Article
Biochemistry & Molecular Biology
Enrique Cadenas, Helmut Sies
Summary: Lester Packer, an inspirational scientific leader, had a profound impact on researchers in the field of oxidants and antioxidants. This article highlights key aspects of his career, from his early years at Brooklyn College and Yale University to his influential role at the University of California, Berkeley. His concept of the Antioxidant Network and his ability to foster international collaborations made him a respected figure in the scientific community.
ANTIOXIDANTS & REDOX SIGNALING
(2023)
Article
Business
Leonardo Augusto de Vasconcelos Gomes, Ximena Alejandra Flechas, Ana Lucia Figueiredo Facin, Felipe Mendes Borini
Summary: The introduction of supply chain management (SCM) in the 1980s and 1990s was a breakthrough in the field of management. Similar to SCM, ecosystem management (EM) represents a potential breakthrough, but currently lacks a general framework. Through a systematic literature review, this study proposes a definition of ecosystem and identifies the goals, scope, and boundaries of EM.
TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE
(2021)
Biographical-Item
Engineering, Chemical
Juergen Caro
Summary: Jorg Karger is a pioneering researcher in the field of diffusion, with over 50 years of active research experience in nanoporous materials. He is recognized as the most productive author in the field, with 247 entries related to diffusion in the title. His high total local citation score also indicates the exceptional quality of his publications.
CHEMIE INGENIEUR TECHNIK
(2023)
Review
Geochemistry & Geophysics
Joseph A. MacGregor, Linette N. Boisvert, Brooke Medley, Alek A. Petty, Jeremy P. Harbeck, Robin E. Bell, J. Bryan Blair, Edward Blanchard-Wrigglesworth, Ellen M. Buckley, Michael S. Christoffersen, James R. Cochran, Beata M. Csatho, Eugenia L. De Marco, RoseAnne T. Dominguez, Mark A. Fahnestock, Sinead L. Farrell, S. Prasad Gogineni, Jamin S. Greenbaum, Christy M. Hansen, Michelle A. Hofton, John W. Holt, Kenneth C. Jezek, Lora S. Koenig, Nathan T. Kurtz, Ronald Kwok, Christopher F. Larsen, Carlton J. Leuschen, Caitlin D. Locke, Serdar S. Manizade, Seelye Martin, Thomas A. Neumann, Sophie M. J. Nowicki, John D. Paden, Jacqueline A. Richter-Menge, Eric J. Rignot, Fernando Rodriguez-Morales, Matthew R. Siegfried, Benjamin E. Smith, John G. Sonntag, Michael Studinger, Kirsty J. Tinto, Martin Truffer, Thomas P. Wagner, John E. Woods, Duncan A. Young, James K. Yungel
Summary: Operation IceBridge conducted by NASA over 13 years aimed to survey land and sea ice using airborne laser altimetry. With 968 science flights, OIB greatly improved our understanding of land ice and sea ice, leading to numerous unexpected discoveries and providing valuable data for future research on the cryosphere.
REVIEWS OF GEOPHYSICS
(2021)
Review
Plant Sciences
Jason D. Fridley, Xiaojuan Liu, Natalia Perez-Harguindeguy, F. Stuart Chapin III, Mick Crawley, Gerlinde De Deyn, Sandra Diaz, James B. Grace, Peter Grubb, Susan Harrison, Sandra Lavorel, Zhimin Liu, Simon Pierce, Bernhard Schmid, Carly Stevens, David A. Wardle, Mark Westoby
Summary: J.P. Grime's contribution to the study of plant ecology has been instrumental in establishing it as an internationally recognized field in relation to global environmental change. In an article in the Journal of Ecology, 14 senior plant ecologists from around the world highlight Grime's foundational role in plant functional ecology, including his ability to spark controversy, his unique approach to theory formulation through clever experiments and standardized trait measurements, and the continued impact of his work on ecological science and policy.
JOURNAL OF ECOLOGY
(2023)
Article
Engineering, Aerospace
Flaviane C. F. Venditti, Sean E. Marshall, Maxime Devogele, Luisa F. Zambrano-Marin, Anna McGilvray
Summary: Ground-based radar systems play a critical role in characterizing near-Earth objects (NEOs) and space debris. They are important for both planetary defense and space situational/ domain awareness (SSA/SDA), but there are different considerations for supporting each area. Planetary defense focuses on asteroids and comets in heliocentric orbit, while SSA is concerned with artificial objects orbiting Earth. This document explores the radar capabilities of the Arecibo telescope and discusses future concepts for both planetary defense and SSA.
Review
Biochemistry & Molecular Biology
Hina Agraval, Hong Wei Chu
Summary: Smoking is known to contribute to various respiratory diseases, but studying its mechanisms in human lungs has been challenging. The lung organoid culture system, as a sophisticated ex vivo model, shows promise in investigating the harmful and immunological effects of smoking on human lungs and guiding future research directions.
Review
Pharmacology & Pharmacy
Samaneh Zolghadri, Mohammad Beygi, Tasneem F. Mohammad, Mahdi Alijanianzadeh, Thanigaimalai Pillaiyar, Pablo Garcia-Molina, Francisco Garcia-Canovas, Jose Munoz-Munoz, Ali Akbar Saboury
Summary: Hyperpigmentation is a common and distressing dermatologic condition. Inhibition of tyrosinase is considered a logical approach to prevent the accumulation of melanin in the skin. Non-hydroquinone lightening agents and nano-based strategies have been developed as alternatives for treating hyperpigmentation.
BIOCHEMICAL PHARMACOLOGY
(2023)
Editorial Material
Neurosciences
Cheryl D. Conrad
Summary: This study provides a descriptive analysis of biological, psychological, and socioemotional markers of stress in individuals who self-identify as being either 'very stressed out' or 'zen'.
NEUROBIOLOGY OF STRESS
(2022)
Editorial Material
Chemistry, Multidisciplinary
Benjamin A. Suslick, Robert B. Grubbs, Robert M. Waymouth, Jeffrey S. Moore
Summary: The authors of this tribute article are alumni of the Grubbs group, spanning multiple generations, who possess unique perspectives on Bob throughout his life and career. Despite working with Bob in different roles and at different times, they all fondly remember their time with him and wish to commemorate the profound impact he had on their lives and careers.
Editorial Material
Biochemistry & Molecular Biology
Jens Puschhof, Eran Elinav
Summary: Human microbiome research is transitioning from association-based studies to understanding the effects of active strains on the human body. Despite challenges, progress has been made in utilizing data-driven microbiome diagnostics and interventions, potentially leading to breakthroughs in precision medicine in the next decade.
Review
Biotechnology & Applied Microbiology
Shyambabu Chaurasiya, Yuman Fong
Summary: Virotherapy, using live viruses as therapeutics, is a relatively novel field in cancer treatment. Breast cancer, the most common cancer in women worldwide, lacks effective treatments for metastatic cases. Virotherapy shows promise as a potential treatment option with fewer side effects for breast cancer patients.
CANCER GENE THERAPY
(2021)
Article
Fisheries
Sasa Raicevich, Bryony A. Caswel, Valerio Bartolino, Massimiliano Cardinale, Tyler D. Eddy, Ioannis Giovos, Ann-Katrien Lescrauwaet, Ruth H. Thurstan, Georg H. Engelhard, Emily S. Klein
Summary: Sidney J. Holt was not only a founding father of quantitative fisheries science and a key figure in saving great whales, but also a champion of reductionism and a systemic thinker who inspired critical thinking in marine conservation and management. His work across themes such as maximum sustainable yield, marine mammal conservation, ecosystem-based marine management, and historical perspectives emphasized evidence-based solutions and the precautionary principle. There are valuable lessons to be learned from his collaborative and evidence-driven approach for current and future generations of scientists.
ICES JOURNAL OF MARINE SCIENCE
(2021)
Review
Oncology
Ava Saidian, Isabella Dolendo, Andrew Sharabi, Tyler F. Stewart, Brent Rose, Rana R. McKay, Aditya Bagrodia, Amirali Salmasi
Summary: Recent studies have shown that combining immunotherapy with radiotherapy may have a synergistic effect in the treatment of bladder and prostate cancer. This article reviews the available data on combination immunotherapy and radiotherapy and discusses the potential benefits of this approach. Although there is evidence of the immunomodulating effects of radiation therapy, further clinical trials are needed to fully integrate immunotherapy into standard treatments for genitourinary cancers.
Review
Biochemistry & Molecular Biology
Mohsen Akbarian
Summary: Proteins and peptides are widely used in various industries such as pharmaceutical, health, food, textile, and biofuel, attracting attention especially in the pharmaceutical field. The demand for these drugs is increasing annually due to their high performance and low side effects.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Analytical
Balint Reho, Lukas Lau, Gabor Mocsar, Gabriele Mueller, Lina Fadel, Peter Brazda, Laszlo Nagy, Katalin Toth, Gyorgy Vamosi
ANALYTICAL CHEMISTRY
(2020)
Article
Biochemistry & Molecular Biology
Kathrin Lehmann, Suren Felekyan, Ralf Kuehnemuth, Mykola Dimura, Katalin Toth, Claus A. M. Seidel, Joerg Langowski
NUCLEIC ACIDS RESEARCH
(2020)
Article
Biochemistry & Molecular Biology
Piersandro Pallavicini, Lorenzo De Vita, Francesca Merlin, Chiara Milanese, Mykola Borzenkov, Angelo Taglietti, Giuseppe Chirico
Article
Materials Science, Multidisciplinary
Amirbahador Zeynali, Mario Marini, Giuseppe Chirico, Margaux Bouzin, Mykola Borzenkov, Laura Sironi, Laura D'Alfonso, Piersandro Pallavicini, Valeria Cassina, Francesco Mantegazza, Francesca Granucci, Laura Marongiu, Dario Polli, Alejandro De la Cadena, Maddalena Collini
ADVANCED OPTICAL MATERIALS
(2020)
Article
Chemistry, Multidisciplinary
Mykola Borzenkov, Giuseppe Chirico, Piersandro Pallavicini, Paola Sperandeo, Alessandra Polissi, Giacomo Dacarro, Lavinia Doveri, Maddalena Collini, Laura Sironi, Margaux Bouzin, Laura D'Alfonso
Article
Materials Science, Multidisciplinary
Mario Marini, Margaux Bouzin, Laura Sironi, Laura D'Alfonso, Roberto Colombo, Daniela Di Martino, Giuseppe Gorini, Maddalena Collini, Giuseppe Chirico
Summary: Thermal conductivity measurements are crucial in the applied physical sciences, requiring new non-invasive methods for high-resolution spatial mapping. A novel method for quantitative thermal conductivity mapping at around 10 μm resolution was proposed and experimentally demonstrated in this work.
MATERIALS TODAY PHYSICS
(2021)
Review
Chemistry, Multidisciplinary
Piersandro Pallavicini, Giuseppe Chirico, Angelo Taglietti
Summary: The photothermal properties of nanoparticles have been extensively studied, primarily in relation to tumor therapy and antibacterial coatings. There has been significant progress in various technological and biomedical applications, ranging from solar energy conversion to anticounterfeit printing.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Review
Chemistry, Analytical
Margaux Bouzin, Amirbahador Zeynali, Mario Marini, Laura Sironi, Riccardo Scodellaro, Laura D'Alfonso, Maddalena Collini, Giuseppe Chirico
Summary: Laser 3D printing and ablation techniques have enabled the creation of stimulus-responsive optical polymers, such as hydrogels, for a variety of applications including imaging, thermal stimulation, and sensing. Embedding active nanomaterials in microstructures can provide biocompatible structures with physically or chemically activatable features, contributing to advancements in nanomedicine and personalized medicine micro-devices.
Article
Materials Science, Multidisciplinary
Claudio Conci, Emanuela Jacchetti, Laura Sironi, Lorenzo Gentili, Giulio Cerullo, Roberto Osellame, Giuseppe Chirico, Manuela Teresa Raimondi
Summary: The current methods for assessing biomaterial biocompatibility are outdated and unethical, and there is a need for a real-time research method. This study develops and validates the Microatlas window, providing a chicken embryo experimental model for biomaterial biocompatibility assessment and microscope field repositioning.
ADVANCED OPTICAL MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Stefania Blasa, Mykola Borzenkov, Valentina Pastori, Lavinia Doveri, Piersandro Pallavicini, Giuseppe Chirico, Marzia Lecchi, Maddalena Collini
Summary: Targeted thermal stimulation induces morphological and functional differentiation of neurons, suggesting potential future application for modifying neuronal behavior in vivo.
Article
Biochemistry & Molecular Biology
Balint Reho, Lina Fadel, Peter Brazda, Anass Benziane, Eva Hegedus, Pialy Sen, Theodorus W. J. Gadella, Katalin Toth, Laszlo Nagy, Gyorgy Vamosi
Summary: We found that nuclear receptors (NRs) compete for DNA binding in a ligand-dependent manner, with retinoic acid receptor (RAR) dominating over vitamin D receptor (VDR) in the absence of agonist or with both agonists present. Both RAR and VDR reduce the DNA-bound fraction of each other in the absence of ligand, and the competing NR's agonist decreases the DNA-bound fraction of the other NR. These findings provide insights into the possible amelioration of side effects in NR-ligand-based therapies and complement the model of NR action involving competition for retinoid X receptor (RXR) and DNA sites.
JOURNAL OF BIOLOGICAL CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Sonia Colombo, Maddalena Collini, Laura D'Alfonso, Giuseppe Chirico, Enzo Martegani
Summary: This study reveals that the Ras/cAMP/PKA pathway plays a crucial role in regulating the response to nutrients' availability and stress in budding yeast. The activity of this pathway leads to noisy oscillations of cAMP levels, which in turn affects the nuclear accumulation of the transcription factor Msn2. Using a sensor, the researchers were able to detect the changes in cAMP concentrations in single yeast cells and observed oscillations under conditions of nutritional stress caused by limiting glucose availability.
Article
Biochemical Research Methods
Mario Marini, Amirbahador Zeynali, Maddalena Collini, Margaux Bouzin, Laura Sironi, Laura D'Alfonso, Francesco Mantegazza, Valeria Cassina, Giuseppe Chirico
Summary: The study discusses the impact of bendable structures under continuous flow, fabricates flexible microstructures using two-photon laser polymerization, and characterizes their bending dynamics and elastic properties. The results show a correlation between the elastic constant of the microstructures and the deflection-flow dependence, suggesting potential value for the development of energy conversion platforms.
Article
Physics, Multidisciplinary
R. Scodellaro, M. Bouzin, F. Mingozzi, F. Granucci, L. D'Alfonso, M. Collini, G. Chirico, L. Sironi
Summary: This study demonstrates that collagen organization can serve as a marker for early tumor diagnosis. By utilizing a machine learning algorithm, accurate discrimination between tumor areas and surrounding tissue can be achieved.
NUOVO CIMENTO C-COLLOQUIA AND COMMUNICATIONS IN PHYSICS
(2021)
Proceedings Paper
Materials Science, Biomaterials
Manuela T. Raimondi, Bianca Barzaghini, Alberto Bocconi, Claudio Conci, Chiara Martinelli, Alessandra Nardini, Carolina Testa, Stephana Carelli, Giulio Cerullo, Giuseppe Chirico, Riccardo Gottardi, Roberto Osellame, Andrea Remuzzi, Matteo Lagana, Emanuela Jacchetti
Summary: The research team developed various bioengineered cell models to recapitulate different biological processes such as cartilage regeneration and bone metastasis formation. By using two-photon laser polymerization to fabricate micro scaffolds, they were able to control stem cell function and enhance their stemness and pluripotency. This opens up new possibilities for safer use of stem cells in therapy.
OPTICAL METHODS FOR INSPECTION, CHARACTERIZATION, AND IMAGING OF BIOMATERIALS V
(2021)
