATHEROSCLEROSIS

The absence of macrophage Nrf2 promotes early atherogenesis

(2013) Anna-Kaisa Ruotsalainen et al.   CARDIOVASCULAR RESEARCH

The Cystic Fibrosis Intestine

(2013) R. C. De Lisle et al.   Cold Spring Harbor Perspectives in Medicine

CFTR activity and mitochondrial function

(2013) Angel Gabriel Valdivieso et al.   Redox Biology

Antioxidative properties of paraoxonase 2 in intestinal epithelial cells

(2012) Louis-Philippe Précourt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Interaction with CREB binding protein modulates the activities of Nrf2 and NF-κB in cystic fibrosis airway epithelial cells

(2012) Assem G. Ziady et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Myeloid Deletion of Nuclear Factor Erythroid 2−Related Factor 2 Increases Atherosclerosis and Liver Injury

(2012) Alan R. Collins et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Increased arterial stiffness in children with cystic fibrosis: Table 1–

(2012) Tobias Buehler et al.   EUROPEAN RESPIRATORY JOURNAL

Nrf2 in bone marrow-derived cells positively contributes to the advanced stage of atherosclerotic plaque formation

(2012) Nobuhiko Harada et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hypertriglyceridemia is associated with insulin levels in adult cystic fibrosis patients

(2012) Marie-Claire Ishimo et al.   Journal of Cystic Fibrosis

Transcriptional integration of mitochondrial biogenesis

(2012) Richard C. Scarpulla et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Oxidative stress and antioxidant therapy in cystic fibrosis

(2011) Francesco Galli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

DHA and EPA reverse cystic fibrosis-related FA abnormalities by suppressing FA desaturase expression and activity

(2011) Sarah W. Njoroge et al.   JOURNAL OF LIPID RESEARCH

Vasoactive intestinal peptide reduces oxidative stress in pancreatic acinar cells through the inhibition of NADPH oxidase

(2011) Nao Fujimori et al.   PEPTIDES

Pathology of Gastrointestinal Organs in a Porcine Model of Cystic Fibrosis

(2010) David K. Meyerholz et al.   AMERICAN JOURNAL OF PATHOLOGY

Impaired Redox Signaling and Antioxidant Gene Expression in Endothelial Cells in Diabetes: A Role for Mitochondria and the Nuclear Factor-E2-Related Factor 2-Kelch-Like ECH-Associated Protein 1 Defense Pathway

(2010) Xinghua Cheng et al.   ANTIOXIDANTS & REDOX SIGNALING

Total Skeletal Muscle PGC-1 Deficiency Uncouples Mitochondrial Derangements from Fiber Type Determination and Insulin Sensitivity

(2010) Christoph Zechner et al.   Cell Metabolism

Therapeutic implications of oxidative stress in acute and chronic pancreatitis

(2010) Maxim S Petrov   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Oxidative Stress and Mitochondrial Functions in the Intestinal Caco-2/15 Cell Line

(2010) Rame Taha et al.   PLoS One

Fatty acid metabolism in cystic fibrosis

(2010) Birgitta Strandvik   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

CFTR knockdown stimulates lipid synthesis and transport in intestinal Caco-2/15 cells

(2009) Geneviève Mailhot et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

cAMP-mediated regulation of cholesterol accumulation in cystic fibrosis and Niemann-Pick type C cells

(2008) Mary E. Manson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Intestinal fatty acid binding protein regulates mitochondrion β-oxidation and cholesterol uptake

(2008) Alain Montoudis et al.   JOURNAL OF LIPID RESEARCH

Disruption of Nrf2, a Key Inducer of Antioxidant Defenses, Attenuates ApoE-Mediated Atherosclerosis in Mice

(2008) Thomas E. Sussan et al.   PLoS One