Review
Immunology
Jiahui Yan, Sisi Yang, Liang Han, Xin Ba, Pan Shen, Weiji Lin, Tingting Li, Ruiyuan Zhang, Ying Huang, Yao Huang, Kai Qin, Yu Wang, Shenghao Tu, Zhe Chen
Summary: This article describes the unique lipid profile of RA, explores the mechanisms underlying lipid changes, and investigates the impact of lipid changes on cardiovascular disease.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Multidisciplinary Sciences
Ian Kwong Yun Phoon, Yi Ling Eileen Koh, Xiaoxuan Guo, Sankari Usha, Ngiap Chuan Tan
Summary: Recent research in Singapore compared fasting and non-fasting lipid profiles in Asian patients with type-2 diabetes mellitus and dyslipidaemia. The study found that the non-fasting lipid profile was similar to the fasting profile in patients taking statin medication, suggesting that non-fasting lipid profiles can be used to assess cholesterol treatment status in this population.
SCIENTIFIC REPORTS
(2021)
Article
Endocrinology & Metabolism
Arthur Eumann Mesas, Miriam Garrido-Miguel, Ruben Fernandez-Rodriguez, Sofia Fernandez Franco, Cristina Lugones-Sanchez, Luis Garcia-Ortiz, Vicente Martinez-Vizcaino
Summary: This study examined the relationship between egg consumption and blood lipid parameters and found that higher egg consumption was not associated with total cholesterol, HDL cholesterol, and triglyceride levels, but was associated with lower LDL cholesterol levels and LDL/HDL ratio. In individuals with chronic metabolic disorders, higher egg consumption was not associated with lipid abnormalities, while in individuals without these conditions, those who consumed more eggs had better lipid profiles.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Review
Medicine, General & Internal
Jeffrey E. Jones, Kevin S. Tang, Ailin Barseghian, Nathan D. Wong
Summary: Discussions on the exact targets for LDL-C reduction have become more aggressive, especially for high-risk patients with ASCVD. Statin therapy has been proven effective, and recent trials have shown the impact of non-statin therapies as well.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Nutrition & Dietetics
Rebeca Quiros-Fernandez, Bricia Lopez-Plaza, Laura M. Bermejo, Samara Palma Milla, Andrea Zangara, Carmen Gomez Candela
Summary: The supplement containing HT and PC showed significant improvement in dyslipidemia, indicating its potential for preventing atherosclerosis and protecting the heart in adults.
Review
Endocrinology & Metabolism
Parham Mardi, Fatemeh Abdi, Amir Ehsani, Ehsan Seif, Shirin Djalalinia, Javad Heshmati, Ehsan Shahrestanaki, Armita Mahdavi Gorabi, Mostafa Qorbani
Summary: This study examined the association between novel atherogenic lipid indices (including non-HDL-C, atherogenic index, and the difference between non-HDL-C and LDL-C) and metabolic syndrome (MetS) or its components. The results showed a strong correlation between these indices and increased odds of MetS and its components.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Clinical Neurology
Weijian Li, Zegui Huang, Wei Fang, Xianxuan Wang, Zefeng Cai, Guanzhi Chen, Weiqiang Wu, Zhichao Chen, Shouling Wu, Youren Chen
Summary: Studies have found a correlation between remnant cholesterol and the risk of ischemic stroke. This study aimed to investigate the impact of visit-to-visit variability in remnant cholesterol concentration on the development of ischemic stroke in the general population. The results showed that greater remnant cholesterol variability was associated with a higher risk of ischemic stroke.
Article
Multidisciplinary Sciences
Mogomotsi Dintshi, Ngalulawa Kone, Siyabonga Khoza
Summary: This study compared the calculated LDL-C using the Friedewald and Martin-Hopkins formulae to the measured LDL-C. The results showed that the Martin-Hopkins formula performed better at LDL-C treatment target <1.4 mmol/L and had lower positive bias in patients with hypertriglyceridemia.
Article
Multidisciplinary Sciences
C. J. MacDonald, A. L. Madika, G. Severi, A. Fournier, M. C. Boutron-Ruault
Summary: The study found that non-O blood groups, particularly the A group, are associated with an increased risk of dyslipidaemia. Current smokers have a 30% higher risk of dyslipidaemia compared to never-smokers. These results could be useful for personalized approaches to preventing cardiovascular risk factors.
SCIENTIFIC REPORTS
(2021)
Article
Urology & Nephrology
Arata Osanami, Marenao Tanaka, Masato Furuhashi, Hirofumi Ohnishi, Nagisa Hanawa, Tomohisa Yamashita, Norihito Moniwa, Tetsuji Miura
Summary: This study examines the relationship between serum lipid levels and the time course of renal function in a cohort of healthy subjects. The findings suggest that a high LDL-C level may be a risk factor for new-onset chronic kidney disease in apparently healthy males.
CLINICAL KIDNEY JOURNAL
(2022)
Article
Pharmacology & Pharmacy
Elena Osto, Fabrizia Bonacina, Angela Pirillo, Giuseppe Danilo Norata
Summary: SGLT2i is an effective and safe glucose-lowering medication for patients with type 2 diabetes, providing protection against heart and kidney failure. However, the impact of SGLT2i on lipid profiles and atherosclerotic cardiovascular risk requires further investigation.
PHARMACOLOGICAL RESEARCH
(2023)
Review
Cardiac & Cardiovascular Systems
Michael J. Wilkinson, Norman E. Lepor, Erin D. Michos
Summary: Management of elevated low-density lipoprotein cholesterol (LDL-C) is crucial for preventing atherosclerotic cardiovascular disease (ASCVD) and reducing ASCVD events. Statins are recommended as the first-line therapy for LDL-C reduction, while nonstatin lipid-lowering therapy can be added for intensive LDL-C lowering in high-risk patients. However, many high-risk patients fail to meet LDL-C thresholds despite guideline recommendations. This review explores the challenges of LDL-C lowering and proposes a new approach to ASCVD risk assessment and treatment.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Medicine, General & Internal
Jamal S. Rana, Salim S. Virani, Howard H. Moffet, Jennifer Y. Liu, Landis A. Coghlan, Jitesh Vasadia, Christie M. Ballantyne, Andrew J. Karter
Summary: The study aimed to evaluate the association between outpatient LDL-C testing and subsequent statin adherence and intensification in patients after an ASCVD event. The results showed that LDL-C testing was associated with improved statin adherence and higher rates of treatment intensification.
AMERICAN JOURNAL OF MEDICINE
(2022)
Article
Clinical Neurology
Xiaoling Zhang, Tong Tong, Andrew Chang, Ting Fang Alvin Ang, Qiushan Tao, Sanford Auerbach, Sherral Devine, Wei Qiao Qiu, Jesse Mez, Joseph Massaro, Kathryn L. Lunetta, Rhoda Au, Lindsay A. Farrer
Summary: This study found that an increase in high density lipoprotein (HDL) cholesterol levels was associated with a decreased risk of Alzheimer's disease (AD) in early and middle adulthood, while an increase in glucose levels in middle adulthood was associated with an increased risk of AD. These findings suggest that managing cholesterol and glucose from early adulthood can lower the risk of AD.
ALZHEIMERS & DEMENTIA
(2023)
Article
Multidisciplinary Sciences
Faezeh Abaj, Fariba Koohdani
Summary: This study aimed to investigate the impact of dietary intakes on the relationship between ApoB EcoRI gene and lipid profile, as well as serum inflammatory markers, in patients with type 2 diabetes. The results showed that patients with the AA or AG genotype were more responsive to increased dietary fat, carbohydrate, protein intake, with higher levels of plasma lipid markers. Additionally, the correlation between ApoB EcoRI and metabolic markers was attenuated with higher monounsaturated fatty acid consumption.
SCIENTIFIC REPORTS
(2022)
Editorial Material
Nutrition & Dietetics
Shweta Khandelwal, Usha Ramakrishnan
JOURNAL OF NUTRITION
(2019)
Article
Nutrition & Dietetics
Shweta Khandelwal, Dimple Kondal, Monica Chaudhry, Kamal Patil, Mallaiah Kenchaveeraiah Swamy, Deepa Metgud, Sandesh Jogalekar, Mahesh Kamate, Gauri Divan, Ruby Gupta, Dorairaj Prabhakaran, Nikhil Tandon, Usha Ramakrishnan, Aryeh D. Stein
Article
Nutrition & Dietetics
Shweta Khandelwal, Dimple Kondal, Monica Chaudhry, Kamal Patil, Mallaiah Kenchaveeraiah Swamy, Gangubai Pujeri, Swati Babu Mane, Yashaswi Kudachi, Ruby Gupta, Usha Ramakrishnan, Aryeh D. Stein, Dorairaj Prabhakaran, Nikhil Tandon
Summary: This study conducted in India examined the impact of supplementing pregnant women with 400 mg/day of algal DHA on newborn anthropometry and gestational duration. The results showed that there were no significant differences in birth weight, length, or head circumference of offspring between the group supplemented with DHA and the placebo group.
Article
Nutrition & Dietetics
Rajesh Kumar Rai, Sandhya S. Kumar, Devraj J. Parasannanavar, Shweta Khandelwal, Hemalatha Rajkumar
Summary: The provision of nutrition supplements to pregnant mothers through Anganwadi centres in India is associated with a decreased risk of low birth weight and neonatal mortality, but may not be effective in preventing extremely low birth weight.
BRITISH JOURNAL OF NUTRITION
(2022)
Article
Medicine, General & Internal
Himanshu Pandya, Thomas Chacko, Ciraj Ali Mohammed
Summary: The replacement of MCI with NMC aimed to improve regulatory procedures and medical education quality in India. Global collaborative efforts have focused on promoting accreditation through WFME recognition programme, establishing expert consensus standards, and Guidelines for Accreditation of Basic Medical Education. Many medical schools and regulatory agencies have adopted WFME standards and achieved recognition. However, gaps exist between the intent of NMC Act and MSRs notification, and a regulatory model is recommended to align with NMC's goals and gain international recognition for medical schools in India.
NATIONAL MEDICAL JOURNAL OF INDIA
(2021)
Article
Environmental Sciences
Shweta Khandelwal, Dimple Kondal, Anindita Ray Chakravarti, Soumam Dutta, Bipsa Banerjee, Monica Chaudhry, Kamal Patil, Mallaiah Kenchaveeraiah Swamy, Usha Ramakrishnan, Dorairaj Prabhakaran, Nikhil Tandon, Aryeh D. Stein
Summary: Poor infant young child feeding (IYCF) practices can lead to malnutrition, poor psychosocial development, poor school performance, and lower productivity in later life, perpetuating a vicious cycle. This study examined IYCF practices in a maternal-child birth cohort in Belagavi, Karnataka, India. The findings showed that only 77.9% of infants were breastfed within 1 hour of delivery, and 52.4% were exclusively breastfed at 6 months. At 12 months, while most infants were breastfed (90%), 39% also received formula. Although a majority of infants met the minimum meal frequency (94.4%), only 55% had a minimum acceptable diet. The mean dietary diversity score was 4.7 +/- 1.1. Furthermore, a large proportion of infants did not consume vegetables and/or fruits until 12 months of age (33.8%). The consumption of ultra-processed foods high in trans-fats, sugars, and salt was high (85.8%). Therefore, there is an urgent need for high-quality, sustainable, and scalable interventions to improve IYCF practices and enhance diet diversity and overall nutritional intake among young children in low- and middle-income group settings.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Nutrition & Dietetics
Zeyuan Wang, Monica Chaudhry, Ritesh Mistry, Belinda L. Needham, Ana Baylin, Peter Mancuso, Kalpana Singh, Shweta Khandelwal
Summary: This mixed-method study examines the food/nutrient intake among early postpartum women in Belgaum, India using questionnaires, dietary recalls, and qualitative interviews. The results indicate that the intake of energy, protein, and most micronutrients was significantly lower than the Recommended Dietary Allowance, and many mothers restricted their consumption of certain foods due to their perceptions of food and health beliefs.
ECOLOGY OF FOOD AND NUTRITION
(2022)
Review
Environmental Sciences
Shweta Khandelwal, Mahima Mehra, Ayushi Singh
Summary: This paper assesses the impact of COVID-19 pandemic-related pathways on the first thousand days of life in India, revealing varied challenges in social security, food insecurity, service delivery, and maternal and child nutrition in different regions and economic conditions. The study highlights the need for more comprehensive research on the impact of the COVID-19 pandemic on the first 1000 days of life in India and globally.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Letter
Psychiatry
Jagdish Varma, Tejas Patel, Anusha Prabhakaran, Jaikumar Contractor, Ankur Mahida, Utpala Kharod, Himanshu Pandya
ANNALS OF INDIAN PSYCHIATRY
(2023)
Review
Medicine, General & Internal
Dinesh Kumar, Jagdish Varma, Amol Dongre, Himanshu Pandya
Summary: This scoping review explored the focus of initiatives from medical educators in India during the Covid-19 pandemic. The majority of studies evaluated conceptual understanding among undergraduate medical students, with a particular emphasis on students' and faculty's perspectives on online learning.
NATIONAL MEDICAL JOURNAL OF INDIA
(2022)
Article
Primary Health Care
Radhika H. Pandya, Mayur Kiran Shinde, Viral B. Patel, Ajay Gajanan Phatak, Himanshu Pandya
Summary: This study aimed to optimize the chest CT scanning protocol for reducing radiation dose in patients with COVID-19 infection. The results showed that the optimized protocol was clinically feasible and dose optimization could be achieved through a simple educational intervention.
JOURNAL OF FAMILY MEDICINE AND PRIMARY CARE
(2022)
Letter
Clinical Neurology
Jalpan Patel, Ishani Patel, Devangi Desai, Soaham Desai, Himanshu Pandya
ANNALS OF INDIAN ACADEMY OF NEUROLOGY
(2021)
Article
Public, Environmental & Occupational Health
Shweta Khandelwal, Garima Verma, Nida I. Shaikh, Karen R. Siegel, Divya Soni, Deepa Soni, Anne-Marie Thow
JOURNAL OF HUNGER & ENVIRONMENTAL NUTRITION
(2020)
Article
Nutrition & Dietetics
Krithiga Shridhar, Sanjay Kinra, Ruby Gupta, Shweta Khandelwal, D. Prabhakaran, Sharon E. Cox, Preet K. Dhillon
CURRENT DEVELOPMENTS IN NUTRITION
(2019)