4.8 Article

DMF-Promoted Redox-Neutral Ni-Catalyzed Intramolecular Hydroarylation of Alkene with Simple Arene

Journal

ACS CATALYSIS
Volume 8, Issue 5, Pages 3913-3917

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acscatal.8b00554

Keywords

nickel; redox-neutral; hydroarylation; alkene; arene

Funding

  1. National Natural Science Foundation of China [21672107]

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A redox-neutral Ni-catalyzed intramolecular hydroarylation of alkene with simple arene has been developed, in which DMF played a proton shuttle role in facilitating the intramolecular coupling, avoiding the use of additional reductants and oxidants. A series of oxindoles with a quaternary center were obtained in up to 99% yield.

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