Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP

Old dog, new tricks: novel cardiac targets and stress regulation by protein kinase G

(2016) Peter P. Rainer et al.   CARDIOVASCULAR RESEARCH

Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial InfarctionNovelty and Significance

(2016) Christiane Vettel et al.   CIRCULATION RESEARCH

Microdomain-Specific Modulation of L-Type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart FailureNovelty and Significance

(2016) Jose L. Sanchez-Alonso et al.   CIRCULATION RESEARCH

Molecular Physiology of Membrane Guanylyl Cyclase Receptors

(2016) Michaela Kuhn   PHYSIOLOGICAL REVIEWS

Microdomain Switch of cGMP-Regulated Phosphodiesterases Leads to ANP-Induced Augmentation of  -Adrenoceptor-Stimulated Contractility in Early Cardiac Hypertrophy

(2015) R. K. Perera et al.   CIRCULATION RESEARCH

Cardiac Hypertrophy Is Inhibited by a Local Pool of cAMP Regulated by Phosphodiesterase 2Novelty and Significance

(2015) Anna Zoccarato et al.   CIRCULATION RESEARCH

Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease

(2015) Dong I. Lee et al.   NATURE

In vivo model with targeted cAMP biosensor reveals changes in receptor–microdomain communication in cardiac disease

(2015) Julia U. Sprenger et al.   Nature Communications

Transgenic Mice for Real-Time Visualization of cGMP in Intact Adult Cardiomyocytes

(2014) Konrad R. Götz et al.   CIRCULATION RESEARCH

Bifurcation of Axons from Cranial Sensory Neurons Is Disabled in the Absence of Npr2-Induced cGMP Signaling

(2014) Gohar Ter-Avetisyan et al.   JOURNAL OF NEUROSCIENCE

Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure

(2014) John J.V. McMurray et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of Membrane Microdomains in Compartmentation of cAMP Signaling

(2014) Shailesh R. Agarwal et al.   PLoS One

Local Delivery of Molecules from a Nanopipette for Quantitative Receptor Mapping on Live Cells

(2013) Babak Babakinejad et al.   ANALYTICAL CHEMISTRY

Expression and localization of TRPC proteins in rat ventricular myocytes at various developmental stages

(2013) Yu Jiang et al.   CELL AND TISSUE RESEARCH

Stimulated Emission Depletion Live-Cell Super-Resolution Imaging Shows Proliferative Remodeling of T-Tubule Membrane Structures After Myocardial Infarction

(2012) Eva Wagner et al.   CIRCULATION RESEARCH

Designer natriuretic peptides: a vision for the future of heart failure therapeutics

(2011) Rosita Zakeri et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Stress-dependent dilated cardiomyopathy in mice with cardiomyocyte-restricted inactivation of cyclic GMP-dependent protein kinase I

(2011) Stefan Frantz et al.   EUROPEAN HEART JOURNAL

Guanylyl cyclase (GC)-A and GC-B activities in ventricles and cardiomyocytes from failed and non-failed human hearts: GC-A is inactive in the failed cardiomyocyte

(2011) Deborah M. Dickey et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Molecular mechanisms underlying cardiac antihypertrophic and antifibrotic effects of natriuretic peptides

(2011) Camilla Calvieri et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells

(2011) Sebastian Börner et al.   Nature Protocols

A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptide

(2011) M. Klaiber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of TRPC6 Channel Activity Contributes to the Antihypertrophic Effects of Natriuretic Peptides-Guanylyl Cyclase-A Signaling in the Heart

(2010) Hideyuki Kinoshita et al.   CIRCULATION RESEARCH

 2-Adrenergic Receptor Redistribution in Heart Failure Changes cAMP Compartmentation

(2010) V. O. Nikolaev et al.   SCIENCE

Dual Acylation of PDE2A Splice Variant 3

(2009) Corina Russwurm et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nanoscale live-cell imaging using hopping probe ion conductance microscopy

(2009) Pavel Novak et al.   NATURE METHODS

Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics

(2009) Emily J. Tsai et al.   PHARMACOLOGY & THERAPEUTICS

Simultaneous Live Cell Imaging Using Dual FRET Sensors with a Single Excitation Light

(2009) Yusuke Niino et al.   PLoS One

B-type natriuretic peptide (BNP) attenuates the L-type calcium current and regulates ventricular myocyte function

(2008) R. Sodi et al.   REGULATORY PEPTIDES