Article
Neuroimaging
Zachary Anderson, Katherine S. F. Damme, Ann L. Carroll, Iris Ka-Yi Chat, Katherine S. Young, Michelle G. Craske, Susan Bookheimer, Richard Zinbarg, Robin Nusslock
Summary: Depression and anxiety are associated with abnormalities in brain regions involved in reward processing. The tri-level model provides more precision in understanding the subtle neural changes associated with depression and anxiety symptoms. The study found that heightened General Distress was associated with lower connectivity between the ventral striatum and medial orbitofrontal cortex during reward anticipation and reward outcome. Heightened Anhedonia-Apprehension was associated with greater connectivity between the ventral striatum and amygdala during reward anticipation. These findings have important implications for understanding the pathophysiology of mood and anxiety symptoms.
NEUROIMAGE-CLINICAL
(2023)
Review
Behavioral Sciences
Eduardo Duarte-Silva, Alice Chevrollier Oria, Ingrid Prata Mendonca, Michel Gomes de Melo, Igor Henrique R. Paiva, Michael Maes, Samia R. L. Joca, Christina Alves Peixoto
Summary: Extracellular Vesicles (EVs) are small vesicles used by cells to communicate with each other and can change the function and state of cells. EVs have been implicated in the development and progression of various diseases, and understanding their roles is crucial for treatment and early diagnosis.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Article
Medicine, General & Internal
Na Wu, Xiangmei Kong, Xinghuai Sun
Summary: Anxiety and depression are common in Chinese patients with glaucoma. The self-reported VR-QoL is beneficial in assessing the psychological status of patients, while objective visual function indices provide little indication of it.
Article
Medicine, General & Internal
Yuanyuan Wang, Jens H. Bos, Catharina C. M. Schuiling-Veninga, H. Marike Boezen, Job F. M. van Boven, Bob Wilffert, Eelko Hak
Summary: The study found that there was a lower incidence of NPAEs among general population using varenicline compared to nicotine replacement therapy, while there was no significant difference in NPAEs incidence between COPD patients using varenicline and NRT.
Article
Medicine, General & Internal
Mafalda Simoes Cunha, Rita Amaral, Ana Margarida Pereira, Rute Almeida, Magna Alves-Correia, Claudia Chaves Loureiro, Cristina Lopes, Joana Carvalho, Carmelita Ribeiro, Carmen Vidal, Dario Antolin-Amerigo, Diana Pinto, Manuel Ferreira-Magalhaes, Maria Joao Vasconcelos, Carlos Lozoya, Natacha Santos, Francisca Cardia, Luis Taborda-Barata, Rosario Ferreira, Pedro Morais Silva, Tania Monteiro Ferreira, Raquel Camara, Eurico Silva, Diana Bordalo, Cristina Guimaraes, Maria Jose Calix, Sofia da Silva, Maria Luis Marques, Ana Morete, Carlos Nunes, Claudia Vieira, Rosalia Pascoa, Adelaide Alves, Jose Varanda Marques, Bruno Reis, Luis Monteiro, Rosario Monteiro, Margarida Cepa, Bruno Valentim, Daniela Sousa Coelho, Sara Fernandes, Patricia Meireles, Margarida Abreu Aguiar, Ana Rita Mourao, Joao A. Fonseca, Cristina Jacome
Summary: This study investigated the frequency of anxiety and depression in patients with persistent asthma and found that at least 1/3 of the patients experience symptoms of anxiety and depression, highlighting the importance of screening for these disorders in asthma patients. The HADS and EQ-5D questionnaires showed moderate agreement in identifying anxiety and depression symptoms.
Review
Medicine, General & Internal
Keyi Zhou, Jiarui Chen, Chongmei Huang, Siyuan Tang
Summary: This systematic review aims to summarize the current evidence of the prevalence of and factors influencing depression and anxiety among Chinese adolescents. The researchers will conduct a comprehensive search of English and Chinese databases to identify eligible studies and extract data. The results will be published in a peer-reviewed journal or disseminated at relevant conferences.
Article
Medicine, General & Internal
Chenbing Sun, Shuliu Sang, Yunzhe Tang, Xiaodie Niu, Hwa-Seung Yoo, Ping Zhou, Hao Liu, Yabin Gong, Ling Xu
Summary: This study aims to evaluate the effects of music therapy on anxiety and cytokine levels in cancer patients. A total of 60 patients with malignant tumors will be randomly assigned to either a music therapy group or a non-music therapy group. The primary outcomes include anxiety scores and cytokine levels. The findings of this study will be published and presented at conferences.
Article
Medicine, General & Internal
Deborah Xin Yi Chung, Ying Ern Loo, Yu Heng Kwan, Jie Kie Phang, Ting Hui Woon, Wei Rui Goh, Stanley Angkodjojo, Warren Fong
Summary: This study examined the association between anxiety, depression, and resilience with overall health and functioning in axial spondyloarthritis (axSpA) patients. The results showed that anxiety and depression were associated with poorer health and functioning, while resilience was not.
Review
Clinical Neurology
Katrina N. Kidd, Divya Prasad, Jasmyn E. A. Cunningham, Taiane de Azevedo Cardoso, Benicio N. Frey
Summary: This study found that poor-quality parent-child relationships may increase the risk of mood and anxiety disorders in adulthood. Individuals with major depression, panic disorder, or persistent depressive disorder reported lower parental care and higher overprotection. Those with mood or anxiety disorders tended to report higher parental abuse.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Jimin Lee, Byung-Soo Kim, Jin Pyo Hong, Seong-Jin Cho, Jun-Young Lee, Jong-Ik Park, Hong Jin Jeon, Sung Man Chang
Summary: Despite the high prevalence of alcohol use disorders (AUDs) in Korea, few studies have been conducted on the temporal priority with comorbid mental disorders. We investigated the temporal priority of lifetime AUDs and comorbid mood and anxiety disorders among the general population of Korea. The results showed that mood and anxiety disorders are more likely to occur before alcohol dependence, while specific phobia is more likely to occur before alcohol abuse.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychology, Multidisciplinary
Hui Shi, Honglin Ren, Ying Tian, Zhe Chen, Cuiping Xu, Lu Lu, Xiaoyu Ma, Xiaoyan Li, Wenming Chen, Tong Guo, Cuizhen Fan, Wen Gao
Summary: The study investigated the prevalence of depression or anxiety in patients with multiple myeloma during maintenance treatment in China. Results showed that despite being in clinical remission, depressive mood problems in patients with MM remain prominent. Clinicians should enhance mood assessment and management in patients with concomitant pain.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Psychology, Multidisciplinary
Alicia Remartinez-Hamed, Maria Angeles Perez-Morente, Maria Adelaida Alvarez-Serrano, Encarnacion Martinez-Garcia, Alberto Gonzalez-Garcia, Inmaculada Garcia-Garcia, Adelina Martin-Salvador
Summary: Pregnancy and/or the puerperium increase the vulnerability of women to mental disorders, especially anxiety and depression, and this risk is further heightened during stressful contexts such as the COVID-19 pandemic. A study conducted in Melilla, a Spanish cross-border city with Morocco, found a high risk of postpartum depression (85.5%) and anxiety (63.8%), with severe anxiety affecting 40.6% of cases. Predictors of postpartum depression included a personal history of mood disorders and a COVID-19 diagnosis during pregnancy or postpartum. Factors predicting anxiety included mood antecedents, a COVID-19 diagnosis during pregnancy or postpartum, and being a multipara. Special attention should be given to women with a history of mood disorders and a positive COVID-19 diagnosis during pregnancy or postpartum, particularly multiparous women, due to their impact on postpartum mental health.
CURRENT PSYCHOLOGY
(2023)
Article
Medicine, General & Internal
Asamnew Teklewold Gebremariam, Abenet Menene Gurara, Teresa Kisi Beyen
Summary: This study assessed the magnitude of depression, anxiety, and psychological distress in a secondary and preparatory school in Ethiopia. The results revealed high levels of these mental health issues, with depression linked to positive relationships with classmates, anxiety associated with alcohol consumption, and educational level related to psychological distress.
Review
Medicine, General & Internal
Nurbanu Somani, Eldre Beukes, Alexander Street, Rosie Lindsay, Peter M. Allen
Summary: This scoping review aims to assess the therapeutic outcomes and strategies of music-based interventions for individuals with a vision impairment. The review will include studies that use music as a treatment intervention for all vision impairment populations and will conduct a narrative synthesis to compare therapeutic outcomes. The findings of this review will be important for guiding the development of future interventions or strategies using music to improve well-being in individuals with vision impairments.
Article
Medicine, General & Internal
Josh Hope-Bell, Jerry Draper-Rodi, Darren J. Edwards
Summary: This study aims to investigate the feasibility and acceptability of four osteopathic interventions for improving mental health outcomes. It will use a mixed-methods design, including quantitative and qualitative data collection and analysis. The results will inform the development of a future randomized controlled trial.
Review
Neurosciences
Andre Zugman, Anita Harrewijn, Elise M. Cardinale, Hannah Zwiebel, Gabrielle F. Freitag, Katy E. Werwath, Janna M. Bas-Hoogendam, Nynke A. Groenewold, Moji Aghajani, Kevin Hilbert, Narcis Cardoner, Daniel Porta-Casteras, Savannah Gosnell, Ramiro Salas, Karina S. Blair, James R. Blair, Mira Z. Hammoud, Mohammed Milad, Katie Burkhouse, K. Luan Phan, Heidi K. Schroeder, Jeffrey R. Strawn, Katja Beesdo-Baum, Sophia I. Thomopoulos, Hans J. Grabe, Sandra van der Auwera, Katharina Wittfeld, Jared A. Nielsen, Randy Buckner, Jordan W. Smoller, Benson Mwangi, Jair C. Soares, Mon-Ju Wu, Giovana B. Zunta-Soares, Andrea P. Jackowski, Pedro M. Pan, Giovanni A. Salum, Michal Assaf, Gretchen J. Diefenbach, Paolo Brambilla, Eleonora Maggioni, David Hofmann, Thomas Straube, Carmen Andreescu, Rachel Berta, Erica Tamburo, Rebecca Price, Gisele G. Manfro, Hugo D. Critchley, Elena Makovac, Matteo Mancini, Frances Meeten, Cristina Ottaviani, Federica Agosta, Elisa Canu, Camilla Cividini, Massimo Filippi, Milutin Kostic, Ana Munjiza, Courtney A. Filippi, Ellen Leibenluft, Bianca A. V. Alberton, Nicholas L. Balderston, Monique Ernst, Christian Grillon, Lilianne R. Mujica-Parodi, Helena van Nieuwenhuizen, Gregory A. Fonzo, Martin P. Paulus, Murray B. Stein, Raquel E. Gur, Ruben C. Gur, Antonia N. Kaczkurkin, Bart Larsen, Theodore D. Satterthwaite, Jennifer Harper, Michael Myers, Michael T. Perino, Qiongru Yu, Chad M. Sylvester, Dick J. Veltman, Ulrike Lueken, Nic J. A. van der Wee, Dan J. Stein, Neda Jahanshad, Paul M. Thompson, Daniel S. Pine, Anderson M. Winkler
Summary: The ENIGMA-Anxiety/GAD group is conducting a mega-analysis of brain structural scans for generalized anxiety disorder. This report summarizes the challenges faced and the approach taken to overcome them, aiming to guide other research groups working with large brain imaging data sets.
HUMAN BRAIN MAPPING
(2022)
Article
Pharmacology & Pharmacy
Jingyi Xu, Xing Qiu, Gary Yu, Maria Ly, Jun Yang, Rona M. Silva, Xun Zhang, Mang Yu, Yinong Wang, Bruce Hammock, Kent E. Pinkerton, Dewei Zhao
Summary: Exposure to tobacco smoke has been linked to osteonecrosis of the femoral head, with soluble epoxide hydrolase inhibitors potentially offering protective effects, particularly in hypertensive rats.
Editorial Material
Geriatrics & Gerontology
Carmen Andreescu
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
(2022)
Letter
Geriatrics & Gerontology
Robert van Voren, Carmen Andreescu
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
(2022)
Editorial Material
Psychology, Clinical
Thomas E. E. Kraynak, Carmen Andreescu
INTERNATIONAL PSYCHOGERIATRICS
(2022)
Article
Biochemistry & Molecular Biology
Helmet T. Karim, Howard J. Aizenstein, Akiko Mizuno, Maria Ly, Carmen Andreescu, Minjie Wu, Chang Hyung Hong, Hyun Woong Roh, Bumhee Park, Heirim Lee, Na-Rae Kim, Jin Wook Choi, Sang Won Seo, Seong Hye Choi, Eun-Joo Kim, Byeong C. Kim, Jae Youn Cheong, Eunyoung Lee, Dong-gi Lee, Yong Hyuk Cho, So Young Moon, Sang Joon Son
Summary: The study found that the pretrained brain age model could reliably estimate brain age and was associated with amyloid deposition and cognitive decline. Baseline brain age residual could predict future cognitive worsening, offering new possibilities for discriminating and tracking cognitive impairment in older adults.
MOLECULAR PSYCHIATRY
(2022)
Article
Psychiatry
Akiko Mizuno, Helmet Talib Karim, Jordyn Newmark, Faiha Khan, Matthew Joseph Rosenblatt, Alyssa M. Neppach, MaKayla Lowe, Howard Jay Aizenstein, Douglas S. Mennin, Carmen Andreescu
Summary: Psychotherapeutic approaches have limited effect on reducing worry severity in late-life anxiety. This study found that self-referential processing of worry contents and reappraisal styles were associated with psychological and physiological burden.
FRONTIERS IN PSYCHIATRY
(2022)
Editorial Material
Psychiatry
Carmen Andreescu, Eric Lenze, Helen Lavretsky
Summary: This Viewpoint discusses the updated US Preventive Services Task Force recommendations for anxiety screening in adults.
Article
Radiology, Nuclear Medicine & Medical Imaging
Joshua Ward, Maria Ly, Cyrus A. Raji
Article
Geriatrics & Gerontology
Neha Jain, Yueting Wang, Yingjin Zhang, Erin Jacobsen, Carmen Andreescu, Beth E. Snitz, Chung-Chou H. Chang, Mary Ganguli
Summary: This study investigated the relationship between anxiety and mild cognitive impairment (MCI) at the population level, and examined whether perceived stress mediated this relationship. The results confirmed bidirectional longitudinal associations between anxiety and MCI, with perceived stress playing a significant mediating role in both directions.
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
(2023)
Article
Clinical Neurology
Matthew R. Brier, Zhuocheng Li, Maria Ly, Helmet T. Karim, Leda Liang, Weixin Du, John E. McCarthy, Anne H. Cross, Tammie L. S. Benzinger, Robert T. Naismith, Salim Chahin
Summary: Brain age, quantified using machine learning applied to structural MRI, is a clinically relevant biomarker that correlates with and predicts increasing disability in patients with multiple sclerosis (MS).
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY
(2023)
Article
Biochemistry & Molecular Biology
James D. D. Wilson, Andrew R. R. Gerlach, Helmet T. T. Karim, Howard J. J. Aizenstein, Carmen Andreescu
Summary: Rapid eye movement (REM) sleep is an important brain state that plays a crucial role in sleep and learning. This study demonstrates a link between connectivity changes between REM periods and memory enhancement, which contributes to a better understanding of the neurobiological mechanisms underlying memory.
MOLECULAR PSYCHIATRY
(2023)
Meeting Abstract
Geriatrics & Gerontology
Saurab Faruque, Natalie Bick, Helmet Karim, Meryl Butters, Carmen Andreescu, Howard Aizenstein
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
(2023)
Meeting Abstract
Neurosciences
Andrew Gerlach, James Wilson, Helmet Karim, Howard Aizenstein, Carmen Andreescu
NEUROPSYCHOPHARMACOLOGY
(2022)
Meeting Abstract
Neurosciences
Helmet Karim, Ahmad Mayeli, Francesco Donati, Brian Coffman, Daniel M. Blumberger, Noah Philip, Mary Phillips, Carmen Andreescu, Rebecca Price, Fabio Ferrarelli
NEUROPSYCHOPHARMACOLOGY
(2022)