Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells

Dual signaling evoked by oxidized LDLs in vascular cells

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A functional genomics predictive network model identifies regulators of inflammatory bowel disease

(2017) Lauren A Peters et al.   NATURE GENETICS

Context-Dependent Role of Oxidized Lipids and Lipoproteins in Inflammation

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A Next Generation Multiscale View of Inborn Errors of Metabolism

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Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis

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Targeting MTHFD2 in acute myeloid leukemia

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A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

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Plasma Glycine and Risk of Acute Myocardial Infarction in Patients With Suspected Stable Angina Pectoris

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Differentiating connexin hemichannels and pannexin channels in cellular ATP release

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Quantitative flux analysis reveals folate-dependent NADPH production

(2014) Jing Fan et al.   NATURE

An atlas of genetic influences on human blood metabolites

(2014) So-Youn Shin et al.   NATURE GENETICS

Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease

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Inhibitors of ATP Release Inhibit Vesicular Nucleotide Transporter

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Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

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Identification of two genes potentially associated in iron-heme homeostasis in human carotid plaque using microarray analysis

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Identification of CAD candidate genes in GWAS loci and their expression in vascular cells

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Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells

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Mechanisms of ATP release and signalling in the blood vessel wall

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STRING v9.1: protein-protein interaction networks, with increased coverage and integration

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Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation

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ATP release and purinergic signaling: a common pathway for particle-mediated inflammasome activation

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Stitching together Multiple Data Dimensions Reveals Interacting Metabolomic and Transcriptomic Networks That Modulate Cell Regulation

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Mechanisms of ER Stress-Induced Apoptosis in Atherosclerosis

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Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

The Transcription Factor HOXC9 Regulates Endothelial Cell Quiescence and Vascular Morphogenesis in Zebrafish via Inhibition of Interleukin 8

(2011) Sandra J. Stoll et al.   CIRCULATION RESEARCH

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Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease

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Gene network inference and visualization tools for biologists: application to new human transcriptome datasets

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Systems Genetics Analysis of Gene-by-Environment Interactions in Human Cells

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Compartmentalization of Mammalian Folate-Mediated One-Carbon Metabolism

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Oxidized Phospholipids Regulate Expression of ATF4 and VEGF in Endothelial Cells via NRF2-Dependent Mechanism: Novel Point of Convergence Between Electrophilic and Unfolded Protein Stress Pathways

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Oxidized Low-Density Lipoprotein and Atherosclerosis

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Discovery of novel mechanosensitive genes in vivo using mouse carotid artery endothelium exposed to disturbed flow

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Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress

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The Rac1 Regulator ELMO1 Controls Vascular Morphogenesis in Zebrafish

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(2009) Cole Trapnell et al.   BIOINFORMATICS

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Chronic Endoplasmic Reticulum Stress Activates Unfolded Protein Response in Arterial Endothelium in Regions of Susceptibility to Atherosclerosis

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Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks

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ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells

(2009) Q. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nrf2 Regulates Antioxidant Gene Expression Evoked by Oxidized Phospholipids in Endothelial Cells and Murine Arteries In Vivo

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Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks

(2008) Jun Zhu et al.   NATURE GENETICS

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

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Mapping the Genetic Architecture of Gene Expression in Human Liver

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