Article
Chemistry, Analytical
Juliane Vigano, Vitor L. Sanches, Leonardo M. de Souza Mesquita, Mariana C. de Souza, Laise C. da Silva, Jaisa O. Chaves, Tania Forster-Carneiro, Mauricio A. Rostagno
Summary: This study discusses a new system for comprehensive analysis of phenolic compounds in natural products, based on bidimensional separation of pressurized liquid extraction and in-line solid-phase extraction coupled with HPLC-PDA.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Cezar A. Bizzi, Matheus F. Pedrotti, Diogo M. Betiolo, Mariele S. Nascimento, Edson Muller, Giancarlo Cravotto, Erico M. M. Flores
Summary: Efforts have been made to improve digestion efficiency by using a digestion system pressurized with O-2, which reduced the amount of acid without impacting efficiency. The system successfully digested various organic matrices with high efficiency, and accurately determined elements using ICP-OES. High accuracy was achieved with minimal reagent usage, in line with green chemistry recommendations.
ANALYTICAL METHODS
(2021)
Review
Chemistry, Applied
Samara Soares, Liz Mary B. Moraes, Fabio R. P. Rocha, Alex Virgilio
Summary: This article evaluates the analytical methods for quality control of milk and dairy products, proposing a diversity of choices from traditional methods to innovative proposals. The results demonstrate the predominance of microwave-assisted acid digestion for sample mineralization and plasma-based techniques for elemental determination.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Biochemical Research Methods
Lucas Schmidt, Kayla Peterson, Thieli Schaefer Nunes, Malgorzata Knap, Lauren Petrick, Julio Alberto Landero-Figueroa
Summary: VAMS is a simple and safe method for collecting and storing blood samples. This study presents a new method for determining trace elements in VAMS-collected blood samples using microwave-assisted digestion and ICP-QQQ. The method showed high precision, accuracy, and efficiency, contributing to the advancement of trace element analysis in biomedical research and clinical applications.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Applied
Elsa Vasco, M. Grata Dias, Luisa Oliveira
Summary: The first Total Diet Study was conducted in Portugal, detailing the study planning, sample collection, and preparation process. By using harmonised procedures, exposure assessment can be compared with other countries and exposure trends can be evaluated.
Review
Chemistry, Analytical
Huasheng Lai, Gongke Li, Zhuomin Zhang
Summary: This review discusses the challenges in safety analysis of aquatic products and the use of advanced materials in sample preparation to enhance extraction, enrichment, and separation for target analytes. It specifically focuses on the application of advanced materials such as carbon materials, metal organic frameworks, and molecularly/ions imprinted polymers in improving safety analysis results. Conclusions and future perspectives on the use of advanced materials in sample preparation and safety analysis of aquatic products are also provided.
JOURNAL OF SEPARATION SCIENCE
(2021)
Article
Engineering, Chemical
Matteo Volpi, Camillo Pirola, Gianpaolo Rota, Joaquim A. Nobrega, Diego Carnaroglio
Summary: The lithium-ion industry requires high amounts of high purity lithium, with spodumene and brine being the major sources. Spodumene has multiple forms, with α-spodumene being the natural occurrence and highly resistant to chemical attack. A microwave-assisted chemical analysis procedure was developed to determine lithium and other metals in α-spodumene, using a mixture of sulfuric and phosphoric acids and diluted hydrofluoric acid solution. The feasibility of using ammonium fluoride instead of hydrofluoric acid was also demonstrated.
MINERALS ENGINEERING
(2022)
Article
Chemistry, Applied
Allana S. dos Santos, Pietra Strauch, Maria Gracas A. Korn, Rodolfo M. M. Santana
Summary: Two sample preparation procedures were developed for the analysis of nutritional content in white cheeses. Both procedures showed accuracy and precision for the analysis of calcium, potassium, phosphorus, sodium, and zinc. The type of cheese influenced the variation in nutrient content, and there was a lack of uniformity in nutritional composition.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Review
Food Science & Technology
Athanasios Kourkopoulos, Dick T. H. M. Sijm, Misha F. Vrolijk
Summary: The EU lacks specific legislation for paper and cardboard food contact materials, and national legislation differs among member states. There is a wide variability of protocols and conditions used in scientific studies, making comparisons difficult. The procedures and conditions laid down in EU legislation for plastics and European Standards may serve as a good basis for future assessment of paper and cardboard food contact materials.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2022)
Article
Food Science & Technology
Sri Harminda Pahm Hartantyo, Renuka Selvaraj, Jiaying Ho, Jia Quan Oh, Jun Cheng Er, Angela Li, Kyaw Thu Aung
Summary: We conducted a survey on caterers with and without past hygiene violations to investigate their staffing, food safety practices, and correlations with microbial counts in food and the processing environment. The study found that past infringements did not have a negative impact on the current execution of food safety measures or the microbial quality of food. Instead of imposing stricter regulations on errant operators, alternative efforts to enhance food safety and their policy implications are discussed.
Review
Biochemistry & Molecular Biology
Van-An Duong, Hookeun Lee
Summary: Liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based proteomics is a powerful technique for analyzing cellular, tissue, and fluid proteomes. While LC-MS/MS and data analysis techniques have been well-developed, sample preparation remains a challenging and laborious process. In this review, various methods for sample preparation in proteomics, as well as devices and methods for integrating different steps of sample preparation and peptide fractionation, are outlined and discussed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Chemistry, Analytical
Jelmir Craveiro de Andrade, Diego Galvan, Luciane Effting, Leticia Tessaro, Adriano Aquino, Carlos Adam Conte-Junior
Summary: Brazil produces a large amount of fruits and vegetables annually, requiring significant pesticide use. Monitoring pesticide residues in these foods is a challenging task, but various adaptations to conventional techniques have been developed to address this issue. The study reveals that organophosphate and pyrethroid residues are frequently detected in Brazilian fruits and vegetables.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2023)
Article
Biochemical Research Methods
Maxwell C. McCabe, Lauren R. Schmitt, Ryan C. Hill, Monika Dzieciatkowska, Mark Maslanka, Willeke F. Daamen, Toin H. van Kuppevelt, Danique J. Hof, Kirk C. Hansen
Summary: The study reveals the challenge of identifying proteins in the extracellular matrix but demonstrates a significant improvement through optimized extraction methods. Different approaches to ECM extraction were explored in the research, providing insights for better evaluation of ECM proteins.
MOLECULAR & CELLULAR PROTEOMICS
(2021)
Article
Chemistry, Analytical
David J. Cocovi-Solberg, Stephan Schnidrig, Stephan Hann
Summary: Turbulent flow chromatography is an online solid phase extraction technique that requires specific hardware and expensive consumables, but a new study has demonstrated its potential with off-the-shelf components and niche bead injection method, achieving higher pressure and sample throughput. Real-time pressure feedback control has been used for unattended operation, showing similar performance to previous literature and demonstrating additional sample preparation capabilities.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2021)
Article
Environmental Sciences
Siebe Lievens, Thomas Slegers, Maarten A. Mees, Wim Thielemans, Giulia Poma, Adrian Covaci, Mik Van Der Borght
Summary: Plastics are widely produced and used globally, resulting in the presence of plastic particles in the environment and food. Plastic particles can also be found in energy-rich waste biomass from the food industry, supermarkets, and restaurants. These waste streams can be used for biogas production or as feed for insects, which convert it into valuable biomass. However, the presence of plastic particles in these applications poses a threat to the environment, as well as human and animal health. Therefore, there is a need to determine the (micro)plastic content to assess the potential danger. A closed-vessel microwave-assisted acid digestion method was developed to accurately determine the meso- and microplastic content in food matrices. The method was tested on different plastics mixed with a food matrix, resulting in high plastic recovery and minimal changes to the intrinsic characteristics of the plastics.
ENVIRONMENTAL POLLUTION
(2022)
Article
Chemistry, Analytical
Diogo L. R. Novo, Priscila T. Scaglioni, Rodrigo M. Pereira, Filipe S. Rondan, Gilberto S. Coelho Junior, Marcia F. Mesko
Summary: The study proposed a green, safe, accurate, precise, and sensitive method for animal feed quality control. By evaluating the synergic effect between microwave and ultraviolet radiations, phosphorus and sulfur content was efficiently determined, with results comparable to traditional and official methods.
CURRENT ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Diogo La Rosa Novo, Thibaut Van Acker, Joke Belza, Frank Vanhaecke, Marcia Foster Mesko
Summary: Laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) was used to determine the concentrations of bromine (Br) and iodine (I) in human hair strands of individuals under synthetic thyroid hormone treatment. Matrix-matched external calibration standards were prepared using spiked hair strands. The results obtained by LA-ICP-MS were in agreement with those determined by pneumatic nebulization-ICP-MS after digestion. Subjects under treatment with synthetic thyroid hormones showed higher iodine concentrations compared to healthy subjects.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2022)
Article
Chemistry, Analytical
Mariele S. Nascimento, Gabriel T. Druzian, Leticia S. F. Pereira, Marcia F. Mesko, Rochele S. Picoloto, Paola A. Mello, Erico M. M. Flores
Summary: A microwave-assisted extraction method was developed for determining Cl, Br, and I in medicinal plants. The method showed accurate and reliable results compared to a reference method using ICP-MS. Care should be taken to control the carbon content to avoid interference.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2022)
Article
Green & Sustainable Science & Technology
Daniel Santos, Karen Giacobe, Carolina M. Silva, Loisleini F. Saldanha, Ayrton F. Martins, Erico M. M. Flores, Cezar A. Bizzi
Summary: Lignocellulosic materials are a promising alternative source for producing liquid biofuel and fine chemicals with low environmental impact, but they can be contaminated with metals and nonmetals. This study successfully utilized ultrasound energy to remove impurities from sugarcane straw, increasing fermentable sugars' production and demonstrating high efficiency in demineralization. The scaling up experiments also showed the potential applicability of ultrasound-assisted procedure for large-scale demineralization.
Article
Green & Sustainable Science & Technology
Alessandra Schneider Henn, Angelica Chaiani Frohlich, Matheus Felipe Pedrotti, Vitoria Hagemann Cauduro, Marcos Leandro Silva Oliveira, Erico Marlon de Moraes Flores, Cezar Augusto Bizzi
Summary: The study utilized microwave-assisted solid sampling analysis coupled to flame furnace atomic absorption spectrometry for Cd and Pb determination in food-contact polymer samples, aiming to minimize reagents and laboratory waste. The method showed accurate results with minimal waste generation, making it suitable for Cd and Pb determination in food-contact polymers.
Article
Green & Sustainable Science & Technology
Vitoria Hagemann Cauduro, Alessandra Schneider Henn, Rochele Sogari Picoloto, Edson Irineu Muller, Marcia Foster Mesko, Erico Marlon Moraes Flores
Summary: This study developed two methods using diluted acids for the digestion of oral pharmaceutical drugs and determination of elemental impurities. The efficiency of these methods was evaluated, and the results showed that they are effective for commercial drugs.
Article
Chemistry, Analytical
Sandra M. Cruz, Gabriel T. Druzian, Rafael F. Santos, Marcia F. Mesko, Fabio A. Duarte, Erico M. M. Flores
Summary: In this study, high purity graphite was effectively digested using a single method, allowing for the determination of halogens using multiple techniques. The microwave-induced self-ignition (MISI) system combined with pressurized oxygen enabled rapid digestion of carbon-based materials and accurate determination of halogens. This method eliminates the need for additional ignition aids and utilizes a diluted absorbing solution with low blank values.
ANALYTICA CHIMICA ACTA
(2022)
Article
Neurosciences
Maria Rosula Poetini, Aparecida Santos Musachio Elize, Machado Araujo Stifani, Cardoso Bortolotto Vandreza, Barreto Meichtry Luana, C. Prime Aceres Silva Neici, Espinosa Janner Dieniffer, La Rosa Novo Diogo, Foster Mesko Marcia, Roehrs Rafael, Bruna Piaia Ramborger, Marina Prigol
Summary: This study aimed to evaluate the effects of hesperidin on motor and non-motor alterations in a Parkinson-like disease model in fruit flies. The results showed that hesperidin could alleviate motor and non-motor alterations and reduce iron levels in the flies' heads.
Article
Green & Sustainable Science & Technology
Simone Sehnem, Leonice Troiani, Ana Claudia Lara, Marcelo Guerreiro Crizel, Luciano Carvalho, Vinicius Picanco Rodrigues
Summary: The textile sector is recognized as one of the most polluting industries in society, and the educational sector plays a strategic role in transforming the value-added products in the textile production chain. This study aims to validate the theoretical assumptions of teaching sustainability and circular economy practices. The results show a lack of emphasis on teaching good sustainability practices in the analyzed Fashion Design courses in Brazil. Although sustainability and circular economy practices have been internalized, there is a need to further develop and prioritize practices associated with the core of the circular economy. These practices have the potential to generate innovative solutions for the sustainable fashion segment.
ENVIRONMENT DEVELOPMENT AND SUSTAINABILITY
(2023)
Article
Agriculture, Multidisciplinary
Priscila T. Scaglioni, Fernanda P. Balbinot, Filipe S. Rondan, Diogo L. R. Novo, Alisson A. Silva, Marcia F. . Mesko
Summary: A strategy using microwave-induced combustion (MIC) and ion chromatography coupled to mass spectrometry (IC-MS) was proposed for the determination of bromine and iodine bioaccessibility from edible seaweeds after in vitro digestion. The concentrations of bromine and iodine in edible seaweeds using the proposed methods were comparable to those obtained using conventional methods. Trueness was assessed by recovery experiments and the results showed good accuracy. MIC was proposed as a sample preparation method for bioaccessible and residual fractions.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Chemistry, Analytical
Marcia Foster Mesko, Rodrigo Mendes Pereira, Natalia Jorge Bielemann, Filipe Soares Rondan, Diogo La Rosa Novo
Summary: In this study, microwave-induced combustion (MIC) was combined with ion chromatography (IC) and ion-selective electrode potentiometry (ISE) for iodine determination in mineral dietary supplements. The method was successfully applied for iodine determination in supplements from four brands with different iodine dosages. Non-compliance regarding label information for some samples was reported.
BRAZILIAN JOURNAL OF ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Gabriel T. Druzian, Mariele S. Nascimento, Rochele S. Picoloto, Marcia F. Mesko, Erico M. M. Flores, Paola A. Mello
Summary: A method for determining sub-ppb levels of mercury in crude oil using cold vapor generation inductively coupled plasma mass spectrometry (CV-ICP-MS) was developed by optimizing the operational parameters for crude oil digestion and evaluating the accuracy of the method. The optimized conditions allowed for the complete digestion of up to 1.2 g of crude oil and achieved a very low limit of detection.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2022)
Article
Chemistry, Multidisciplinary
Wafa A. Bawazir, Maymoona A. Al-Mahmood, Rawan S. Almalki, Ghadi F. Alofi, Raghad S. Alharbi, Zoya Zaheer
Summary: This study investigates the interaction between sulfathiazole and three types of surfactants using UV-visible spectroscopy and conductivity measurements. The results show that the critical micelle concentration of cationic and anionic surfactants decreases with increasing sulfathiazole concentration, while the interaction with non-ionic surfactant is weak.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Musaad K. Aleid, Khalid N. Alharbi, Mona A. Aljufareen, Areej S. Aloliwi, Alhanouf K. Almutairi, Rahaf S. Alsaif, Nada K. Alshayeb, Mohammed S. Almoiqli
Summary: This study assessed the levels of trihalomethane compounds in the water network of Riyadh city and identified the factors influencing their formation. The concentrations of trihalomethane compounds were within the permissible limits, indicating the water's safety for human consumption. The presence of bromide ions, organic carbon, free chlorine, and pH values were found to affect trihalomethane formation.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Said Arhzaf, Jamal Houssaini, Mohammed Naciri Bennani, Marwa Alaqarbeh, Mohammed Bouachrine
Summary: The study shows that Mg-Al hydrotalcite catalysts intercalated with acetate and carbonate anions exhibit superior catalytic activity in the aldol condensation reaction between furfural and acetone. The optimal reaction conditions are at 90 degrees C for 2 hours, achieving conversion rates of over 98% with high selectivity towards F2A for the acetate catalyst.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Uyen-Chi Nguyen Le, Ngoc Xuan Dat Mai, Kieu-Minh Le, Hoang Anh Vu, Huynh-Nhu Thi Tran, Tan Le Hoang Doan
Summary: This study aimed to enhance the bioavailability of rosmarinic acid, a bioactive compound with high anticancer activity, by encapsulating it in tetrasulfide-based porous organosilica nanoparticles. The synthesized nanoparticles were small in size and had a high surface area and an average pore diameter. The nanoparticles showed effective accumulation in cancer cells without toxicity to normal cells. Treatment with rosmarinic acid-containing nanoparticles resulted in significant cell death in cancer cells. Overall, these findings suggest that the synthesized nanoparticles can enhance the pharmacological effects of rosmarinic acid.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Jiamin Qi, Hengxi Zhu, Tianyu Yang, Xingyuan Wang, Zixuan Wang, Xiaoli Lei, Bin Li, Wenmin Qian
Summary: This study synthesized a novel iron-biochar adsorbent using the iron content in red mud to remove heavy metals from wastewater. The adsorbent showed excellent removal efficiency and sustainability. This method addresses both industrial waste recovery and heavy metal adsorption issues.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Bo Yi, Li Zhang, Haiyang Zhou
Summary: Plasma protein binding plays a crucial role in the pharmacokinetics and pharmacodynamics of therapeutic bioactive materials. In this study, the interaction of nordentatin, a member of coumarins, with human alpha-1 acid glycoprotein (AGP) was investigated, and the anticancer potency of nordentatin against human colorectal cancer cells was evaluated. The results showed that nordentatin binds to AGP through a static quenching mechanism and exhibits inhibitory effects on the growth of HCT-116 cells by increasing intracellular ROS and [Ca2+] levels and triggering apoptosis-related gene overexpression. Therefore, nordentatin could be a promising plant-based therapy for colorectal cancer.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Qiming Pang, Cui Wang, Bangtao Li, Suli Zhang, Jiaoyang Li, Shuo Gu, Xueyu Shi
Summary: This study evaluated the effects of resveratrol loaded in copolymer nanoparticles on cerebral ischemia/reperfusion (I/R) injury in rats. The results showed that RES.CP.NPs could have neuroprotective effects through their antioxidant and anti-inflammatory activities, leading to improved neurological disability scores and decreased oxidative stress levels.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Maryam Rachmawati Sumitra, Lung-Ching Chen, Wei-Chen Tsai, Muhamad Ansar, Bashir Lawal, Ntlotlang Mokgautsi, Jih-Hwa Guh, Alexander T. H. Wu, Hsu-Shan Huang
Summary: Tetraheterocyclic compounds derived from natural sources and contemporary pharmaceuticals have shown promise as multitarget therapeutic agents. In this study, a series of synthesized compounds were evaluated for their potential in breast cancer treatment. Compounds 18 and 20 demonstrated significant antiproliferative activity against breast cancer cell lines and their mode of action was revealed through molecular docking simulations.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Mohammad Khosravani, Mohsen Dehghani Ghanatghestani, Farid Moeinpour, Hossein Parvaresh
Summary: The aim of removing Pb(II) from water is to minimize the potential harm posed by toxic metals to both human health and the environment. A covalent organic framework adsorbent called TFPOTDB-SO3H was developed with excellent properties such as high repeatability, selectivity, and easy solid-liquid separation. The adsorbent showed impressive capability of adsorbing Pb(II) and effective removal of it from a solution with various ions, suggesting its potential for effectively adsorbing and removing Pb(II) heavy metal ions from wastewater.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Ashraf H. Farha, Mohamed S. Shams, Hasna A. Alali, Zakia H. Alhashem, Shehab A. Mansour, Shrouq H. Aleithan, Ragab A. Elsad
Summary: The current study examines the dielectric and thermal properties of transformer oil incorporated with Mn0.5 Zn0.5 Fe2O4 nanoparticles. The results show that the addition of Mn-Zn ferrite NPs improves the dielectric constant, dissipation factor, AC breakdown voltage, and convective heat transfer of the nanofluid.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Limin Hou, Zongpei Jiang, Minqi Ye, Xueyan Sun, Kexin Liu, Yifan Zhu, Xiaoyu Wang, Liangzhu Chen, Ruiheng Gu, Binghu Fang
Summary: The excessive accumulation of antibiotic residue in animal-derived foods poses a threat to health. Therefore, it is necessary to establish a rapid, simple, effective, safe, and highly sensitive method for detecting lincomycin residues. By using a pre-column derivatization method on high-performance liquid chromatography equipped with ultraviolet, the UV absorption of lincomycin is improved, allowing for detection and quantification.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Kun Tang, Xin-Xin Wang, Jin-Jin Zhao, Ning Ren, Jian-Jun Zhang
Summary: This study reports the synthesis, crystal structures, and thermal degradation properties of three new rare earth coordination compounds. Compounds 1-3 exhibit binuclear structures which can form chain-like structures via hydrogen bonding. Compound 2 shows potential application value in the orange-red luminescence region.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Seoyoun Yang, Eunbi Yu, See-Hyoung Park, Sae Woong Oh, Kitae Kwon, Su Bin Han, Soo Hyun Kang, Jung Hyun Lee, Heejun Ha, Minkyung Song, Jae Youl Cho, Jongsung Lee
Summary: This study investigated the effects of blue light on the hypodermis and found that it has antiadipogenic properties by reducing lipid accumulation and downregulating the expression of adipogenic genes. Blue light also increased the phosphorylation of PPAR gamma and TRPV1, suggesting its anti-adipogenic effect through these signaling pathways.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Abdul Nasir, Abdul Waheed Khan, Hamid Rafiq Khattak, Abdus Samad, Sami Ullah, Haroon Khan, Muhammad Faheem, Qian Bai
Summary: This study evaluated the effects of isoxazolone derivatives on cisplatin-induced neuropathy in a rat model. The results showed that isoxazolone derivatives effectively reversed mechanical allodynia, similar to the known therapeutic agent pregabalin. Molecular docking analysis indicated that isoxazolone derivatives have strong binding affinity for relevant receptors and potential inhibitory activity against relevant signaling pathways. This study has innovative implications for the treatment of cisplatin-induced neuropathic pain.
ARABIAN JOURNAL OF CHEMISTRY
(2024)
Article
Chemistry, Multidisciplinary
Shahid Wahab, Haroon Muhammad Ali, Maham Khan, Tariq Khan, Chandran Krishnaraj, Soon-Il Yun
Summary: In this study, we synthesized chitosan nanoparticles, silver nanoparticles, and chitosan/silver nanocomposites using aqueous ginger extract as a green approach. These nanomaterials showed significant antibacterial properties and low toxicity. Furthermore, the nanomaterials conjugated with tobramycin demonstrated enhanced antibacterial efficacy and exhibited interactions with Pseudomonas aeruginosa.
ARABIAN JOURNAL OF CHEMISTRY
(2024)